Nanomaterials in electrochemical biosensors for pesticide detection: advances and challenges in food analysis
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García-Cañas V, Simó C, Herrero M, Ibáñez E, Cifuentes A (2012) Present and future challenges in food analysis: Foodomics. Anal Chem 84:10150–10159
Scognamiglio V, Arduini F, Palleschi G, Rea G (2014) Biosensing technology for sustainable food safety. Trends Anal Chem 62:1–10
http://archive.epa.gov/pesticides/news/web/html/sales-usage06-07.html accessed on 29 January 2016
EU Dir. 2013/39/EC for inland surface waters
http://www.ecpa.eu/faq/what-maximum-residue-level-mrl-and-how-are-they-set accessed on 29 January 2016
JRC FORESIGHT STUDY of European Commission; Joint Research Centre Tomorrow’s Healthy Society Research Priorities for Foods and Diets 2014 Final Report; https://ec.europa.eu/jrc/sites/default/files/jrc-study-tomorrow-healthly-society.pdf accessed on 31 January 2016
Del Carlo M, Compagnone D (2010) Recent strategies for the biological sensing of pesticides: from the design to the application in real samples. Bioanal Rev 1:159–176
Rotariu L, Lagarde F, Jaffrezic-Renault N, Bala C (2016) Electrochemical biosensors for fast detection of food contaminants-trends and perspective. Trends Anal Chem. doi: 10.1016/j.trac.2015.12.017
Viswanathan S, Radecki J (2008) Nanomaterials in electrochemical biosensors for food analysis-a review. Pol J Food Nutr Sci 58:157–164
Scognamiglio V (2013) Nanotechnology in glucose monitoring: advances and challenges in the last 10 years. Biosens Bioelectron 47:12–25
Viswanathan S, Radecka H, Radecki J (2009) Electrochemical biosensors for food analysis. Monatsh Chem 140:891–899
Zhang L, Wang J, Tian Y (2014) Electrochemical in-vivo sensors using nanomaterials made from carbon species, noble metals, or semiconductors. Microchim Acta 181:1471–1484
Wu J, Zhu Y, Xue F, Mei Z, Yao L, Wang X, Zheng L, Liu J, Liu G, Peng C (2014) Recent trends in SELEX technique, and its application to food safety monitoring. Microchim Acta 181:479–491
Shi X, Gu W, Li B, Chen N, Zhao K, Xian Y (2014) Enzymatic biosensors based on the use of metal oxide nanoparticles. Microchim Acta 181:1–22 References 14 and 96 based on original manuscript we received were identical. Hence, the latter was deleted and reference list and citations were adjusted. Please check if appropriate.ok
Ju KJ, Feng JX, Feng JJ, Zhang QL, Xu TQ, Wei J, Wang AJ (2015) Biosensor for pesticide triazophos based on its inhibition of acetylcholinesterase and using a glassy carbon electrode modified with coral-like gold nanostructures supported on reduced graphene oxide. Microchim Acta 182:2427–2434
Wei M, Zeng G, Lu Q (2014) Determination of organophosphate pesticides using an acetylcholinesterase-based biosensor based on a boron-doped diamond electrode modified with gold nanoparticles and carbon spheres. Microchim Acta 181:121–127ok
Arduini F, Guidone S, Amine A, Palleschi G, Moscone D (2013) Acetylcholinesterase biosensor based on self-assembled monolayer-modified gold-screen printed electrodes for organophosphorus insecticide detection. Sens Actuat B 179:201–208
Liu S, Zheng Z, Li X (2013) Advances in pesticide biosensors: current status, challenges, and future perspectives. Anal Bioanal Chem 405:63–90
Pérez-López B, Merkoçi A (2011) Nanomaterials based biosensors for food analysis applications. Trends Food Sci Tech 22:625–639
Zheng Z, Zhou Y, Li X, Liu S, Tang Z (2011) Highly-sensitive organophosphorous pesticide biosensors based on nanostructured films of acetylcholinesterase and CdTe quantum dots. Biosens Bioelectron 26:3081–3085
Arduini F, Amine A, Moscone D, Palleschi G (2010) Biosensors based on cholinesterase inhibition for insecticides, nerve agents and aflatoxin B1 detection (review). Microchim Acta 170:193–214
