Bài tổng quan về cơ chế và điều trị cơn ho trong bệnh hen suyễn, ho do biến thể hen suyễn và viêm phế quản dị ứng không hen suyễn

Song WJ, Chang YS, Faruqi S, Kim JY, Kang MG, Kim S, Jo EJ, Kim MH, Plevkova J, Park HW, Cho SH, Morice AH (2015) The global epidemiology of chronic cough in adults: a systematic review and meta-analysis. Eur Respir J 45:1479–1481 Schappert SM, Burt CW (2006) Ambulatory care visits to physician offices, hospital outpatient departments, and emergency departments: United States, 2001–02. Vital Health Stat 159:1–66 Irwin RS, Baumann MH, Bolser DC, Boulet LP, Braman SS, Brightling CE, Brown KK, Canning BJ, Chang AB, Dicpinigaitis PV, Eccles R, Glomb WB, Goldstein LB, Graham LM, Hargreave FE, Kvale PA, Lewis SZ, McCool FD, McCrory DC, Prakash UBS, Pratter MR, Rosen MJ, Schulman E, Shannon JJ, Hammond CS, Tarlo SM (2006) Diagnosis and management of cough executive summary: ACCP evidence-based clinical practice guidelines. Chest 129:1S-23S Birring SS, Prudon B, Carr AJ, Singh SJ, Morgan MD, Pavord ID (2003) Development of a symptom specific health status measure for patients with chronic cough: Leicester Cough Questionnaire (LCQ). Thorax 58:339–343 French CL, Irwin RS, Curley FJ, Krikorian CJ (2024) Impact of chronic cough on quality of life. Arch Intern Med 158:1657–1661 Schappert SM, Rechtsteiner EA (2011) Ambulatory medical care utilization estimates for 2007. Vital Health Stat 169:1–38 Irwin RS, Curley FJ, French CL (1990) Chronic cough. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. Am Rev Respir Dis 141:640–647 Carney IK, Gibson PG, Murree-Allen K, Saltos N, Olson LG, Hensley MJ (1997) A systematic evaluation of mechanisms in chronic cough. Am J Respir Crit Care Med 156:211–216 Smyrnios NA, Irwin RS, Curley FJ (1995) Chronic cough with a history of excessive sputum production. The spectrum and frequency of causes, key components of the diagnostic evaluation, and outcome of specific therapy. Chest 108:991–997 Brightling CE, Ward R, Goh KL, Wardlaw AJ, Pavord ID (1999) Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med 160:406–410 Turcotte SE, Lougheed MD (2011) Cough in asthma. Curr Opin Pharmacol 11:231–237 Lai K, Chen R, Lin J, Huang K, Shen H, Kong L, Zhou X, Luo Z, Yang L, Wen F, Zhong N (2013) A prospective, multicenter survey on causes of chronic cough in China. Chest 143:613–620 Ayik SO, Başoğlu OK, Erdínç M, Bor S, Veral A, Bílgen C (2003) Eosinophilic bronchitis as a cause of chronic cough. Respir Med 97:695–701 Côté A, Russell RJ, Boulet LP, Gibson PG, Lai K, Irwin RS, Brightling CE, CHEST expert cough panel (2020) Managing chronic cough due to asthma and NAEB in adults and adolescents: CHEST guideline and expert panel report. Chest 158:68–96 Arinze JT, de Roos EW, Karimi L, Verhamme KM, Stricker BH, Brusselle GG (2020) Prevalence and incidence of, and risk factors for chronic cough in the adult population: the Rotterdam Study. ERJ Open Res 6:00300–02019 Çolak Y, Nordestgaard BG, Laursen LC, Afzal S, Lange P, Dahl M (2017) Risk factors for chronic cough among 14,669 individuals from the general population. Chest 152:563–573 Satia I, Mayhew AJ, Sohel N, Kurmi O, Killian KJ, O’Connell ME, O’Byrne PM, Raina P (2022) Language and geographical location influence the incidence of chronic cough in the Canadian Longitudinal Study on Aging. ERJ Open Res 8:00721–02021. https://doi.org/10.1183/23120541.00721 Louis R, Satia I, Ojanguren I, Schleich F, Bonini