NF-κB and STAT3 cooperatively induce IL6 in starved cancer cells
Tóm tắt
Từ khóa
Tài liệu tham khảo
Ba X, Gupta S, Davidson M, Garg NJ . (2010). Trypanosoma cruzi induces the reactive oxygen species-PARP-1-RelA pathway for up-regulation of cytokine expression in cardiomyocytes. J Biol Chem 285: 11596–11606.
Bosco N, Pelliccia F, Rocchi A . (2010). Characterization of FRA7B, a human common fragile site mapped at the 7p chromosome terminal region. Cancer Genet Cytogenet 202: 47–52.
Deng J, Lu PD, Zhang Y, Scheuner D, Kaufman RJ, Sonenberg N et al. (2004). Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2. Mol Cell Biol 24: 10161–10168.
Frank DA . (2003). STAT signaling in cancer: insights into pathogenesis and treatment strategies. Cancer Treat Res 115: 267–291.
Franken NA, Rodermond HM, Stap J, Haveman J, van Bree C . (2006). Clonogenic assay of cells in vitro. Nat Protoc 1: 2315–2319.
Fujita T, Nolan GP, Ghosh S, Baltimore D . (1992). Independent modes of transcriptional activation by the p50 and p65 subunits of NF-kappa B. Genes Dev 6: 775–787.
Gil-Bazo I, Catalan V, Paramo J, Quero C, Escriva de Romani S, Perez-Ochoa A et al. (2003). Von Willebrand factor as an intermediate between hemostasis and angiogenesis of tumor origin. Rev Med Univ Navarra 47: 22–28.
Gloire G, Charlier E, Rahmouni S, Volanti C, Chariot A, Erneux C et al. (2006). Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappa B activation pathway and cellular survival upon oxidative stress. Oncogene 25: 5485–5494.
Gorlach A, Klappa P, Kietzmann T . (2006). The endoplasmic reticulum: folding, calcium homeostasis, signaling, and redox control. Antioxid Redox Signal 8: 1391–1418.
Grivennikov SI, Karin M . (2009). Dangerous liaisons: STAT3 and NF-kappa B collaboration and crosstalk in cancer. Cytokine Growth Factor Rev 21: 11–19.
Groner B, Lucks P, Borghouts C . (2008). The function of Stat3 in tumor cells and their microenvironment. Semin Cell Dev Biol 19: 341–350.
Hoyer-Hansen M, Jaattela M . (2007). Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium. Cell Death Differ 14: 1576–1582.
Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH . (2006). Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappa B activation and down-regulation of TRAF2 expression. Mol Cell Biol 26: 3071–3084.
Iliopoulos D, Hirsch HA, Struhl K . (2009). An epigenetic switch involving NF-kappa B, Lin28, Let-7 microRNA, and IL6 links inflammation to cell transformation. Cell 139: 693–706.
Jacobsen J, Wewer UM . (2009). Targeting ADAM12 in human disease: head, body or tail? Curr Pharm Des 15: 2300–2310.
Jiang HY, Wek RC . (2005). GCN2 phosphorylation of eIF2 alpha activates NF-kappa B in response to UV irradiation. Biochem J 385 (Pt 2): 371–380.
Kamata H, Honda S, Maeda S, Chang L, Hirata H, Karin M . (2005). Reactive oxygen species promote TNF alpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases. Cell 120: 649–661.
Kang MJ, Ryu BK, Lee MG, Han J, Lee JH, Ha TK et al. (2008). NF-kappa B activates transcription of the RNA-binding factor HuR, via PI3K-AKT signaling, to promote gastric tumorigenesis. Gastroenterology 135: 2030–2042 2042 e2031-2033.
Khabar KS . (2010). Post-transcriptional control during chronic inflammation and cancer: a focus on AU-rich elements. Cell Mol Life Sci 67: 2937–2955.
Kilberg MS, Shan J, Su N . (2009). ATF4-dependent transcription mediates signaling of amino acid limitation. Trends Endocrinol Metab 20: 436–443.
Kitamura M . (2009). Biphasic, bidirectional regulation of NF-kappa B by endoplasmic reticulum stress. Antioxid Redox Signal 11: 2353–2364.
