NF-κB is required for dengue virus NS5-induced RANTES expression

Ashour, 2009, NS5 of dengue virus mediates STAT2 binding and degradation, J. Virol., 83, 5408, 10.1128/JVI.02188-08 Ashour, 2009, Mouse STAT2 restricts early dengue virus replication, Cell Host Microbe, 8, 410, 10.1016/j.chom.2010.10.007 Avirutnan, 1998, Dengue virus infection of human endothelial cells leads to chemokine production, complement activation, and apoptosis, J. Immunol., 161, 6338, 10.4049/jimmunol.161.11.6338 Barreto, 2004, Histopathological aspects of Dengue-2 virus infected mice tissues and complementary virus isolation, J. Submicrosc Cytol. Pathol., 36, 121 Bashyam, 2006, Dengue virus-reactive CD8+ T cells display quantitative and qualitative differences in their response to variant epitopes of heterologous viral serotypes, J. Immunol., 176, 2817, 10.4049/jimmunol.176.5.2817 Becquart, 2010, Acute dengue virus 2 infection in Gabonese patients is associated with an early innate immune response, including strong interferon alpha production, BMC Infect. Dis., 10, 356, 10.1186/1471-2334-10-356 Boonnak, 2008, Role of dendritic cells in antibody-dependent enhancement of dengue virus infection, J. Virol., 82, 3939, 10.1128/JVI.02484-07 Boonpucknavig, 1981, Infection of young adult mice with dengue virus type 2, Trans. R. Soc. Trop. Med. Hyg., 75, 647, 10.1016/0035-9203(81)90142-5 Bozza, 2008, Multiplex cytokine profile from dengue patients: MIP-1beta and IFN-gamma as predictive factors for severity, BMC Infect. Dis., 8, 86, 10.1186/1471-2334-8-86 Casola, 2002, Regulation of RANTES promoter activation in alveolar epithelial cells after cytokine stimulation, Am. J. Physiol. Lung Cell Mol. Physiol., 283, L1280, 10.1152/ajplung.00162.2002 Chang, 2012, Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-kappaB activation to downregulate cytokine production, PLoS ONE, 7, e41635, 10.1371/journal.pone.0041635 Chen, 2008, CLEC5A is critical for dengue-virus-induced lethal disease, Nature, 453, 672, 10.1038/nature07013 Chua, 2005, Recombinant non-structural 1 (NS1) protein of dengue-2 virus interacts with human STAT3beta protein, Virus Res., 112, 85, 10.1016/j.virusres.2005.03.025 Costa, 2013, Inflammatory and innate immune responses in dengue infection: protection versus disease induction, Am. J. Pathol., 182, 1950, 10.1016/j.ajpath.2013.02.027 de-Oliveira-Pinto, 2012, Regulation of inflammatory chemokine receptors on blood T cells associated to the circulating versus liver chemokines in dengue fever, PLoS ONE, 7, e38527, 10.1371/journal.pone.0038527 De Bosscher, 2005, A fully dissociated compound of plant origin for inflammatory gene repression, Proc. Natl. Acad. Sci. U.S.A., 102, 15827, 10.1073/pnas.0505554102 Dewint, 2008, A plant-derived ligand favoring monomeric glucocorticoid receptor conformation with impaired transactivation potential attenuates collagen-induced arthritis, J. Immunol., 180, 2608, 10.4049/jimmunol.180.4.2608 Fink, 2007, Host gene expression profiling of dengue virus infection in cell lines and patients, PLoS Negl. Trop. Dis., 1, e86, 10.1371/journal.pntd.0000086 Genin, 2000, Regulation of RANTES chemokine gene expression requires cooperativity between NF-kappa B and IFN-regulatory factor transcription factors, J. Immunol., 164, 5352, 10.4049/jimmunol.164.10.5352 Gentry, 1982, Identification of distinct antigenic determinants on dengue-2 virus using monoclonal antibodies, Am. J. Trop. Med. Hyg., 31, 548, 10.4269/ajtmh.1982.31.548 Gerondakis, 2014, NF-kappaB control of T cell development, Nat. Immunol., 15, 15, 10.1038/ni.2785 Gilmore, 2006, Introduction to NF-kappaB: players, pathways, perspectives, Oncogene, 25, 6680, 10.1038/sj.onc.1209954 Green, 2014, Innate immunity to dengue virus infection and subversion of antiviral responses, J. Mol. Biol., 426, 1148, 10.1016/j.jmb.2013.11.023 Gubler, 1998, Dengue and dengue hemorrhagic fever, Clin. Microbiol. Rev., 11, 480, 10.1128/CMR.11.3.480 Halstead, 1988, Pathogenesis of dengue: challenges to molecular biology, Science, 239, 476, 10.1126/science.3277268 Halstead, 2007, Dengue, Lancet, 370, 1644, 10.1016/S0140-6736(07)61687-0 Heeger, 1992, Isolation and characterization of cDNA from renal tubular epithelium encoding murine Rantes, Kidney Int., 41, 220, 10.1038/ki.1992.31 Huang, 2000, Dengue virus infects human endothelial cells and induces IL-6 and IL-8 production, Am. J. Trop. Med. Hyg., 63, 71, 10.4269/ajtmh.2000.63.71 Jan, 2000, Potential dengue virus-triggered apoptotic pathway in human neuroblastoma cells: arachidonic acid, superoxide anion, and NF-kappaB are sequentially involved, J. Virol., 74, 8680, 10.1128/JVI.74.18.8680-8691.2000 Jiang, 2010, Identification of five interferon-induced cellular proteins that inhibit west nile virus and dengue virus infections, J. Virol., 84, 8332, 10.1128/JVI.02199-09 Kelley, 2012, Dengue hemorrhagic fever-associated immunomediators induced via maturation