M, Tonia T, Rigau D, Ten Brinke A, Buhl R, Loukides S (2022) European Respiratory Society guidelines for the diagnosis of asthma in adults. Eur Respir J 6:2101585 Aaron SD, Vandemheen KL, FitzGerald JM, Ainslie M, Gupta S, Lemière C, Field SK, McIvor RA, Hernandez P, Mayers I, Mulpuru S, Alvarez GG, Pakhale S, Mallick R, Boulet LP, Canadian Respiratory Research Network (2017) Reevaluation of diagnosis in adults with physician-diagnosed asthma. JAMA 317:269–279 Aaron SD, Boulet LP, Reddel HK, Gershon AS (2018) Underdiagnosis and overdiagnosis of asthma. Am J Respir Crit Care Med 198:1012–1020 Corrao WM, Braman SS, Irwin RS (1979) Chronic cough as the sole presenting manifestation of bronchial asthma. N Engl J Med 300:633–637 Glauser FL (1972) Variant asthma. Ann Allergy 30:457–459 Yi F, Han L, Liu B, Zhang X, Xue Y, Luo W, Chen Q, Lai K (2020) Determinants of response to bronchodilator in patients with cough variant asthma-A randomized, single-blinded, placebo-controlled study. Pulm Pharmacol Ther 61:101903 Watanabe H, Shirai T, Akamatsu T, Asada K, Hirai K (2019) Forced oscillatory parameters in reversibility testing as predictors for chronic cough responsive to inhaled corticosteroid/long-acting β2 agonist. Ann Allergy Asthma Immunol 122:345-346.e1 Ohkura N, Fujimura M, Nakade Y, Okazaki A, Katayama N (2012) Heightened cough response to bronchoconstriction in cough variant asthma. Respirology 17:964–968 Matsumoto H, Niimi A, Takemura M, Ueda T, Yamaguchi M, Matsuoka H, Jinnai M, Chin K, Mishima M (2009) Features of cough variant asthma and classic asthma during methacholine-induced brochoconstriction: a cross-sectional study. Cough 5:3–9974 Gibson PG, Dolovich J, Denburg J, Ramsdale EH, Hargreave FE (1989) Chronic cough: eosinophilic bronchitis without asthma. Lancet 1:1346–1348 Belda J, Leigh R, Parameswaran K, O’Byrne PM, Sears MR, Hargreave FE (2000) Induced sputum cell counts in healthy adults. Am J Respir Crit Care Med 161:475–478 Kim MY, Jo EJ, Lee SE, Lee SY, Song WJ, Kim TW, Hur GY, Lee JH, Kim TB, Park HW, Chang YS, Park HS, Min KU, Cho SH (2014) Reference ranges for induced sputum eosinophil counts in Korean adult population. Asia Pac Allergy 4:149–155 Brightling CE (2006) Chronic cough due to nonasthmatic eosinophilic bronchitis: ACCP evidence-based clinical practice guidelines. Chest 129:116S-121S Song WJ, Kim HJ, Shim JS, Won HK, Kang SY, Sohn KH, Kim BK, Jo EJ, Kim MH, Kim SH, Park HW, Kim SS, Chang YS, Morice AH, Lee BJ, Cho SH (2017) Diagnostic accuracy of fractional exhaled nitric oxide measurement in predicting cough-variant asthma and eosinophilic bronchitis in adults with chronic cough: a systematic review and meta-analysis. J Allergy Clin Immunol 140:701–709 Rybka-Fraczek A, Dabrowska M, Grabczak EM, Bialek-Gosk K, Klimowicz K, Truba O, Nejman-Gryz P, Paplinska-Goryca M, Krenke R (2021) Blood eosinophils as a predictor of treatment response in adults with difficult-to-treat chronic cough. ERJ Open Res 7:00432–02021. https://doi.org/10.1183/23120541.00432 Canning BJ (2006) Anatomy and neurophysiology of the cough reflex: ACCP evidence-based clinical practice guidelines. Chest 129:33S-47S Canning B, Chou Y (2009) Cough sensors. I. Physiological and pharmacological properties of the afferent nerves regulating cough. In: Chung KF, Widdicombe J (eds) Pharmacology and therapeutics of cough. Springer, Berlin, pp 23–47 Mazzone SB, Undem BJ (2016) Vagal afferent innervation