Amine A, Arduini F, Moscone D, Palleschi G (2016) Recent advances in biosensors based on enzyme inhibition. Biosens Bioelectron 76:180–194
Andreescu S, Marty JL (2006) Twenty years research in cholinesterase biosensors: from basic research to practical applications. Biomol Eng 23:1–15
Periasamy AP, Umasankar Y, Chen SM (2009) Nanomaterials acetylcholinesterase enzyme matrices for organophosphorus pesticides electrochemical sensors:a review. Sensors 9:4034–4055
Benilova I, Arkhypova Dzydevych SV, Jaffrezic-Renault N, Martelet C, Soldatkin AP (2006) Kinetics of human and horse sera cholinesterases inhibition with solanaceous glycoalkaloids: study by potentiometric biosensor. Pestic Biochem Phys 86:203–210
Soldatkin OO, Burdak OS, Sergeyeva TA, Arkhypova VM, Dzyadevych SV, Soldatkin AP (2013) Acetylcholinesterase-based conductometric biosensor for determination of aflatoxin B1. Sens Actuat B 188:999–1003
Del Carlo M, Pepe A, Sergi M, Mascini M, Tarentini A, Compagnone D (2010) Detection of coumaphos in honey using a screening method based on an electrochemical acetylcholinesterase bioassay. Talanta 81:76–81
Cremisini C, Di Sario S, Mela J, Pilloton R, Palleschi G (1995) Evaluation of the use of free and immobilised acetylcholinesterase for paraoxon detection with an amperometric choline oxidase biosensor. Anal Chim Acta 311:273–280
Arduini F, Ricci F, Tuta CS, Moscone D, Amine A, Palleschi G (2006) Detection of carbammic and organophosphorus pesticides in water samples using cholinesterase biosensor based on Prussian blue modified screen printed electrode. Anal Chim Acta 580:155–162
Hernandez S, Palchetti I, Mascini M (2000) Determination of anticholinesterase activity for pesticides monitoring using a thiocholine sensor. Int J Environ Anal Chem 78:263–278
Lin YH, Lu F, Wang J (2004) Disposable carbon nanotube modified screen-printed biosensor for amperometric detection of organophosphorus pesticides and nerve agents. Electroanal 16:145–149
Hou S, Ou Z, Chen Q, Wu B (2012) Amperometric acetylcholine biosensor based on self-assembly of gold nanoparticles and acetylcholinesterase on the sol–gel/multi-walled carbon nanotubes/choline oxidase composite-modified platinum electrode. Biosens Bioelectron 33:44–49
Arduini F, Majorani C, Amine A, Moscone D, Palleschi G (2011) Hg2+ detection by measuring thiol groups with a highly sensitive screen-printed electrode modified with a nanostructured carbon black film. Electrochim Acta 56:4209–4215
Liu Q, Fei A, Huan J, Mao H, Wang K (2015) Effective amperometric biosensor for carbaryl detection based on covalent immobilization acetylcholinesterase on multiwall carbon nanotubes/graphene oxide nanoribbons nanostructure. J Electroanal Chem 740:8–13
Cesarino I, Moraes FC, Lanza MR, Machado SA (2012) Electrochemical detection of carbamate pesticides in fruit and vegetables with a biosensor based on acetylcholinesterase immobilised on a composite of polyaniline–carbon nanotubes. Food Chem 135:873–879
Zhang L, Zhang A, Du D, Lin Y (2012) Biosensor based on Prussian blue nanocubes/reduced graphene oxide nanocomposite for detection of organophosphorus pesticides. Nanoscale 4:4674–4679
Du D, Wang M, Cai J, Zhang A (2010) Sensitive acetylcholinesterase biosensor based on assembly of β-cyclodextrins onto multiwall carbon nanotubes for detection of organophosphates pesticide. Sens Actuators, B 146:337–341
Liu Y, Wang G, Li C, Zhou Q, Wang M, Yang L (2014) A novel acetylcholinesterase biosensor based on carboxylic graphene coated with silver nanoparticles for pesticide detection. Mater Sci Eng C 35:253–258
de Oliveira Marques PRB, Nunes GS, dos Santos TCR, Andreescu S, Marty JL (2004) Comparative investigation between acetylcholinesterase obtained from commercial sources and genetically modified Drosophila melanogaster: application in amperometric biosensors for methamidophos pesticide detection. Biosens Bioelectron 20:825–832
