Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement

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Messroghli, 2003, T1 mapping in patients with acute myocardial infarction, J. Cardiovasc. Magn. Reson, 5, 353, 10.1081/JCMR-120019418

Messroghli, 2004, Modified look-locker inversion recovery (MOLLI) for high-resolution T1 mapping of the heart, Magn. Reson. Med, 52, 141, 10.1002/mrm.20110

Brading, 1969, Distribution and kinetics of CoEDTA in smooth muscle, and its use as an extracellular marker, J. Physiol, 200, 387, 10.1113/jphysiol.1969.sp008700

Poole-Wilson, 1975

Arheden, 1999, Measurement of the distribution volume of gadopentetate dimeglumine at echo-planar MR imaging to quantify myocardial infarction: comparison with 99mTc-DTPA autoradiography in rats, Radiology, 211, 698, 10.1148/radiology.211.3.r99jn41698

Jerosch-Herold, 2008, Cardiac magnetic resonance imaging of myocardial contrast uptake and blood flow in patients affected with idiopathic or familial dilated cardiomyopathy, Am. J. Physiol. Heart Circ. Physiol, 295, H1234, 10.1152/ajpheart.00429.2008

Ugander, 2012, Myocardial edema as detected by pre-contrast T1 and T2 CMR delineates area at risk associated with acute myocardial infarction, JACC Cardiovasc. Imaging, 5, 596, 10.1016/j.jcmg.2012.01.016

Ferreira, 2012, Non-contrast T1-mapping detects acute myocardial edema with high diagnostic accuracy: a comparison to T2-weighted cardiovascular magnetic resonance, J. Cardiovasc. Magn. Reson, 14, 42, 10.1186/1532-429X-14-42

Karamitsos, 2013, Noncontrast T1 mapping for the diagnosis of cardiac amyloidosis, JACC Cardiovasc. Imaging, 6, 488, 10.1016/j.jcmg.2012.11.013

Bull, 2013, Human non-contrast T1 values and correlation with histology in diffuse fibrosis, Heart, 99, 932, 10.1136/heartjnl-2012-303052

Sado, 2013, Identification and assessment of anderson-fabry disease by cardiovascular magnetic resonance noncontrast myocardial t1 mapping, Circ. Cardiovasc. Imaging, 6, 392, 10.1161/CIRCIMAGING.112.000070

Scholz, 1990, Effect of tissue fat and water content on nuclear magnetic resonance relaxation times of cardiac and skeletal muscle, Magn. Reson. Imaging, 8, 605, 10.1016/0730-725X(90)90138-R

Pedersen, 2012, Assessment of intramyocardial hemorrhage by T1-weighted cardiovascular magnetic resonance in reperfused acute myocardial infarction, J. Cardiovasc. Magn. Reson, 14, 59, 10.1186/1532-429X-14-59

Puntmann, 2013, Native myocardial T1 mapping by cardiovascular magnetic resonance imaging in subclinical cardiomyopathy in patients with systemic lupus erythematosus, Circ. Cardiovasc. Imaging, 6, 295, 10.1161/CIRCIMAGING.112.000151

Sado, 2013, The identification and assessment of Anderson Fabry disease by cardiovascular magnetic resonance non-contrast myocardial T1 mapping, Circ. Cardiovasc. Imaging, 6, 392, 10.1161/CIRCIMAGING.112.000070

Dall'Armellina, 2012, Cardiovascular magnetic resonance by non contrast T1-mapping allows assessment of severity of injury in acute myocardial infarction, J. Cardiovasc. Magn. Reson, 14, 15, 10.1186/1532-429X-14-15

Ferreira, 2013, T mapping for the diagnosis of acute myocarditis using CMR: comparison to T-weighted and late gadolinium enhanced imaging, JACC Cardiovasc Imaging, 10.1016/j.jcmg.2013.03.008

Weber, 1991, Pathological hypertrophy and cardiac interstitium: fibrosis and renin-angiotensin-aldosterone system, Circulation, 83, 1849, 10.1161/01.CIR.83.6.1849

Wong, 2012, Association between extracellular matrix expansion quantified by cardiovascular magnetic resonance and short-term mortality, Circulation, 126, 1206, 10.1161/CIRCULATIONAHA.111.089409

Wong, 2013, Myocardial extracellular volume fraction quantified by cardiovascular magnetic resonance is increased in diabetes and associated with mortality and incident heart failure admission, Eur. Heart J

Butler, 2013, Strategies and opportunities for drug development in heart failure, JAMA, 309, 1593, 10.1001/jama.2013.1063