of the airways in health and disease. Physiol Rev 96:975–1024 Satia I, Nagashima A, Usmani OS (2020) Exploring the role of nerves in asthma; insights from the study of cough. Biochem Pharmacol 179:113901 Satia I, Wahab M, Kum E, Kim H, Lin P, Kaplan A, Hernandez P, Bourbeau J, Boulet LP, Field SK (2021) Chronic cough: investigations, management, current and future treatments. Can J Respir Crit Care Sleep Med 5:404–416 Hilton E, Satia I, Holt K, Woodcock AA, Belcher J, Smith JA (2020) The effect of pain conditioning on experimentally evoked cough: evidence of impaired endogenous inhibitory control mechanisms in refractory chronic cough. Eur Respir J 56:2001387 Gu Q, Lim ME, Gleich GJ, Lee LY (2009) Mechanisms of eosinophil major basic protein-induced hyperexcitability of vagal pulmonary chemosensitive neurons. Am J Physiol Lung Cell Mol Physiol 296:L453–L461 Lee LY, Widdicombe JG (2001) Modulation of airway sensitivity to inhaled irritants: role of inflammatory mediators. Environ Health Perspect 109(Suppl 4):585–589 Kwong K, Lee LY (1985) PGE(2) sensitizes cultured pulmonary vagal sensory neurons to chemical and electrical stimuli. J Appl Physiol 2002(93):1419–1428 Niimi A, Torrego A, Nicholson AG, Cosio BG, Oates TB, Chung KF (2005) Nature of airway inflammation and remodeling in chronic cough. J Allergy Clin Immunol 116:565–570 Bonvini SJ, Birrell MA, Dubuis E, Adcock JJ, Wortley MA, Flajolet P, Bradding P, Belvisi MG (2020) Novel airway smooth muscle-mast cell interactions and a role for the TRPV4-ATP axis in non-atopic asthma. Eur Respir J 56:1901458. https://doi.org/10.1183/13993003.01458-2019 Satia I, Watson R, Scime T, Dockry RJ, Sen S, Ford JW, Mitchell PD, Fowler SJ, Gauvreau GM, O’Byrne PM, Smith JA (2019) Allergen challenge increases capsaicin-evoked cough responses in patients with allergic asthma. J Allergy Clin Immunol 144:788-795.e1 Chu HW, Kraft M, Krause JE, Rex MD, Martin RJ (2000) Substance P and its receptor neurokinin 1 expression in asthmatic airways. J Allergy Clin Immunol 106:713–722 Cheung D, Van Der Veen H, Den Hartigh J, Dijkman J, Sterk P (1994) Effects of inhaled substance P on airway responsiveness to methacholine in asthmatic subjects in vivo. J Appl Physiol 77:1325–1332 Fajac I, Braunstein G, Lckovic M, Lacronique J, Frossard N (1995) Selective recruitment of eosinophils by substance P after repeated allergen exposure in allergic rhinitis. Allergy 50:970–975 Drake MG, Scott GD, Blum ED, Lebold KM, Nie Z, Lee JJ, Fryer AD, Costello RW, Jacoby DB (2018) Eosinophils increase airway sensory nerve density in mice and in human asthma. Sci Transl Med 10:eaar8477. https://doi.org/10.1126/scitranslmed.aar8477 Lieu TM, Myers AC, Meeker S, Undem BJ (2012) TRPV1 induction in airway vagal low-threshold mechanosensory neurons by allergen challenge and neurotrophic factors. Am J Physiol Lung Cell Mol Physiol 302:L941–L948 Chen CY, Bonham AC, Schelegle ES, Gershwin LJ, Plopper CG, Joad JP (2001) Extended allergen exposure in asthmatic monkeys induces neuroplasticity in nucleus tractus solitarius. J Allergy Clin Immunol 108:557–562 Marsden PA, Satia I, Ibrahim B, Woodcock A, Yates L, Donnelly I, Jolly L, Thomson NC, Fowler SJ, Smith JA (2016) Objective cough frequency, airway inflammation, and disease control in asthma. Chest 149:1460–1466 Morikawa T, Gallico L, Widdicombe J (1997) Actions of moguisteine on cough and pulmonary rapidly adapting receptor activity in the guinea