Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism

Microbes and Infection - Tập 11 - Trang 811-819 - 2009
Tom Were1,2, Gregory C. Davenport3, Emmanuel O. Yamo1, James B. Hittner4, Gordon A. Awandare1,5, Michael F. Otieno6, Collins Ouma1, Alloys S.S. Orago7, John M. Vulule8, John M. Ong'echa1,3, Douglas J. Perkins1,3
1University of New Mexico/Kenya Medical Research Institute, Laboratories of Parasitic and Viral Diseases, Centre for Global Health Research, Kisumu, Kenya
2Department of Pathology, School of Health Sciences, Kenyatta University, Nairobi, Kenya
3Global and Geographic Medicine Program, Division of Infectious Diseases, University of New Mexico School of Medicine, NM, USA
4Department of Psychology, College of Charleston, Charleston, SC, USA
5Division of Malaria Vaccine Development, Walter Reed Army Institute of Research, Silver Spring, MD, USA
6Department of Pre-Clinical Sciences, School of Health Sciences, Kenyatta University, Nairobi, Kenya
7National AIDS Control Council, Nairobi, Kenya
8Centre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya

Tài liệu tham khảo

Abdalla, 2004 Scragg, 1999, Early cytokine induction by Plasmodium falciparum is not a classical endotoxin-like process, Eur J Immunol, 29, 2636, 10.1002/(SICI)1521-4141(199908)29:08<2636::AID-IMMU2636>3.0.CO;2-Y Kremsner, 1995, Prediction of accelerated cure in Plasmodium falciparum malaria by the elevated capacity of tumor necrosis factor production, Am J Trop Med Hyg, 53, 532, 10.4269/ajtmh.1995.53.532 Luty, 2000, Low interleukin-12 activity in severe Plasmodium falciparum malaria, Infect Immun, 68, 3909, 10.1128/IAI.68.7.3909-3915.2000 Perkins, 2000, Reduced interleukin-12 and transforming growth factor-beta1 in severe childhood malaria: relationship of cytokine balance with disease severity, J Infect Dis, 182, 988, 10.1086/315762 Ho, 1998, Endogenous interleukin-10 modulates proinflammatory response in Plasmodium falciparum malaria, J Infect Dis, 178, 520, 10.1086/515640 Othoro, 1999, A low interleukin-10 tumor necrosis factor-alpha ratio is associated with malaria anemia in children residing in a holoendemic malaria region in western Kenya, J Infect Dis, 179, 279, 10.1086/314548 Casals-Pascual, 2006, Suppression of erythropoiesis in malarial anemia is associated with hemozoin in vitro and in vivo, Blood, 108, 2569, 10.1182/blood-2006-05-018697 Lyke, 2003, Association of intraleukocytic Plasmodium falciparum malaria pigment with disease severity, clinical manifestations, and prognosis in severe malaria, Am J Trop Med Hyg, 69, 253, 10.4269/ajtmh.2003.69.253 Awandare, 2006, Decreased circulating macrophage migration inhibitory factor (MIF) protein and blood mononuclear cell MIF transcripts in children with Plasmodium falciparum malaria, Clin Immunol, 119, 219, 10.1016/j.clim.2005.12.003 Awandare, 2007, Role of monocyte-acquired hemozoin in suppression of macrophage migration inhibitory factor in children with severe malarial anemia, Infect Immun, 75, 201, 10.1128/IAI.01327-06 Ochiel, 2005, Differential regulation of beta-chemokines in children with Plasmodium falciparum malaria, Infect Immun, 73, 4190, 10.1128/IAI.73.7.4190-4197.2005 Were, 2006, Suppression of RANTES in children with Plasmodium falciparum malaria, Haematologica, 91, 1396 Li, 2001, Th1 cytokines stimulate RANTES chemokine secretion by human astroglial cells depending on de novo transcription, Neurochem Res, 26, 125, 10.1023/A:1011042711631 