Arduini F, Neagu D, Scognamiglio V, Patarino S, Moscone D, Palleschi G (2015) Automatable flow system for paraoxon detection with an embedded screen-printed electrode tailored with butyrylcholinesterase and Prussian blue nanoparticles. Chemosensors 3:129–145
Arduini F, Palleschi G (2012) In Portable Chemical Sensors (pp. 261–278). In: Disposable electrochemical biosensor based on cholinesterase inhibition with improved shelf-life and working stability for nerve agent detection. Springer, Netherlands
Chauhan N, Pundir CS (2011) An amperometric biosensor based on acetylcholinesterase immobilized onto iron oxide nanoparticles/multi-walled carbon nanotubes modified gold electrode for measurement of organophosphorus insecticides. Anal Chim Acta 701:66–74
Bao J, Hou C, Chen M, Li J, Huo D, Yang M, Luo X, Lei Y (2015) Plant esterase-chitosan/gold nanoparticles–graphene nanosheet composite-based biosensor for the ultrasensitive detection of organophosphate pesticides. J Agric Food Chem 63:10319–10326
Haddaoui M, Raouafi N (2015) Chlortoluron-induced enzymatic activity inhibition in tyrosinase/ZnO NPs/SPCE biosensor for the detection of ppb levels of herbicide. Sens Actuat B 219:171–178
Arduini F, Amine A (2014) Biosensors based on enzyme inhibition. In Biosensors Based on Aptamers and Enzymes (pp. 299–326). Springer Berlin, Heidelberg
Tortolini C, Bollella P, Antiochia R, Favero G, Mazzei F (2016) Inhibition-based biosensor for atrazine detection. Sens Actuat B 224:552–558
Zapp E, Brondani D, Vieira IC, Scheeren CW, Dupont J, Barbosa AM, Ferreira VS (2011) Biomonitoring of methomyl pesticide by laccase inhibition on sensor containing platinum nanoparticles in ionic liquid phase supported in montmorillonite. Sens Actuat B 155:331–339
Ribeiro FWP, Barroso MF, Morais S, Viswanathan S, de Lima-Neto P, Correia AN, Oliveira ABPP, Delerue-Matos C (2014) Simple laccase-based biosensor for formetanate hydrochloride quantification in fruits. Bioelectrochem 95:7–14
Lee JH, Park JY, Min K, Cha HJ, Choi SS, Yoo, YJ (2010) A novel organophosphorus hydrolase-based biosensor using mesoporous carbons and carbon black for the detection of organophosphate nerve agents. Biosens Bioelectron 25:1566–1570
Chen S, Huang J, Du D, Li J, Tu H, Liu D, Zhang A (2011) Methyl parathion hydrolase based nanocomposite biosensors for highly sensitive and selective determination of methyl parathion. Biosens Bioelectron 26:4320–4325
Tang J, Tang D (2015) Non-enzymatic electrochemical immunoassay using noble metal nanoparticles: a review. Microchim Acta 182:2077–2089
Valera E, García-Febrero R, Pividori I, Sánchez-Baeza F, Marco MP (2014) Coulombimetric immunosensor for paraquat based on electrochemical nanoprobes. Sens Actuat B 194:353–360
Dai Z, Liu H, Shen Y, Su X, Xu Z, Sun Y, Zou X (2012) Attomolar determination of coumaphos by electrochemical displacement immunoassay coupled with oligonucleotide sensing. Anal Chem 84:8157–8163
Liu G, Guo W, Song D (2014) A multianalyte electrochemical immunosensor based on patterned carbon nanotubes modified substrates for detection of pesticides. Biosens Bioelectron 52:360–366
Sun X, Zhu Y, Wang X (2012) Amperometric immunosensor based on deposited gold nanocrystals/4, 4′-thiobisbenzenethiol for determination of carbofuran. Food Control 28:184–191
Scognamiglio V, Antonacci A, Lambreva MD, Litescu SC, Rea G (2015) Synthetic biology and biomimetic chemistry as converging technologies fostering a new generation of smart biosensors. Biosens Bioelectron 74:1076–1086
Sassolas A, Prieto-Simón B, Marty J-L (2012) Biosensors for pesticide detection: new trends. Am J Anal Chem 3:210–232
He J, Liu Y, Fan M, Liu X (2011) Isolation and identification of the DNA aptamer target to acetamiprid. J Agric Food Chem 59:1582–1586