pig. Pharmacol Res 35:113–118 Ohkura N, Fujimura M, Hara J, Ohsawa M, Kamei J, Nakao S (2009) Bronchoconstriction-triggered cough in conscious guinea pigs. Exp Lung Res 35:296–306 Satia I, Badri H, Woodhead M, O’Byrne PM, Fowler SJ, Smith JA (2017) The interaction between bronchoconstriction and cough in asthma. Thorax 72:1144–1146 Cusack R, Satia I, Howie K, Obminski C, Beaudin S, Schlatman A, Killian K, O'Byrne P, Gauvreau G (2020) Mannitol evoked cough responses; evidence of neuronal dysfunction in allergic asthmatics and females. In: Anonymous C21. Advances in adult and pediatric asthma phenotyping and endotyping. American Thoracic Society, p A4539 Satia I, Cusack R, Howie K, Obminski C, Beaudin S, Schlatman A, Killian K, O'Byrne P, Gauvreau G (2020) The effect of nebulized salbutamol on mannitol evoked cough responses in mild allergic asthmatics: a double-blind randomized placebo controlled 2-way cross-over study. In: Anonymous B31. Asthma clinical trials. American Thoracic Society, p A3006 Bonvini SJ, Birrell MA, Grace MS, Maher SA, Adcock JJ, Wortley MA, Dubuis E, Ching YM, Ford AP, Shala F, Miralpeix M, Tarrason G, Smith JA, Belvisi MG (2016) Transient receptor potential cation channel, subfamily V, member 4 and airway sensory afferent activation: role of adenosine triphosphate. J Allergy Clin Immunol 138:249-261.e12 Evans CM, Kim K, Tuvim MJ, Dickey BF (2009) Mucus hypersecretion in asthma: causes and effects. Curr Opin Pulm Med 15:4–11 Jinnai M, Niimi A, Ueda T, Matsuoka H, Takemura M, Yamaguchi M, Otsuka K, Oguma T, Takeda T, Ito I, Matsumoto H, Mishima M (2010) Induced sputum concentrations of mucin in patients with asthma and chronic cough. Chest 137:1122–1129 Alagha K, Bourdin A, Vernisse C, Garulli C, Tummino C, Charriot J, Vachier I, Suehs C, Chanez P, Gras D (2019) Goblet cell hyperplasia as a feature of neutrophilic asthma. Clin Exp Allergy 49:781–788 Lange P, Parner J, Vestbo J, Schnohr P, Jensen G (1998) A 15-year follow-up study of ventilatory function in adults with asthma. N Engl J Med 339:1194–1200 Dunican EM, Elicker BM, Gierada DS, Nagle SK, Schiebler ML, Newell JD, Raymond WW, Lachowicz-Scroggins ME, Di Maio S, Hoffman EA, Castro M, Fain SB, Jarjour NN, Israel E, Levy BD, Erzurum SC, Wenzel SE, Meyers DA, Bleecker ER, Phillips BR, Mauger DT, Gordon ED, Woodruff PG, Peters MC, Fahy JV, National Heart Lung and Blood Institute (NHLBI) Severe Asthma Research Program (SARP) (2018) Mucus plugs in patients with asthma linked to eosinophilia and airflow obstruction. J Clin Invest 128:997–1009 Irwin RS, French CL, Chang AB, Altman KW, CHEST expert cough panel* (2018) Classification of cough as a symptom in adults and management algorithms: CHEST Guideline and Expert Panel Report. Chest 153:196–209 Morice AH, McGarvey L, Pavord I, British Thoracic Society Cough Guideline Group (2006) Recommendations for the management of cough in adults. Thorax 61(Suppl 1):i1-24 Morice AH, Fontana GA, Sovijarvi AR, Pistolesi M, Chung KF, Widdicombe J, O’Connell F, Geppetti P, Gronke L, De Jongste J, Belvisi M, Dicpinigaitis P, Fischer A, McGarvey L, Fokkens WJ, Kastelik J, ERS Task Force (2004) The diagnosis and management of chronic cough. Eur Respir J 24:481–492 Johnstone KJ, Chang AB, Fong KM, Bowman RV, Yang IA (2013) Inhaled corticosteroids for subacute and chronic cough in adults. Cochrane Database Syst Rev 3:CD009305 Chaudhuri R, McMahon AD, Thomson LJ, MacLeod KJ, McSharry CP, Livingston