Marfaing-Koka, 1995, Regulation of the production of the RANTES chemokine by endothelial cells. Synergistic induction by IFN-gamma plus TNF-alpha and inhibition by IL-4 and IL-13, J Immunol, 154, 1870, 10.4049/jimmunol.154.4.1870 Hu, 1999, Inhibition of microglial cell RANTES production by IL-10 and TGF-beta, J Leukoc Biol, 65, 815, 10.1002/jlb.65.6.815 Marfaing-Koka, 1996, Contrasting effects of IL-4, IL-10 and corticosteroids on RANTES production by human monocytes, Int Immunol, 8, 1587, 10.1093/intimm/8.10.1587 Ambe, 2001, Associated morbidities in children with sickle-cell anaemia presenting with severe anaemia in a malarious area, Trop Doct, 31, 26, 10.1177/004947550103100109 Ong'echa, 2006, Parasitemia, anemia, and malarial anemia in infants and young children in a rural holoendemic Plasmodium falciparum transmission area, Am J Trop Med Hyg, 74, 376, 10.4269/ajtmh.2006.74.376 Keller, 2004, Reduced peripheral PGE2 biosynthesis in Plasmodium falciparum malaria occurs through hemozoin-induced suppression of blood mononuclear cell cyclooxygenase-2 gene expression via an interleukin-10-independent mechanism, Mol Med, 10, 45, 10.2119/2004-00035.Perkins John, 2006, Low levels of RANTES are associated with mortality in children with cerebral malaria, J Infect Dis, 194, 837, 10.1086/506623 Couper, 2008, IL-10 from CD4CD25Foxp3CD127 adaptive regulatory T cells modulates parasite clearance and pathology during malaria infection, PLoS Pathog, 4, e1000004, 10.1371/journal.ppat.1000004 D'Ombrain, 2007, Gammadelta-T cells expressing NK receptors predominate over NK cells and conventional T cells in the innate IFN-gamma response to Plasmodium falciparum malaria, Eur J Immunol, 37, 1863, 10.1002/eji.200636889 Good, 2005, Development and regulation of cell-mediated immune responses to the blood stages of malaria: implications for vaccine research, Annu Rev Immunol, 23, 69, 10.1146/annurev.immunol.23.021704.115638 Newman, 2006, Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria, PLoS Pathog, 2, e118, 10.1371/journal.ppat.0020118 Nie, 2007, CD4+ CD25+ regulatory T cells suppress CD4+ T-cell function and inhibit the development of Plasmodium berghei-specific TH1 responses involved in cerebral malaria pathogenesis, Infect Immun, 75, 2275, 10.1128/IAI.01783-06 Schofield, 2005, Immunological processes in malaria pathogenesis, Nat Rev Immunol, 5, 722, 10.1038/nri1686 Keller, 2006, Acquisition of hemozoin by monocytes down-regulates interleukin-12 p40 (IL-12p40) transcripts and circulating IL-12p70 through an IL-10-dependent mechanism: in vivo and in vitro findings in severe malarial anemia, Infect Immun, 74, 5249, 10.1128/IAI.00843-06 Perkins, 2003, In vivo acquisition of hemozoin by placental blood mononuclear cells suppresses PGE2, TNF-alpha, and IL-10, Biochem Biophys Res Commun, 311, 839, 10.1016/j.bbrc.2003.10.073 Moore, 2004, Hemozoin differentially regulates proinflammatory cytokine production in human immunodeficiency virus-seropositive and -seronegative women with placental malaria, Infect Immun, 72, 7022, 10.1128/IAI.72.12.7022-7029.2004 Chaiyaroj, 2004, Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria, Acta Trop, 89, 319, 10.1016/j.actatropica.2003.10.010 Tang, 2002, Antimicrobial peptides from human platelets, Infect Immun, 70, 6524, 10.1128/IAI.70.12.6524-6533.2002 Schofield, 1993, Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites, J Exp Med, 177, 145, 10.1084/jem.177.1.145