Fan L, Zhao G, Shi H, Liu M, Li Z (2013) A highly selective electrochemical impedance spectroscopy-based aptasensor for sensitive detection of acetamiprid. Biosens Bioelectron 43:12–18
Fei A, Liu Q, Huan J, Qian J, Dong X, Qiu B, Mao H, Wang K (2015) Label-free impedimetric aptasensor for detection of femtomole level acetamiprid using gold nanoparticles decorated multiwalled carbon nanotube-reduced graphene oxide nanoribbon composites. Biosens Bioelectron 70:122–129
Oliveira TMBF, Barroso MF, Morais S, de Lima-Neto P, Correia AN, Oliveira MBPP, Delerue-Matos C (2013) Biosensor based on multi-walled carbon nanotubes paste electrode modified with laccase for pirimicarb pesticide quantification. Talanta 106:137–143
Du D, Ye X, Cai J, Liu J, Zhang A (2010) Acetylcholinesterase biosensor design based on carbon nanotube-encapsulated polypyrrole and polyaniline copolymer for amperometric detection of organophosphates. Biosens Bioelectron 25:2503–2508
Çevik S, Timur S, Anik Ü (2013) Poly (allylamine hydrochloride) functionalized multiwalled carbon nanotube modified carbon paste electrode as acetylcholinesterase biosensor transducer. Electroanal 25:2377–2383
Zhai C, Sun X, Zhao W, Gong Z, Wang X (2013) Acetylcholinesterase biosensor based on chitosan/prussian blue/multiwall carbon nanotubes/hollow gold nanospheres nanocomposite film by one-stepelectrodeposition. Biosens Bioelectron 42:124–130
Sun X, Cao Y, Gong Z, Wang X, Zhang Y, Gao J (2012) An amperometric immunosensor based on multi-walled carbon nanotubes-thionine-chitosan nanocomposite film for chlorpyrifos detection. Sensors 12:17247–17261
Chen D, Jiao Y, Jia H, Guo Y, Sun X, Wang X, Xu J (2015) Acetylcholinesterase biosensor for chlorpyrifos detection based on multi-walled carbon nanotubes-SnO2-chitosan nanocomposite modified screen-printed electrode. Int J Electrochem Sci 10:10491–10501
Khaled E, Kamel MS, Hassan HNA, Abdel-Gawad H, Aboul-Enein HY (2014) Performance of a portable biosensor for the analysis of ethion residues. Talanta 119:467–472
Kesik M, Kanik FE, Turan J, Kolb M, Timur S, Bahadir M, Toppare L (2014) An acetylcholinesterase biosensor based on a conducting polymer using multiwalled carbon nanotubes for amperometric detection of organophosphorous pesticides. Sens Actuat B 205:39–49
Gan N, Yang X, Xie D, Wu Y, Wen W (2010) A disposable organophosphorus pesticides enzyme biosensor based on magnetic composite nano-particles modified screen printed carbon electrode. Sensors 10:625–638
Ivanov AN, Younusov RR, Evtugyn GA, Arduini F, Moscone D, Palleschi G (2011) Acetylcholinesterase biosensor based on single-walled carbon nanotubes—Co phtalocyanine for organophosphorus pesticides detection. Talanta 85:216–221
Liu G, Wang S, Liu J, Song D (2012) An electrochemical immunosensor based on chemical assembly of vertically aligned carbon nanotubes on carbon substrates for direct detection of the pesticide endosulfan in environmental water. Anal Chem 84:3921–3928
Zheng Y, Liu Z, Jing Y, Li J, Zhan H (2015) An acetylcholinesterase biosensor based on ionic liquid functionalized graphene–gelatin-modified electrode for sensitive detection of pesticides. Sens Actuat B 210:389–397
Oliveira TM, Barroso MF, Morais S, Araújo M, Freire C, de Lima-Neto P, Correia AN, Oliveira MBPP, Delerue-Matos C (2014) Sensitive bi-enzymatic biosensor based on polyphenoloxidases–gold nanoparticles–chitosan hybrid film–graphene doped carbon paste electrode for carbamates detection. Bioelectrochem 98:20–29
Zhang Y, Liu H, Yang Z, Ji S, Wang J, Pang P, Feng L, Wang H, Wu Z, Yang W (2015) An acetylcholinesterase inhibition biosensor based on a reduced graphene oxide/silver nanocluster/chitosan nanocomposite for detection of organophosphorus pesticides. Anal Methods 7:6213–6219
