N-Acetylaspartylglutamate (NAAG) and N-Acetylaspartate (NAA) in Patients With Schizophrenia
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Paz, 2008, Glutamatergic dysfunction in schizophrenia: from basic neuroscience to clinical psychopharmacology, Eur Neuropsychopharmacol, 18, 773, 10.1016/j.euroneuro.2008.06.005
Patil, 2007, Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial, Nat Med, 13, 1102, 10.1038/nm1632
Wroblewska, 1997, N-acetylaspartylglutamate selectively activates mGluR3 receptors in transfected cells, J Neurochem, 69, 174, 10.1046/j.1471-4159.1997.69010174.x
Cartmell, 1998, Characterization of [3H]-(2S,2'R,3'R)-2-(2',3'-dicarboxy-cyclopropyl)glycine ([3H]-DCG IV) binding to metabotropic mGlu2 receptor-transfected cell membranes, Br J Pharmacol, 123, 497, 10.1038/sj.bjp.0701647
Olszewski, 2004, NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR, J Neurochem, 89, 876, 10.1111/j.1471-4159.2004.02358.x
Olszewski, 2008, Phencyclidine and dizocilpine induced behaviors reduced by N-acetylaspartylglutamate peptidase inhibition via metabotropic glutamate receptors, Biol Psychiatry, 63, 86, 10.1016/j.biopsych.2007.04.016
Zhou, 2005, NAAG peptidase inhibitors and their potential for diagnosis and therapy, Nat Rev Drug Discov, 4, 1015, 10.1038/nrd1903
Tsai, 1995, Abnormal excitatory neurotransmitter metabolism in schizophrenic brains, Arch Gen Psychiatry, 52, 829, 10.1001/archpsyc.1995.03950220039008
Nudmamud, 2003, N-acetylaspartate and N-Acetylaspartylglutamate deficits in superior temporal cortex in schizophrenia and bipolar disorder: a postmortem study, Biol Psychiatry, 53, 1138, 10.1016/S0006-3223(02)01742-0
Govindaraju, 2000, Proton NMR chemical shifts and coupling constants for brain metabolites, NMR Biomed, 13, 129, 10.1002/1099-1492(200005)13:3<129::AID-NBM619>3.0.CO;2-V
Bustillo, 2010, (1)H-MRS at 4 tesla in minimally treated early schizophrenia, Mol Psychiatry, 15, 629, 10.1038/mp.2009.121
Jessen, 2006, Proton magnetic resonance spectroscopy in subjects at risk for schizophrenia, Schizophr Res, 87, 81, 10.1016/j.schres.2006.06.011
Steen, 2005, Measurement of brain metabolites by 1H magnetic resonance spectroscopy in patients with schizophrenia: a systematic review and meta-analysis, Neuropsychopharmacology, 30, 1949, 10.1038/sj.npp.1300850
Pan, 2005, Interdependence of N-acetyl aspartate and high-energy phosphates in healthy human brain, Ann Neurol, 57, 92, 10.1002/ana.20317
Moffett, 2007, N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology, Prog Neurobiol, 81, 89, 10.1016/j.pneurobio.2006.12.003
Pouwels, 1997, Differential distribution of NAA and NAAG in human brain as determined by quantitative localized proton MRS, NMR Biomed, 10, 73, 10.1002/(SICI)1099-1492(199704)10:2<73::AID-NBM448>3.0.CO;2-4
Edden, 2007, In vivo differentiation of N-acetyl aspartyl glutamate from N-acetyl aspartate at 3 Tesla, Magn Reson Med, 57, 977, 10.1002/mrm.21234
Kay, 1987, The positive and negative syndrome scale (PANSS) for schizophrenia, Schizophr Bull, 13, 261, 10.1093/schbul/13.2.261
Helmstaedter, 2001, Verbaler Lern- und Merkfähigkeitstest (VLMT)
Tewes, 1991, Hamburg-Wechsler-Intelligenztest für Erwachsene, Revision 1991 (HAWIE-R)
Härting, 2000, Die Wechsler Memory Scale-Revised (WMS-R). Deutsche Version
Gold, 1997, Auditory working memory and Wisconsin Card Sorting Test performance in schizophrenia, Arch Gen Psychiatry, 54, 159, 10.1001/archpsyc.1997.01830140071013
Reitan, 1979, Trail Making Test (TMT)
Naressi, 2001, Java-based graphical user interface for the MRUI quantitation package, MAGMA, 12, 141, 10.1007/BF02668096
Ratiney, 2005, Time-domain semi-parametric estimation based on a metabolite basis set, NMR Biomed, 18, 1, 10.1002/nbm.895
Träber, 2004, 1H metabolite relaxation times at 3.0 tesla: measurements of T1 and T2 values in normal brain and determination of regional differences in transverse relaxation, J Magn Reson Imaging, 19, 537, 10.1002/jmri.20053
Vanhamme, 1997, Improved method for accurate and efficient quantification of MRS data with use of prior knowledge, J Magn Reson, 129, 35, 10.1006/jmre.1997.1244
Ghose, 2009, Differential expression of metabotropic glutamate receptors 2 and 3 in schizophrenia: a mechanism for antipsychotic drug action?, Am J Psychiatry, 166, 812, 10.1176/appi.ajp.2009.08091445
Guilarte, 2008, Dysregulation of glutamate carboxypeptidase II in psychiatric disease, Schizophr Res, 99, 324, 10.1016/j.schres.2007.11.013
Tsai, 2005, Central N-acetyl aspartylglutamate deficit: a possible pathogenesis of schizophrenia, Med Sci Monit, 11, HY39
Arun, 2008, Antipsychotic drugs increase N-acetylaspartate and N-acetylaspartylglutamate in SH-SY5Y human neuroblastoma cells, J Neurochem, 106, 1669, 10.1111/j.1471-4159.2008.05524.x
Fricker, 2009, Effects of N-acetylaspartylglutamate (NAAG) at group II mGluRs and NMDAR, Neuropharmacology, 56, 1060, 10.1016/j.neuropharm.2009.03.002
Wang, 2005, Selective impairment of attentional networks of orienting and executive control in schizophrenia, Schizophr Res, 78, 235, 10.1016/j.schres.2005.01.019
Camchong, 2008, Common neural circuitry supporting volitional saccades and its disruption in schizophrenia patients and relatives, Biol Psychiatry, 64, 1042, 10.1016/j.biopsych.2008.06.015
Tayoshi, 2009, Metabolite changes and gender differences in schizophrenia using 3-Tesla proton magnetic resonance spectroscopy (1H-MRS), Schizophr Res, 108, 69, 10.1016/j.schres.2008.11.014
Lutkenhoff, 2010, Proton MRS in twin pairs discordant for schizophrenia, Mol Psychiatry, 15, 308, 10.1038/mp.2008.87
Théberge, 2003, Glutamate and glutamine in the anterior cingulate and thalamus of medicated patients with chronic schizophrenia and healthy comparison subjects measured with 4.0-T proton MRS, Am J Psychiatry, 160, 2231, 10.1176/appi.ajp.160.12.2231
Olbrich, 2008, Frontolimbic glutamate alterations in first episode schizophrenia: evidence from a magnetic resonance spectroscopy study, World J Biol Psychiatry, 9, 59, 10.1080/15622970701227811