E, McKay A, Thomson NC (2004) Effect of inhaled corticosteroids on symptom severity and sputum mediator levels in chronic persistent cough. J Allergy Clin Immunol 113:1063–1070 Ribeiro M, Pereira CA, Nery LE, Beppu OS, Silva CO (2007) High-dose inhaled beclomethasone treatment in patients with chronic cough: a randomized placebo-controlled study. Ann Allergy Asthma Immunol 99:61–68 Morice AH, Millqvist E, Bieksiene K, Birring SS, Dicpinigaitis P, Domingo Ribas C, Hilton Boon M, Kantar A, Lai K, McGarvey L, Rigau D, Satia I, Smith J, Song WJ, Tonia T, van den Berg JWK, van Manen MJG, Zacharasiewicz A (2020) ERS guidelines on the diagnosis and treatment of chronic cough in adults and children. Eur Respir J 55:1901136. https://doi.org/10.1183/13993003.01136-2019 Moeller M, Grimmbacher S, Munzel U (2008) Improvement of asthma therapy by a novel formoterol multidose dry powder inhaler. Arzneimittelforschung 58:168–173 Murali PM, Rajasekaran S, Krishnarajasekar OR, Perumal T, Nalini K, Lakshmisubramanian S, Deivanayagam CN (2006) Plant-based formulation for bronchial asthma: a controlled clinical trial to compare its efficacy with oral salbutamol and theophylline. Respiration 73:457–463 Irwin RS, French CT, Smyrnios NA, Curley FJ (1997) Interpretation of positive results of a methacholine inhalation challenge and 1 week of inhaled bronchodilator use in diagnosing and treating cough-variant asthma. Arch Intern Med 157:1981–1987 Tagaya E, Kondo M, Kirishi S, Kawagoe M, Kubota N, Tamaoki J (2015) Effects of regular treatment with combination of salmeterol/fluticasone propionate and salmeterol alone in cough variant asthma. J Asthma 52:512–518 Fukumitsu K, Kanemitsu Y, Asano T, Takeda N, Ichikawa H, Yap JMG, Fukuda S, Uemura T, Takakuwa O, Ohkubo H, Maeno K, Ito Y, Oguri T, Nakamura A, Takemura M, Niimi A (2018) Tiotropium attenuates refractory cough and capsaicin cough reflex sensitivity in patients with asthma. J Allergy Clin Immunol Pract 6:1613-1620.e2 Birrell MA, Bonvini SJ, Dubuis E, Maher SA, Wortley MA, Grace MS, Raemdonck K, Adcock JJ, Belvisi MG (2014) Tiotropium modulates transient receptor potential V1 (TRPV1) in airway sensory nerves: a beneficial off-target effect? J Allergy Clin Immunol 133:679–87.e9 Spector SL, Tan RA (2004) Effectiveness of montelukast in the treatment of cough variant asthma. Ann Allergy Asthma Immunol 93:232–236 Dicpinigaitis PV, Dobkin JB, Reichel J (2002) Antitussive effect of the leukotriene receptor antagonist zafirlukast in subjects with cough-variant asthma. J Asthma 39:291–297 Tamaoki J, Yokohori N, Tagaya E, Kirishi S, Miyamoto Y, Ochiai K, Kondo M, Nagai A (2010) Comparable effect of a leukotriene receptor antagonist and long-acting beta2-adrenergic agonist in cough variant asthma. Allergy Asthma Proc 31:78–84 Takemura M, Niimi A, Matsumoto H, Ueda T, Matsuoka H, Yamaguchi M, Jinnai M, Chin K, Mishima M (2012) Clinical, physiological and anti-inflammatory effect of montelukast in patients with cough variant asthma. Respiration 83:308–315 Miwa N, Nagano T, Ohnishi H, Nishiuma T, Takenaka K, Shirotani T, Nakajima T, Dokuni R, Kawa Y, Kobayashi K, Funada Y, Kotani Y, Nishimura Y (2018) An open-label, multi-institutional, randomized study to evaluate the additive effect of a leukotriene receptor antagonist on cough score in patients with cough-variant asthma being treated with inhaled corticosteroids. Kobe J Med Sci 64:E134–E139 Yousaf N, Monteiro W, Parker