Yang Y, Asiri AM, Du D, Lin Y (2014) Acetylcholinesterase biosensor based on a gold nanoparticle–polypyrrole–reduced graphene oxide nanocomposite modified electrode for the amperometric detection of organophosphorus pesticides. Analyst 139:3055–3060
Wang G, Tan X, Zhou Q, Liu Y, Wang M, Yang L (2014) Synthesis of highly dispersed zinc oxide nanoparticles on carboxylic graphene for development a sensitive acetylcholinesterase biosensor. Sens Actuat B 190:730–736
Yang L, Wang G, Liu Y, Wang M (2013) Development of a biosensor based on immobilization of acetylcholinesterase on NiO nanoparticles–carboxylic graphene–nafion modified electrode for detection of pesticides. Talanta 113:135–141
Zhou Q, Yang L, Wang G, Yang Y (2013) Acetylcholinesterase biosensor based on SnO2 nanoparticles–carboxylic graphene–nafion modified electrode for detection of pesticides. Biosens Bioelectron 49:25–31
Wang K, Liu Q, Dai L, Yan J, Ju C, Qiu B, Wu X (2011) A highly sensitive and rapid organophosphate biosensor based on enhancement of CdS–decorated graphene nanocomposite. Anal Chim Acta 695:84–88
Li X, Zheng Z, Liu X, Zhao S, Liu S (2015) Nanostructured photoelectrochemical biosensor for highly sensitive detection of organophosphorous pesticides. Biosens Bioelectron 64:1–5
Arduini F, Amine A, Majorani C, Di Giorgio F, De Felicis D, Cataldo F, Moscone D, Palleschi G (2010) High performance electrochemical sensor based on modified screen-printed electrodes with cost-effective dispersion of nanostructured carbon black. Electrochem Comm 31:346–350
Lo TW, Aldous L, Compton RG (2012) The use of nano-carbon as an alternative to multi-walled carbon nanotubes in modified electrodes for adsorptive stripping voltammetry. Sens Actuat B 162:361–368
Cinti S, Arduini F, Carbone M, Sansone L, Cacciotti I, D. M, Palleschi G (2015) Screen-printed electrodes modified with carbon nanomaterials: a comparison among carbon black, carbon nanotubes and graphene. Electroanal 27:2230–2238
Vicentini FC, Ravanini AE, Figueiredo-Filho LC, Iniesta J, Banks CE, Fatibello-Filho O (2015) Imparting improvements in electrochemical sensors: evaluation of different carbon blacks that give rise to significant improvement in the performance of electroanalytical sensing platforms. Electrochim Acta 157:125–133
Arduini F, Forchielli M, Amine A, Neagu D, Cacciotti I, Nanni F, Moscone D, Palleschi G (2015) Screen-printed biosensor modified with carbon black nanoparticles for the determination of paraoxon based on the inhibition of butyrylcholinesterase. Microchim Acta 182:643–651
Jeyapragasam T, Saraswathi R (2014) Electrochemical biosensing of carbofuran based on acetylcholinesterase immobilized onto iron oxide–chitosan nanocomposite. Sens Actuat B 191:681–687
Evtugyn GA, Shamagsumova RV, Padnya PV, Stoikov II, Antipin IS (2014) Cholinesterase sensor based on glassy carbon electrode modified with Ag nanoparticles decorated with macrocyclic ligands. Talanta 127:9–17
Shamagsumova RV, Shurpik DN, Padnya PL, Stoikov II, Evtugyn GA (2015) Acetylcholinesterase biosensor for inhibitor measurements based on glassy carbon electrode modified with carbon black and pillar [5] arene. Talanta 144:559–568
Wei M, Wang J (2015) A novel acetylcholinesterase biosensor based on ionic liquids-AuNPs-porous carbon composite matrix for detection of organophosphate pesticides. Sens Actuat B 211:290–296
Liu Y, Wei M (2014) Development of acetylcholinesterase biosensor based on platinum–carbon aerogels composite for determination of organophosphorus pesticides. Food Control 36:49–54
Wang J (2012) Electrochemical biosensing based on noble metal nanoparticles. Microchim Acta 177:245–270
Vertegel AA, Siegel RW, Dordick JS (2004) Silica nanoparticle size influences the structure and enzymatic activity of adsorbed lysozyme. Langmuir 20:6800–6807
