Mutations in signal transduction pathways and inherited diseases

Nishizuka, 1986, Studies and Perspectives of Protein Kinase C, Science, 233, 305, 10.1126/science.3014651 Berridge, 1987, Inositol Triphosphate and Diacylglycerol: Two Interacting Second Messengers, Ann Rev Biochem, 56, 159, 10.1146/annurev.bi.56.070187.001111 Borrelli, 1992, Signal Transduction and Gene Control: The cAMP Pathway, CRC Rev Oncogenesis Hunter, 1987, A Thousand and One Protein Kinases, Cell, 50, 823, 10.1016/0092-8674(87)90509-5 Montmayeur, 1991, Transcription Mediated by a cAMP-responsive Promoter Element is Reduced Upon Activation of Dopamine D2 Receptors, 88, 3135 Cantley, 1991, Oncogenes and Signal Transduction, Cell, 64, 281, 10.1016/0092-8674(91)90639-G Angel, 1991, The Role of Jun, Fos and the AP-1 Complex in Cell-proliferation and Transformation, Biochem Biophys Acta, 1072, 129 Sen, 1986, Inducibility of χ Immunoglobulin Enhancer Protein NF-χB by a Post-translational Mechanism, Cell, 47, 921, 10.1016/0092-8674(86)90807-X Foulkes, 1991, CREM Gene: Use of Alternative DNA-binding Domains Generates Multiple Antagonists of cAMP-induced Transcription, Cell, 64, 739, 10.1016/0092-8674(91)90503-Q Prywes, 1988, Phosphorylation of Serum Response Factor, a Factor that Binds to the Serum Response Element in the c-fos Promoter, 85, 7206 Kieran, 1990, The DNA-binding Subunit of NF-ϰB is Identical to Factor KBF1 and Homologous to the rel Oncogene Product, Cell, 62, 1007, 10.1016/0092-8674(90)90275-J Lewin, 1991, Oncogenic Conversion by Regulatory Changes in Transcription Factors, Cell, 64, 303, 10.1016/0092-8674(91)90640-K Hunter, 1991, Cooperation Between Oncogenes, Cell, 64, 249, 10.1016/0092-8674(91)90637-E Auwerx, 1991, IP-1: A Dominant Inhibitor of Fos-Jun Whose Activity is Modulated by Phosphorylation, Cell, 64, 983, 10.1016/0092-8674(91)90322-P Baichwal, 1990, Control of cJun Activity by Interaction of a Cell-specific Inhibitor with Regulatory Domain δ: Differences Between v- and c-Jun, Cell, 63, 815, 10.1016/0092-8674(90)90147-7 Madden, 1991, Transcriptional Repression Mediated by the WT1 Wilms Tumour Gene Product, Science, 253, 1550, 10.1126/science.1654597 Beckwith, 1986, Wilms' Tumour and Other Renal Tumours of Childhood: An Update, J Urol, 136, 320, 10.1016/S0022-5347(17)44854-3 Landis, 1989, GTPase Inhibiting Mutations Activate the α chain of Gs and Stimulate Adenylyl Cyclase in Human Pituitary Tumours, Nature, 340, 692, 10.1038/340692a0 Lyons, 1990, Two G Protein Oncogenes in Human Endocrine Tumours, Science, 249, 655, 10.1126/science.2116665 Wong, 1991, Mutant α Subunits of Gi2 Inhibit Cyclic AMP Accumulation, Nature, 351, 63, 10.1038/351063a0 Weinstein, 1991, Activating Mutations of the Stimulatory G Protein in the McCune-Albright Syndrome, New Engl J Med, 325, 1688, 10.1056/NEJM199112123252403 Levine, 1991, The McCune-Albright Syndrome. The Whys and Wherefores of Abnormal Signal Transduction, New Engl J Med, 325, 1738, 10.1056/NEJM199112123252410 Molloy, 1989, PDGF Induction of Tyrosine Phosphorylation of GTPase Activating Protein, Nature, 342, 711, 10.1038/342711a0 Ellis, 1990, Phosphorylation of GAP and GAP-associated Proteins by Transforming and Mitogenic Tyrosine Kinases, Nature, 343, 377, 10.1038/343377a0 Xu, 1990, The Catalytic Domain of the Neurofibromatosis Type 1 Gene Product Stimulates ras GT-Pase and Complements ira Mutants of S. cerevisiae, Cell, 63, 835, 10.1016/0092-8674(90)90149-9 Martin, 1990, The GAP-related Domain of the Neurofibromatosis Type 1 Gene Product Interacts with ras p21, Cell, 63, 843, 10.1016/0092-8674(90)90150-D Ballester, 1990, The NF1 Locus Encodes a Protein Functionally Related to Mammalian GAP and Yeast IRA Proteins, Cell, 63, 851, 10.1016/0092-8674(90)90151-4 Bollag, 1991, Differential Regulation of ras-GAP and Neurofibromatosis Gene Product Activities, Nature, 351, 576, 10.1038/351576a0 Julius, 1989, Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation, Science, 244, 1057, 10.1126/science.2727693 Rommens, 1989, Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping, Science, 245, 1059, 10.1126/science.2772657 Riordan, 1989, Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA, Science, 245, 1066, 10.1126/science.2475911 Kerem, 1989, Identification of the Cystic Fibrosis Gene: Genetic Analysis, Science, 245, 1073, 10.1126/science.2570460 Wagner, 1991, Activation of Chloride Channels in Normal and Cystic Fibrosis Airway Epithelial Cells by Multifunctional Calcium/Calmodulin-dependent Protein Kinase, Nature, 349, 793, 10.1038/349793a0