Banypersad, 2012, Quantification of myocardial extracellular volume fraction in systemic AL amyloidosis: an equilibrium contrast cardiovascular magnetic resonance study, Circ. Cardiovasc. Imaging, 6, 34, 10.1161/CIRCIMAGING.112.978627

Fontana, 2012, Comparison of T1 mapping techniques for ECV quantification: histological validation and reproducibility of ShMOLLI versus multibreath-hold T1 quantification equilibrium contrast CMR, J. Cardiovasc. Magn. Reson, 14, 88, 10.1186/1532-429X-14-88

Brilla, 2000, Lisinopril-mediated regression of myocardial fibrosis in patients with hypertensive heart disease, Circulation, 102, 1388, 10.1161/01.CIR.102.12.1388

Diez, 2002, Losartan-dependent regression of myocardial fibrosis is associated with reduction of left ventricular chamber stiffness in hypertensive patients, Circulation, 105, 2512, 10.1161/01.CIR.0000017264.66561.3D

Izawa, 2005, Mineralocorticoid receptor antagonism ameliorates left ventricular diastolic dysfunction and myocardial fibrosis in mildly symptomatic patients with idiopathic dilated cardiomyopathy: a pilot study, Circulation, 112, 2940, 10.1161/CIRCULATIONAHA.105.571653

McLenachan, 1990, Ventricular arrhythmias in hypertensive left ventricular hypertrophy: relationship to coronary artery disease, left ventricular dysfunction, and myocardial fibrosis, Am. J. Hypertens, 3, 735, 10.1093/ajh/3.10.735

Kawara, 2001, Activation delay after premature stimulation in chronically diseased human myocardium relates to the architecture of interstitial fibrosis, Circulation, 104, 3069, 10.1161/hc5001.100833

Anderson, 1993, Myocardial electrical propagation in patients with idiopathic dilated cardiomyopathy, J. Clin. Invest, 92, 122, 10.1172/JCI116540

Tamarappoo, 2012, Vulnerable myocardial interstitium in patients with isolated left ventricular hypertrophy and sudden cardiac death: a postmortem histological evaluation, J Am Heart Assoc, 1, e001511, 10.1161/JAHA.112.001511

Schwartzkopff, 2000, Repair of coronary arterioles after treatment with perindopril in hypertensive heart disease, Hypertension, 36, 220, 10.1161/01.HYP.36.2.220

Naghavi, 2003, From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I, Circulation, 108, 1664, 10.1161/01.CIR.0000087480.94275.97

Khavandi, 2009, Diabetic cardiomyopathy–a distinct disease?, Best Pract. Res. Clin. Endocrinol. Metab, 23, 347, 10.1016/j.beem.2008.10.016

Asbun, 2006, The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy, J. Am. Coll. Cardiol, 47, 693, 10.1016/j.jacc.2005.09.050

Goser, 2006, Cardiac troponin I but not cardiac troponin T induces severe autoimmune inflammation in the myocardium, Circulation, 114, 1693, 10.1161/CIRCULATIONAHA.106.635664

Van Hoeven, 1990, A comparison of the pathological spectrum of hypertensive, diabetic, and hypertensive-diabetic heart disease, Circulation, 82, 848, 10.1161/01.CIR.82.3.848

Wynn, 2012, Mechanisms of fibrosis: therapeutic translation for fibrotic disease, Nat. Med, 18, 1028, 10.1038/nm.2807

Beltrami, 1994, Structural basis of end-stage failure in ischemic cardiomyopathy in humans, Circulation, 89, 151, 10.1161/01.CIR.89.1.151

Beltrami, 1995, The cellular basis of dilated cardiomyopathy in humans, J. Mol. Cell. Cardiol, 27, 291, 10.1016/S0022-2828(08)80028-4

Schelbert, 2012, Prevalence and prognosis of unrecognized myocardial infarction determined by cardiac magnetic resonance in older adults, JAMA, 308, 890, 10.1001/2012.jama.11089

Wong, 2013, Effectiveness of late gadolinium enhancement to improve outcomes prediction in patients referred for cardiovascular magnetic resonance after echocardiography, J. Cardiovasc. Magn. Reson, 15, 1, 10.1186/1532-429X-15-6

Cheong, 2009, Prognostic significance of delayed-enhancement magnetic resonance imaging: survival of 857 patients with and without left ventricular dysfunction, Circulation, 120, 2069, 10.1161/CIRCULATIONAHA.109.852517