D, Matos S, Birring S, Pavord ID (2010) Long-term low-dose erythromycin in patients with unexplained chronic cough: a double-blind placebo controlled trial. Thorax 65:1107–1110 Hodgson D, Anderson J, Reynolds C, Oborne J, Meakin G, Bailey H, Shaw D, Mortimer K, Harrison T (2016) The effects of azithromycin in treatment-resistant cough: a randomized, double-blind placebo-controlled trial. Chest 149:1052–1060 Martin MJ, Lee H, Clayton C, Pointon K, Soomro I, Shaw DE, Harrison TW (2019) Idiopathic chronic productive cough and response to open-label macrolide therapy: an observational study. Respirology 24:558–565 Gibson PG, Yang IA, Upham JW, Reynolds PN, Hodge S, James AL, Jenkins C, Peters MJ, Marks GB, Baraket M, Powell H, Taylor SL, Leong LEX, Rogers GB, Simpson JL (2017) Effect of azithromycin on asthma exacerbations and quality of life in adults with persistent uncontrolled asthma (AMAZES): a randomised, double-blind, placebo-controlled trial. Lancet 390:659–668 Faruqi S, Sykes DL, Crooks MG, Brindle K, Thompson J, Morice AH (2020) Objective assessment of cough: an early marker of response to biological therapies in asthma? Lung 198:767–770 Zamora F, Cho R, Rao M, Gibson H, Dincer HE (2017) Endobronchial thermoplasty for asthma. J Vis Surg 3:127 Pretolani M, Bergqvist A, Thabut G, Dombret MC, Knapp D, Hamidi F, Alavoine L, Taillé C, Chanez P, Erjefält JS, Aubier M (2017) Effectiveness of bronchial thermoplasty in patients with severe refractory asthma: clinical and histopathologic correlations. J Allergy Clin Immunol 139:1176–1185 Facciolongo N, Di Stefano A, Pietrini V, Galeone C, Bellanova F, Menzella F, Scichilone N, Piro R, Bajocchi GL, Balbi B, Agostini L, Salsi PP, Formisano D, Lusuardi M (2018) Nerve ablation after bronchial thermoplasty and sustained improvement in severe asthma. BMC Pulm Med 18:29–017 Yamamura K, Hara J, Ohkura N, Abo M, Sone T, Kimura H, Kasahara K (2019) Increased cough receptor sensitivity to capsaicin predicts a positive bronchial thermoplasty response: a single-center retrospective study. J Bronchology Interv Pulmonol 26:137–141 Cox G, Thomson NC, Rubin AS, Niven RM, Corris PA, Siersted HC, Olivenstein R, Pavord ID, McCormack D, Chaudhuri R, Miller JD, Laviolette M, AIR Trial Study Group (2007) Asthma control during the year after bronchial thermoplasty. N Engl J Med 356:1327–1337 Castro M, Rubin AS, Laviolette M, Fiterman J, De Andrade LM, Shah PL, Fiss E, Olivenstein R, Thomson NC, Niven RM, Pavord ID, Simoff M, Duhamel DR, McEvoy C, Barbers R, Ten Hacken NH, Wechsler ME, Holmes M, Phillips MJ, Erzurum S, Lunn W, Israel E, Jarjour N, Kraft M, Shargill NS, Quiring J, Berry SM, Cox G, AIR2 Trial Study Group (2010) Effectiveness and safety of bronchial thermoplasty in the treatment of severe asthma: a multicenter, randomized, double-blind, sham-controlled clinical trial. Am J Respir Crit Care Med 181:116–124 Pavord ID, Cox G, Thomson NC, Rubin AS, Corris PA, Niven RM, Chung KF, Laviolette M, RISA Trial Study Group (2007) Safety and efficacy of bronchial thermoplasty in symptomatic, severe asthma. Am J Respir Crit Care Med 176:1185–1191 Kanemitsu Y, Takakuwa O, Fukumitsu K, Asano T, Niimi A (2018) Bronchial thermoplasty for severe asthmatic cough. Ann Intern Med 169:61–62 Taylor-Clark TE, Kiros F, Carr MJ, McAlexander MA (2009) Transient receptor potential ankyrin 1 mediates toluene diisocyanate-evoked respiratory irritation. Am J Respir Cell Mol Biol 40:756–762