Mutational Analysis of the CTNNB1 and APC Genes in Uterine Endometrioid Carcinoma

Modern Pathology - Tập 13 - Trang 1066-1071 - 2000
Peter W Schlosshauer1, Edyta C Pirog1, Ross L Levine1, Lora Hedrick Ellenson1
1Department of Pathology, Joan and Sanford I. Weill Medical College of Cornell University, New York

Tài liệu tham khảo

Bristow, 1999, Endometrial cancer, Curr Opin Oncol, 11, 388, 10.1097/00001622-199909000-00012 Hedrick, 1998, Endometrial cancer, 621 Kinzler, 1998, Colorectal tumors, 565 Sparks, 1998, Mutational analysis of the APC/β-catenin/Tcf pathway in colorectal cancer, Cancer Res, 58, 1130 Young, 1998, Wnt-1 induces growth, cytosolic β-catenin, and Tcf/Lef transcriptional activation in rat-1 fibroblasts, Mol Cell Biol, 18, 2474, 10.1128/MCB.18.5.2474 Shimizu, 1997, Transformation by Wnt family proteins correlates with regulation of β-catenin, Cell Growth Differ, 8, 1349 Korinek, 1997, Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC−/− colon carcinoma, Science, 275, 1784, 10.1126/science.275.5307.1784 He, 1998, Identification of c-MYC as a target of the APC pathway, Science, 281, 1509, 10.1126/science.281.5382.1509 Tetsu, 1999, β-catenin regulates expression of cyclin D1 in colon carcinoma cells, Nature, 398, 422, 10.1038/18884 Ilyas, 1997, The interactions of APC, E-cadherin and β-catenin in tumour development and progression, J Pathol, 182, 128, 10.1002/(SICI)1096-9896(199706)182:2<128::AID-PATH839>3.0.CO;2-Q Polakis, 1999, The oncogenic activation of β-catenin [review], Curr Opin Genet Dev, 9, 15, 10.1016/S0959-437X(99)80003-3 Pennisi, 1998, How a growth control path takes a wrong turn to cancer, Science, 281, 1438, 10.1126/science.281.5382.1438 Miyoshi, 1992, Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene, Hum Mol Genet, 1, 229, 10.1093/hmg/1.4.229 Fukuchi, 1998, β-catenin mutation in carcinoma of the uterine endometrium, Cancer Res, 58, 3526 Kobayashi, 1999, Mutations of the β-catenin gene in endometrial carcinomas, Jpn J Cancer Res, 90, 55, 10.1111/j.1349-7006.1999.tb00665.x Palacios, 1998, Mutations in the β-catenin gene (CTNNB1) in endometrioid ovarian carcinomas, Cancer Res, 58, 1344 Fearon, 1987, Clonal analysis of human colorectal tumors, Science, 238, 193, 10.1126/science.2889267 Katabuchi, 1995, Mutations in DNA mismatch repair genes are not responsible for microsatellite instability in most sporadic endometrial carcinomas, Cancer Res, 55, 5556 Van der Luijt, 1994, Rapid detection of translation-terminating mutations at the adenomatous polyposis coli (APC) gene by direct protein truncation test, Genomics, 20, 1, 10.1006/geno.1994.1119 Tashiro, 1997, Mutations in PTEN are frequent in endometrial carcinoma, but rare in other common gynecological malignancies, Cancer Res, 57, 3935 Burks, 1994, Microsatellite instability in endometrial carcinoma, Oncogene, 9, 1163 Esteller, 1998, hMLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinoma, Oncogene, 16, 2413, 10.1038/sj.onc.1202178 Ilyas, 1997, β-catenin mutations in cell lines established from human colorectal cancers, Proc Nat Acad Sci U S A, 94, 10330, 10.1073/pnas.94.19.10330 Rubinfeld, 1997, Stabilization of β-catenin by genetic defects in melanoma cell lines, Science, 275, 1790, 10.1126/science.275.5307.1790 Zurawel, 1998, Sporadic medulloblastomas contain oncogenic β-catenin mutations, Cancer Res, 58, 896 Voeller, 1998, β-catenin mutations in human prostate cancer, Cancer Res, 58, 2520 Kawanishi, 1995, Loss of E-cadherin-dependent cell-cell adhesion due to mutation of the β-catenin gene in a human cancer cell line, HSC-39, Mol Cell Biol, 15, 1175, 10.1128/MCB.15.3.1175 Miyoshi Y, Iwao K, Nagasawa Y, Aihara T, Sasaki Y, Imaoka S, et al. Activation of the β-catenin gene in primary hepatocellular carcinomas by somatic alterations involving exon 3. Cancer Res; 58: 2524–2527. De La Coste, 1998, Somatic mutations of the β-catenin gene are frequent in mouse and human hepatocellular carcinomas, Proc Natl Acad Sci U S A, 95, 8847, 10.1073/pnas.95.15.8847 Sato, 1991, Expression of c-myc, epidermal growth factor receptor and c-erbB-2 in human endometrial carcinoma and cervical adenocarcinoma, Tohoku J Exp Med, 165, 137, 10.1620/tjem.165.137 Bai, 1994, Immunohistochemical detection of the c-myc oncogene product in normal, hyperplastic and carcinomatous endometrium, Oncology, 51, 314, 10.1159/000227356 Yokoyama, 1998, Value of glutathione S-transferase pi and the oncogene products c-Jun, c-Fos, c-H-Ras, and c-Myc as a prognostic indicator in endometrial carcinomas, Gynecol Oncol, 68, 280, 10.1006/gyno.1998.4936 Nikaido, 1996, Coabnormal expression of cyclin D1 and p53 protein in human uterine endometrial carcinomas, Cancer, 78, 1248, 10.1002/(SICI)1097-0142(19960915)78:6<1248::AID-CNCR12>3.0.CO;2-0 Ito, 1998, Immunohistochemical study of cyclins D and E and cyclin dependent kinase (cdk) 2 and 4 in human endometrial carcinoma, Anticancer Res, 18, 1661 Prall, 1997, Estrogen-induced activation of Cdk4 and Cdk2 during G1-S phase progression is accompanied by increased cyclin D1 expression and decreased cyclin-dependent kinase inhibitor association with cyclin E-Cdk2, J Biol Chem, 272, 10882, 10.1074/jbc.272.16.10882 Altucci, 1996, 17 beta-Estradiol induces cyclin D1 gene transcription, p36D1–p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells, Oncogene, 12, 2315 Prall, 1998, c-Myc or cyclin D1 mimics estrogen effects on cyclin E-Cdk2 activation and cell cycle reentry, Mol Cell Biol, 18, 4499, 10.1128/MCB.18.8.4499