Lee H, Herrmann A, Deng JH, Kujawski M, Niu G, Li Z et al. (2009). Persistently activated Stat3 maintains constitutive NF-kappa B activity in tumors. Cancer Cell 15: 283–293.
Lee JK, Edderkaoui M, Truong P, Ohno I, Jang KT, Berti A et al. (2007). NADPH oxidase promotes pancreatic cancer cell survival via inhibiting JAK2 dephosphorylation by tyrosine phosphatases. Gastroenterology 133: 1637–1648.
Li J, Ni M, Lee B, Barron E, Hinton DR, Lee AS . (2008). The unfolded protein response regulator GRP78/BiP is required for endoplasmic reticulum integrity and stress-induced autophagy in mammalian cells. Cell Death Differ 15: 1460–1471.
Lin JH, Li H, Yasumura D, Cohen HR, Zhang C, Panning B et al. (2007). IRE1 signaling affects cell fate during the unfolded protein response. Science 318: 944–949.
Marciniak SJ, Ron D . (2006). Endoplasmic reticulum stress signaling in disease. Physiol Rev 86: 1133–1149.
Mattarollo SR, Smyth MJ . (2010). A novel axis of innate immunity in cancer. Nat Immunol 11: 981–982.
Murray PJ . (2007). The JAK-STAT signaling pathway: input and output integration. J Immunol 178: 2623–2629.
Oyadomari S, Mori M . (2004). Roles of CHOP/GADD153 in endoplasmic reticulum stress. Cell Death Differ 11: 381–389.
Pahl HL, Baeuerle PA . (1996). Activation of NF-kappa B by ER stress requires both Ca2+ and reactive oxygen intermediates as messengers. FEBS Lett 392: 129–136.
Shang J, Lehrman MA . (2004). Inhibition of mammalian RNA synthesis by the cytoplasmic Ca2+ buffer BAPTA. Analyses of [3H]uridine incorporation and stress-dependent transcription. Biochemistry 43: 9576–9582.
Silvera D, Formenti SC, Schneider RJ . (2010). Translational control in cancer. Nat Rev Cancer 10: 254–266.
Smyth I, Du X, Taylor MS, Justice MJ, Beutler B, Jackson IJ . (2004). The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci USA 101: 13560–13565.
Souza V, Escobar Mdel C, Bucio L, Hernandez E, Gomez-Quiroz LE, Gutierrez Ruiz MC . (2009). NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. Toxicol Lett 187: 180–186.
Vales LD, Friedl EM . (2002). Binding of C/EBP and RBP (CBF1) to overlapping sites regulates interleukin-6 gene expression. J Biol Chem 277: 42438–42446.
Wu TY, Hsieh CC, Hong JJ, Chen CY, Tsai YS . (2009). IRSS: a web-based tool for automatic layout and analysis of IRES secondary structure prediction and searching system in silico. BMC Bioinform 10: 160.
Xiao G, Fu J . (2011). NF-κB and cancer: a paradigm of Yin-Yang. Am J Cancer Res 1: 192–221.
Yang J, Liao X, Agarwal MK, Barnes L, Auron PE, Stark GR . (2007). Unphosphorylated STAT3 accumulates in response to IL-6 and activates transcription by binding to NF kappa B. Genes Dev 21: 1396–1408.
Yang XR, Pfeiffer RM, Wheeler W, Yeager M, Chanock S, Tucker MA et al. (2009). Identification of modifier genes for cutaneous malignant melanoma in melanoma-prone families with and without CDKN2A mutations. Int J Cancer 125: 2912–2917.
Ye J, Cippitelli M, Dorman L, Ortaldo JR, Young HA . (1996). The nuclear factor YY1 suppresses the human gamma interferon promoter through two mechanisms: inhibition of AP1 binding and activation of a silencer element. Mol Cell Biol 16: 4744–4753.
Ye J, Kumanova M, Hart LS, Sloane K, Zhang H, De Panis DN et al. (2010). The GCN2-ATF4 pathway is critical for tumour cell survival and proliferation in response to nutrient deprivation. EMBO J 29: 2082–2096.
Yoon S, Woo SU, Kang JH, Kim K, Kwon MH, Park S et al. (2010). STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells. Autophagy 6: 1125–1138.
Yu H, Jove R . (2004). The STATs of cancer—new molecular targets come of age. Nat Rev Cancer 4: 97–105.