Naphthalimides exhibit in vitro antiproliferative and antiangiogenic activities by inhibiting both topoisomerase II (topo II) and receptor tyrosine kinases (RTKs)

European Journal of Medicinal Chemistry - Tập 65 - Trang 477-486 - 2013
Xin Wang1, Zhuo Chen1,2, Linjiang Tong2, Shaoying Tan1, Wei Zhou1, Ting Peng2, Kun Han2, Jian Ding2, Hua Xie2, Yufang Xu1
1State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, Shanghai key Laboratory of New Drug Design, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
2Division of Anti-Tumor Pharmacology, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China

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