of dengue virus nonstructural 4B protein in monocytes modulate endothelial cell adhesion molecules and human microvascular endothelial cells permeability, Virology, 422, 326, 10.1016/j.virol.2011.10.030 Kelley, 2011, Maturation of dengue virus nonstructural protein 4B in monocytes enhances production of dengue hemorrhagic fever-associated chemokines and cytokines, Virology, 418, 27, 10.1016/j.virol.2011.07.006 Khunchai, 2012, Interaction of dengue virus nonstructural protein 5 with Daxx modulates RANTES production, Biochem. Biophys. Res. Commun., 423, 398, 10.1016/j.bbrc.2012.05.137 Laoprasopwattana, 2010, Outcome of dengue hemorrhagic fever-caused acute kidney injury in Thai children, J. Pediatr., 157, 303, 10.1016/j.jpeds.2010.02.008 Lee, 2009, Clinical characteristics, risk factors, and outcomes in adults experiencing dengue hemorrhagic fever complicated with acute renal failure, Am. J. Trop. Med. Hyg., 80, 651, 10.4269/ajtmh.2009.80.651 Lee, 2007, Dengue viruses can infect human primary lung epithelia as well as lung carcinoma cells, and can also induce the secretion of IL-6 and RANTES, Virus Res., 126, 216, 10.1016/j.virusres.2007.03.003 Lin, 2000, Involvement of oxidative stress, NF-IL-6, and RANTES expression in dengue-2-virus-infected human liver cells, Virology, 276, 114, 10.1006/viro.2000.0524 Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(−Delta Delta C(T)) Method, Methods, 25, 402, 10.1006/meth.2001.1262 Lizarraga, 2014, Dengue-associated kidney disease, J. Nephropathol., 3, 57 Marianneau, 1997, Dengue virus replication in human hepatoma cells activates NF-kappaB which in turn induces apoptotic cell death, J. Virol., 71, 3244, 10.1128/JVI.71.4.3244-3249.1997 Mazzon, 2009, Dengue virus NS5 inhibits interferon-alpha signaling by blocking signal transducer and activator of transcription 2 phosphorylation, J. Infect. Dis., 200, 1261, 10.1086/605847 Medin, 2005, Dengue virus nonstructural protein NS5 induces interleukin-8 transcription and secretion, J. Virol., 79, 11053, 10.1128/JVI.79.17.11053-11061.2005 Medin, 2006, Cell type-specific mechanisms of interleukin-8 induction by dengue virus and differential response to drug treatment, J. Infect. Dis., 193, 1070, 10.1086/502630 Mehra, 2012, Acute kidney injury in dengue fever using Acute Kidney Injury Network criteria: incidence and risk factors, Trop. Doct., 42, 160, 10.1258/td.2012.120023 Moreno-Altamirano, 2004, Gene expression in human macrophages infected with dengue virus serotype-2, Scand. J. Immunol., 60, 631, 10.1111/j.0300-9475.2004.01519.x Morrison, 2012, Innate immunity evasion by Dengue virus, Viruses, 4, 397, 10.3390/v4030397 Netsawang, 2014, Dengue virus disrupts Daxx and NF-kappaB interaction to induce CD137-mediated apoptosis, Biochem. Biophys. Res. Commun., 450, 1485, 10.1016/j.bbrc.2014.07.016 Palmer, 2005, Differential effects of dengue virus on infected and bystander dendritic cells, J. Virol., 79, 2432, 10.1128/JVI.79.4.2432-2439.2005 Pryor, 2007, Nuclear localization of dengue virus nonstructural protein 5 through its importin alpha/beta-recognized nuclear localization sequences is integral to viral infection, Traffic, 8, 795, 10.1111/j.1600-0854.2007.00579.x Rawlinson, 2009, CRM1-mediated nuclear export of dengue virus RNA polymerase NS5 modulates interleukin-8 induction and virus production, J. Biol. Chem., 284, 15589, 10.1074/jbc.M808271200 Reber, 2012, A dissociated glucocorticoid receptor modulator reduces airway hyperresponsiveness and inflammation in a mouse model of asthma, J. Immunol., 188, 3478, 10.4049/jimmunol.1004227 Silva, 2011, The dengue virus nonstructural protein 1 (NS1) increases NF-kappaB transcriptional activity in HepG2 cells, Arch. Virol., 156, 1275, 10.1007/s00705-011-0969-0 Suksanpaisan, 2007, Infection of human primary hepatocytes with dengue virus serotype 2, J. Med. Virol., 79, 300, 10.1002/jmv.20798 Suttitheptumrong, 2013, Compound A, a dissociated glucocorticoid receptor modulator, reduces dengue virus-induced cytokine secretion and dengue virus production, Biochem. Biophys. Res. Commun., 436, 283, 10.1016/j.bbrc.2013.05.094 Thomas, 1998, Respiratory syncytial virus-induced RANTES production from human bronchial epithelial cells is dependent on nuclear factor-kappa B nuclear binding and is inhibited by adenovirus-mediated expression of inhibitor of kappa B alpha, J. Immunol., 161, 1007, 10.4049/jimmunol.161.2.1007 Ubol, 2008, Clinical isolates of dengue virus with distinctive susceptibility to nitric oxide radical induce differential gene responses in THP-1 cells, Virology, 376, 290, 10.1016/j.virol.2008.03.030 Wati, 2007, Dengue virus (DV) replication in monocyte-derived macrophages is not affected by tumor necrosis factor alpha (TNF-alpha), and DV infection induces altered responsiveness to TNF-alpha stimulation, J. Virol., 81, 10161, 10.1128/JVI.00313-07 Wati, 2011, J. Gen. Virol., 92, 807, 10.1099/vir.0.028159-0