Klem, 2011, Prognostic value of routine cardiac magnetic resonance assessment of left ventricular ejection fraction and myocardial damage: an international multicenter study, Circ. Cardiovasc. Imaging, 4, 610, 10.1161/CIRCIMAGING.111.964965

Kim, 2000, The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction, N. Engl. J. Med, 343, 1445, 10.1056/NEJM200011163432003

Gulati, 2013, Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy, JAMA, 309, 896, 10.1001/jama.2013.1363

De Waha, 2010, Impact of early vs. late microvascular obstruction assessed by magnetic resonance imaging on long-term outcome after ST-elevation myocardial infarction: a comparison with traditional prognostic markers, Eur. Heart J, 31, 2660, 10.1093/eurheartj/ehq247

Sado, 2012, Cardiovascular magnetic resonance measurement of myocardial extracellular volume in health and disease, Heart, 98, 1436, 10.1136/heartjnl-2012-302346

Kellman, 2012, Extracellular volume fraction mapping in the myocardium, Part 2: initial clinical experience, J. Cardiovasc. Magn. Reson, 14, 64

Broberg, 2010, Quantification of diffuse myocardial fibrosis and its association with myocardial dysfunction in congenital heart disease, Circ. Cardiovasc. Imaging, 3, 727, 10.1161/CIRCIMAGING.108.842096

Ugander, 2012, Extracellular volume imaging by magnetic resonance imaging provides insights into overt and sub-clinical myocardial pathology, Eur. Heart J, 33, 1268, 10.1093/eurheartj/ehr481

Flett, 2012, Diffuse myocardial fibrosis in severe aortic stenosis: an equilibrium contrast cardiovascular magnetic resonance study, Eur Heart J Cardiovasc Imaging, 13, 819, 10.1093/ehjci/jes102

Mongeon, 2012, Quantification of extracellular matrix expansion by CMR in infiltrative heart disease, JACC Cardiovasc. Imaging, 5, 897, 10.1016/j.jcmg.2012.04.006

Flett, 2010, Equilibrium contrast cardiovascular magnetic resonance for the measurement of diffuse myocardial fibrosis: preliminary validation in humans, Circulation, 122, 138, 10.1161/CIRCULATIONAHA.109.930636

Schalla, 2010, Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy, Eur. J. Heart Fail, 12, 227, 10.1093/eurjhf/hfq004

Schelbert, 2011, Myocardial extravascular extracellular volume fraction measurement by gadolinium cardiovascular magnetic resonance in humans: slow infusion versus bolus, J. Cardiovasc. Magn. Reson, 13, 16, 10.1186/1532-429X-13-16

Shah, 2013, Myocardial tissue remodeling in adolescent obesity, J Am Heart Assoc, 2, e000279, 10.1161/JAHA.113.000279

Tham, 2013, Diffuse myocardial fibrosis by T1-mapping in children with subclinical anthracycline cardiotoxicity: relationship to exercise capacity, cumulative dose and remodeling, J. Cardiovasc. Magn. Reson, 15, 48, 10.1186/1532-429X-15-48

Kellman, 2012, Extracellular volume fraction mapping in the myocardium, Part 1: evaluation of an automated method, J. Cardiovasc. Magn. Reson, 14, 63

Tyralla, 2011, High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy, PLoS One, 6, e15287, 10.1371/journal.pone.0015287

Roffe, 1998, Ageing of the heart, Br. J. Biomed. Sci, 55, 136

Urbieta-Caceres, 2011, Reversal of experimental renovascular hypertension restores coronary microvascular function and architecture, Am. J. Hypertens, 24, 458, 10.1038/ajh.2010.259

Miller, 2013, Comprehensive validation of cardiovascular magnetic resonance techniques for the assessment of myocardial extracellular volume, Circ Cardiovasc Imaging, 6, 373, 10.1161/CIRCIMAGING.112.000192

Anderson, 1979, Histopathological types of cardiac fibrosis in myocardial disease, J. Pathol, 128, 79, 10.1002/path.1711280205

Swynghedauw, 1999, Molecular mechanisms of myocardial remodeling, Physiol. Rev, 79, 215, 10.1152/physrev.1999.79.1.215

White, 2013, T1 mapping for myocardial extracellular volume measurement by CMR: bolus only versus primed infusion technique, JACC Cardiovasc. Imaging, 10.1016/j.jcmg.2013.01.011

Kellman, 2013, T1 and extracellular volume mapping in the heart: estimation of error maps and the influence of noise on precision, J. Cardiovasc. Magn. Reson, 15, 56, 10.1186/1532-429X-15-56

