Nell-1 induced bone formation within the distracted intermaxillary suture

Abu-Serriah, 2003, The role of ultrasound in monitoring reconstruction of mandibular continuity defects using osteogenic protein-1 (rhOP-1), Int. J. Oral Maxillofac. Surg., 32, 619, 10.1054/ijom.2002.0421 Akiyama, 2002, The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6, Genes Dev., 16, 2813, 10.1101/gad.1017802 Andriano, 2000, Preliminary in vivo studies on the osteogenic potential of bone morphogenetic proteins delivered from an absorbable puttylike polymer matrix, J. Biomed. Mater. Res., 53, 36, 10.1002/(SICI)1097-4636(2000)53:1<36::AID-JBM5>3.0.CO;2-H Boden, 2002, Use of recombinant human bone morphogenetic protein-2 to achieve posterolateral lumbar spine fusion in humans: a prospective, randomized clinical pilot trial: 2002 Volvo Award in clinical studies, Spine, 27, 2662, 10.1097/00007632-200212010-00005 Bonewald, 2002, Transforming growth factor-beta, 903 Borah, 2000, Evaluation of changes in trabecular bone architecture and mechanical properties of minipig vertebrae by three-dimensional magnetic resonance microimaging and finite element modeling, J. Bone Miner. Res., 15, 1786, 10.1359/jbmr.2000.15.9.1786 Bornstein, 1995, Metaxin, a gene contiguous to both thrombospondin 3 and glucocerebrosidase, is required for embryonic development in the mouse: implications for Gaucher disease, Proc. Natl. Acad. Sci. U.S.A., 92, 4547, 10.1073/pnas.92.10.4547 Bouletreau, 2000, Gene expression of transforming growth factor-beta 3 and tissue inhibitor of metalloproteinase type 1 during membranous bone healing in rats, J. Craniofac. Surg., 11, 521, 10.1097/00001665-200011060-00003 Boyne, 1997, A feasibility study evaluating rhBMP-2/absorbable collagen sponge for maxillary sinus floor augmentation, Int. J. Periodontics Restor. Dent., 17, 11 Carette, 1992, The fate of medial edge epithelial cells during palatal fusion in vitro: an analysis by DiI labelling and confocal microscopy, Development, 114, 379, 10.1242/dev.114.2.379 Chen, 1993, Bone sialoprotein in developing porcine dental tissues: cellular expression and comparison of tissue localization with osteopontin and osteonectin, Arch. Oral Biol., 38, 241, 10.1016/0003-9969(93)90034-J Chen, 1991, Localization of bone sialoprotein (BSP) expression to sites of mineralized tissue formation in fetal rat tissues by in situ hybridization, Matrix, 11, 133, 10.1016/S0934-8832(11)80217-9 Cowan, 2004, Adipose-derived adult stromal cells heal critical-sized mouse calvarial defects, Nat. Biotechnol., 22, 560, 10.1038/nbt958 Cowan, 2004, Evolving concepts in bone tissue engineering, Curr. Top. Dev. Biol. Dhem, 2001, Chondroid tissue, Bull. Acad. Natl. Med., 185, 81 Dunn, 2005, BMP gene delivery for alveolar bone engineering at dental implant defects, Mol. Ther., 11, 294, 10.1016/j.ymthe.2004.10.005 Erbe, 1996, Long-term results of segmental repositioning of the maxilla in cleft palate patients without previously grafted alveolo-palatal clefts, J. Craniomaxillofac. Surg., 24, 109, 10.1016/S1010-5182(96)80022-9 Ferguson, 1988, Palate development, Development, 103, 41, 10.1242/dev.103.Supplement.41 Fitchett, 1989, Medial edge epithelium transforms to mesenchyme after embryonic palatal shelves fuse, Dev. Biol., 131, 455, 10.1016/S0012-1606(89)80017-X Geesink, 1999, Osteogenic activity of OP-1 bone morphogenetic protein (BMP-7) in a human fibular defect, J. Bone Joint Surg. Br., 81, 710, 10.1302/0301-620X.81B4.9311 Gerstenfeld, 1996, Expression of bone-specific genes by hypertrophic chondrocytes: implication of the complex functions of the hypertrophic chondrocyte during endochondral bone development, J. Cell Biochem., 62, 1, 10.1002/(SICI)1097-4644(199607)62:1<1::AID-JCB1>3.0.CO;2-X Gong, 2001, Effects of recombinant human basic fibroblast growth factor on cell proliferation during mandibular fracture healing in rabbits, Chin. J. Traumatol., 4, 110 Gosain, 2000, Osteogenesis in cranial defects: reassessment of the concept of critical size and the expression of TGF-beta isoforms, Plast. Reconstr. Surg., 106, 360, 10.1097/00006534-200008000-00018 Graham, 1994, The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest, Nature, 372, 684, 10.1038/372684a0 Gysin, 2002, Ex vivo gene therapy with stromal cells transduced with a retroviral vector containing the BMP4 gene completely heals critical size calvarial defect in rats, Gene Ther., 9, 991, 10.1038/sj.gt.3301772 Hanson, 2004, Alternative approach to assessment of bone quality using micro-computed tomography, Bone, 35, 326, 10.1016/j.bone.2004.02.019 Hinton, 1988, Response of the intermaxillary suture cartilage to alterations in masticatory function, Anat. Rec., 220, 376, 10.1002/ar.1092200406 Hogan, 1996, Bone morphogenetic proteins: multifunctional regulators of vertebrate development, Genes Dev., 10, 1580, 10.1101/gad.10.13.1580 Howell, 1997, A feasibility study evaluating rhBMP-2/absorbable collagen sponge device for local alveolar ridge preservation or augmentation, Int. J. Periodontics Restorative Dent., 17, 124 Hunziker, 1987, Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth, J. Bone Joint Surg. Am., 69, 162, 10.2106/00004623-198769020-00002 Ito, 2003, Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects, Development, 130, 5269, 10.1242/dev.00708 Joyce, 1991, Role of growth factors in fracture healing, Prog. Clin. Biol. Res., 365, 391 Kang, 2004, Characterization of the distinct orthotopic bone-forming activity of 14 BMPs using recombinant adenovirus-mediated gene delivery, Gene Ther., 11, 1312, 10.1038/sj.gt.3302298 Karadag, 2004, Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion, J. Natl. Cancer Inst., 96, 956, 10.1093/jnci/djh169 Krapels, 2004, Maternal nutritional status and the risk for orofacial cleft offspring in humans, J. Nutr., 134, 3106, 10.1093/jn/134.11.3106 Kuroda, 1999, Biochemical characterization and expression analysis of neural thrombospondin-1-like proteins NELL1 and NELL2, Biochem. Biophys. Res. Commun., 265, 79, 10.1006/bbrc.1999.1638 Kuroda, 1999, Involvement of epidermal growth factor-like domain of NELL proteins in the novel protein–protein interaction with protein kinase C, Biochem. Biophys. Res. Commun., 265, 752, 10.1006/bbrc.1999.1753 Lu, 2000, Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice, Arch. Oral. Biol., 45, 133, 10.1016/S0003-9969(99)00118-1 Macias, 1997, Role of BMP-2 and OP-1 (BMP-7) in programmed cell death and skeletogenesis during chick limb development, Development, 124, 1109, 10.1242/dev.124.6.1109 Matsumoto, 2001, Effect of aging on bone formation induced by recombinant human bone morphogenetic protein-2 combined with fibrous collagen membranes at subperiosteal sites, J. Periodontal. Res., 36, 175, 10.1034/j.1600-0765.2001.360306.x Mizoguchi, 1992, A comparison of the immunohistochemical localization of type I and type II collagens in craniofacial cartilages of the rat, Acta Anat. (Basel), 144, 59, 10.1159/000147286 Pacifici, 1990, Hypertrophic chondrocytes. The terminal stage of differentiation in the chondrogenic cell lineage?, Ann. N. Y. Acad. Sci., 599, 45, 10.1111/j.1749-6632.1990.tb42363.x Park, 1998, Controlled release of platelet-derived growth factor from porous poly(l-lactide) membranes for guided tissue regeneration, J. Control Release, 51, 201, 10.1016/S0168-3659(97)00169-7 Ramlee, 2001, Dimensions of stabident intraosseous perforators and needles, J. Endod., 27, 581, 10.1097/00004770-200109000-00007 Sculerati, 1998, Airway management in children with major craniofacial anomalies, Laryngoscope, 108, 1806, 10.1097/00005537-199812000-00008 Shea, 2003, BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis, J. Cell Biochem., 90, 1112, 10.1002/jcb.10734 Takahashi, 1996, Effects of expansive force on the differentiation of midpalatal suture cartilage in rats, Bone, 18, 341, 10.1016/8756-3282(96)00012-9 Ting, 1999, Human NELL-1 expressed in unilateral coronal synostosis, J. Bone Miner. Res., 14, 80, 10.1359/jbmr.1999.14.1.80 Urist, 1965, Bone: formation by autoinduction, Science, 150, 893, 10.1126/science.150.3698.893 Urist, 1971, Bone morphogenetic protein, J. Dent. Res., 50, 1392, 10.1177/00220345710500060601 van den Bergh, 2000, Recombinant human bone morphogenetic protein-7 in maxillary sinus floor elevation surgery in 3 patients compared to autogenous bone grafts. A clinical pilot study, J. Clin. Periodontol., 27, 627, 10.1034/j.1600-051x.2000.027009627.x Vehof, 2002, Bone formation in transforming growth factor beta-1-coated porous poly(propylene fumarate) scaffolds, J. Biomed. Mater. Res., 60, 241, 10.1002/jbm.10073 Vehof, 2001, Ectopic bone formation in titanium mesh loaded with bone morphogenetic protein and coated with calcium phosphate, Plast. Reconstr. Surg., 108, 434, 10.1097/00006534-200108000-00024 Walker, 2002, Bone morphogenetic proteins and spinal fusion, Neurosurg. Focus, 13, 10.3171/foc.2002.13.6.4 Watanabe, 1996, An immunohistochemical study of an anomaly of the fetal rat: adenohypophysis developing without contact with the brain, Arch. Histol. Cytol., 59, 381, 10.1679/aohc.59.381 Winn, 2000, Gene therapy approaches for modulating bone regeneration, Adv. Drug Deliv. Rev., 42, 121, 10.1016/S0169-409X(00)00057-0 Zhang, 2003, Overexpression of Nell-1, a craniosynostosis-associated gene, induces apoptosis in osteoblasts during craniofacial development, J. Bone Miner. Res., 18, 2126, 10.1359/jbmr.2003.18.12.2126 Zhang, 2002, Craniosynostosis in transgenic mice overexpressing Nell-1, J. Clin. Invest., 110, 861, 10.1172/JCI15375