Nephroscreen: A robust and versatile renal tubule-on-a-chip platform for nephrotoxicity assessment

Current Opinion in Toxicology - Tập 25 - Trang 42-48 - 2021
Jelle Vriend1, Marianne K. Vormann2, Henriëtte L. Lanz2, Jos Joore2, Sebastiaan J. Trietsch2, Frans G.M. Russel1, Björn Jacobsen3, Adrian Roth3, Shuyan Lu4, Joseph W. Polli5, Anita A. Naidoo6, Rosalinde Masereeuw7, Martijn J. Wilmer1, Laura Suter-Dick8,9
1Department of Pharmacology and Toxicology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, the Netherlands
2MIMETAS B.V, Leiden, the Netherlands
3Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland
4Pfizer Inc, San Diego, USA.
5Mechanistic Safety and Disposition, GlaxoSmithKline Upper Merion, King of Prussia, PA, USA
6Mechanistic Safety and Disposition, GlaxoSmithKline, Ware, UK
7Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht, The Netherlands
8School of Life Sciences, University of Applied Sciences Northwestern Switzerland, Muttenz, Switzerland
9Swiss Centre for Applied Human Toxicology (SCAHT), Basel, Switzerland

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