Bossuyt, 2003, Towards complete and accurate reporting of studies of diagnostic accuracy: the STARD initiative, BMJ, 326, 41, 10.1136/bmj.326.7379.41

Robson, 2013, T1 measurements in the human myocardium: the effects of magnetization transfer on the SASHA and MOLLI sequences, Magn Reson Med, 10.1002/mrm.24867

Iles, 2008, Evaluation of diffuse myocardial fibrosis in heart failure with cardiac magnetic resonance contrast-enhanced T1 mapping, J. Am. Coll. Cardiol, 52, 1574, 10.1016/j.jacc.2008.06.049

Sibley, 2012, T1 mapping in cardiomyopathy at cardiac MR: comparison with endomyocardial biopsy, Radiology, 265, 724, 10.1148/radiol.12112721

Kawel, 2012, T1 mapping of the myocardium: intra-individual assessment of post-contrast T1 time evolution and extracellular volume fraction at 3T for Gd-DTPA and Gd-BOPTA, J. Cardiovasc. Magn. Reson, 14, 26, 10.1186/1532-429X-14-26

Markl, 2004, On flow effects in balanced steady-state free precession imaging: pictorial description, parameter dependence, and clinical implications, J. Magn. Reson. Imaging, 20, 697, 10.1002/jmri.20163

Kellman, 2013, Influence of off-resonance in myocardial T1-mapping using SSFP based MOLLI method, J. Cardiovasc. Magn. Reson, 15, 63, 10.1186/1532-429X-15-63

Hunold, 2005, Myocardial late enhancement in contrast-enhanced cardiac MRI: distinction between infarction scar and non-infarction-related disease, AJR Am. J. Roentgenol, 184, 1420, 10.2214/ajr.184.5.01841420

Mahrholdt, 2005, Delayed enhancement cardiovascular magnetic resonance assessment of non-ischaemic cardiomyopathies, Eur. Heart J, 26, 1461, 10.1093/eurheartj/ehi258

Flett, 2011, Evaluation of techniques for the quantification of myocardial scar of differing etiology using cardiac magnetic resonance, JACC Cardiovasc. Imaging, 4, 150, 10.1016/j.jcmg.2010.11.015

Zhou, 2004, Simultaneous measurement of arterial input function and tumor pharmacokinetics in mice by dynamic contrast enhanced imaging: effects of transcytolemmal water exchange, Magn. Reson. Med, 52, 248, 10.1002/mrm.20143

Landis, 1999, Equilibrium transcytolemmal water-exchange kinetics in skeletal muscle in vivo, Magn. Reson. Med, 42, 467, 10.1002/(SICI)1522-2594(199909)42:3<467::AID-MRM9>3.0.CO;2-0

Coelho-Filho, 2013, The role of transcytolemmal water exchange in magnetic resonance measurements of diffuse myocardial fibrosis in hypertensive heart disease, Circ Cardiovasc Imaging, 134, 41

Messroghli, 2006, Human myocardium: single-breath-hold MR T1 mapping with high spatial resolution–reproducibility study, Radiology, 238, 1004, 10.1148/radiol.2382041903

Messroghli, 2007, Optimization and validation of a fully-integrated pulse sequence for modified look-locker inversion-recovery (MOLLI) T1 mapping of the heart, J. Magn. Reson. Imaging, 26, 1081, 10.1002/jmri.21119

Piechnik, 2010, Shortened modified look-locker inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold, J. Cardiovasc. Magn. Reson, 12, 69, 10.1186/1532-429X-12-69

Chow, 2013, Saturation recovery single-shot acquisition (SASHA) for myocardial T mapping, Magn Reson Med

Piechnik, 2013, Normal variation of magnetic resonance T1 relaxation times in the human population at 1.5 T using ShMOLLI, J. Cardiovasc. Magn. Reson, 15, 13, 10.1186/1532-429X-15-13

Coelho-Filho, 2013, Role of transcytolemmal water-exchange in magnetic resonance measurements of diffuse myocardial fibrosis in hypertensive heart disease, Circ. Cardiovasc. Imaging, 6, 134, 10.1161/CIRCIMAGING.112.979815

Sado, 2011, Novel imaging techniques for diffuse myocardial fibrosis, Future Cardiol, 7, 643, 10.2217/fca.11.45

Kwong, 2011, Measuring myocardial scar by CMR, JACC Cardiovasc. Imaging, 4, 157, 10.1016/j.jcmg.2010.12.004

Nacif, 2012, Interstitial myocardial fibrosis assessed as extracellular volume fraction with low-radiation-dose cardiac CT, Radiology, 264, 876, 10.1148/radiol.12112458