Roach P, Farrar D, Perry CC (2006) Surface tailoring for controlled protein adsorption: effect of topography at the nanometer scale and chemistry. J Am Chem Soc 128:3939–3945
Pichetsurnthorn P, Vattipalli K, Prasad S (2012) Nanoporous impedemetric biosensor for detection of trace atrazine from water samples. Biosens Bioelectron 32:155–162
Wei W, Zong X, Wang X, Yin L, Pu Y, Liu S (2012) A disposable amperometric immunosensor for chlorpyrifos-methyl based on immunogen/platinum doped silica sol–gel film modified screen-printed carbon electrode. Food Chem 135:888–892
Nesakumar N, Sethuraman S, Krishnan UM, Rayappan JBB (2015) Cyclic voltammetric acetylcholinesterase biosensor for the detection of captan in apple samples with the aid of chemometrics. Anal Bioanal Chem 407:1–6
Nesakumar N, Sethuraman S, Krishnan UM, Rayappan JBB (2016) Electrochemical acetylcholinesterase biosensor based on ZnO nanocuboids modified platinum electrode for the detection of carbosulfan in rice. Biosens Bioelectron 77:1070–1077
Wu S, Lan X, Zhao W, Li Y, Zhang L, Wang H, Han M, Tao S (2011) Controlled immobilization of acetylcholinesterase on improved hydrophobic gold nanoparticle/Prussian blue modified surface for ultra-trace organophosphate pesticide detection. Biosens Bioelectron 27:82–87
Du D, Chen S, Cai J, Zhang A (2007) Immobilization of acetylcholinesterase on gold nanoparticles embedded in sol-gel film for amperometric detection of organophosphorous insecticide. Biosens Bioelectron 23:130–134
Turan J, Kesik M, Soylemez S, Goker S, Coskun S, Unalan HE, Toppare L (2016) An effective surface design based on a conjugated polymer and silver nanowires for the detection of paraoxon in tap water and milk. Sens Actuat B 228:278–286
Wu S, Zhang L, Qi L, Tao S, Lan X, Liu Z, Meng C (2011) Ultra-sensitive biosensor based on mesocellular silica foam for organophosphorous pesticide detection. Biosens Bioelectron 26:2864–2869
Liu X, Li WJ, Li L, Yang Y, Mao LG (2014) Peng Z. A label-free electrochemical immunosensor based on gold nanoparticles for direct detection of atrazine Sens Actuat B 191:408–414
Jia H, Guo Y, Sun X, Wang X (2015) An electrochemical immunosensor based on microfluidic Chip for detection of chlorpyrifos. Int J Electrochem Sci 10:8750–8758
Jin B, Xie L, Guo Y, Pang G (2012) Multi-residue detection of pesticides in juice and fruit wine: a review of extraction and detection methods. Food Res Int 46:399–409
Anastassiades M, Lehotay J, Štajnbaher D, Schenck FJ (2003) Fast and easy multiresidue method employing acetonitrile extraction/partitioning and “dispersive solid-phase extraction” for the determination of pesticide residues in produce. J AOAC Int 86:412–431
Wilkowska A, Biziuk M (2011) Determination of pesticide residues in food matrices using the QuEChERS methodology. Food Chem 125:803–812
European Council Directive 2002/63/CE, Establishing community methods of sampling for the official control of pesticide residues in and on products of plant and animal origin and repealing Directive 79/700/EEC. Off, J. Eur. Communities (2002) L187/30–31
D’Ilio S, Petrucci F, D’Amato M, Di Gregorio M, Senofonte O, Violante N (2008) Method validation for determination of arsenic, cadmium, chromium and lead in milk by means of dynamic reaction cell inductively coupled plasma mass spectrometry. Anal Chim Acta 624:59–67
Arduini F, Micheli L, Moscone D, Palleschi G, Piermarini S, Ricci F, Volpe G (2016) Electrochemical biosensors based on nanomodified screen-printed electrodes: recent applications in clinical analysis. TrAC Trends Anal Chem in press. doi: 10.1016/j.trac.2016.01.032
Crew A, Lonsdale D, Byrd N, Pittson R, Hart JP (2011) A screen-printed, amperometric biosensor array incorporated into a novel automated system for the simultaneous determination of organophosphate pesticides. Biosens Bioelectron 26:2847–2851