Multipolar radiofrequency ablation with non‐touch technique for hepatocellular carcinoma ≤ 3 cm: A preliminary report

ADVANCES IN DIGESTIVE MEDICINE - Tập 1 - Trang 80-85 - 2014
Li-Wei Wu1, Chiung-Yu Chen2, Chun-Jen Liu3, Ming-Yao Chen1, Po-Chun Liu1, Pan-Fu Liu1, Olivier Seror4, I-Lin Lee1, Shi-Ming Lin5
1Department of Internal Medicine, Taipei Medical University Shuang-Ho Hospital, Taipei, Taiwan
2Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan
3Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
4Department of Radiology, APHP Jean-Verdier Hospital, Paris, France
5Division of Hepatology, Department of Gastroenterology and Hepatology, Chang-Gung Memorial Hospital, Taipei, Taiwan

Tóm tắt

SummaryBackgroundConventional monopolar radiofrequency ablation (RFA) bears the risks of incomplete ablation and tumor seeding. This study aimed to evaluate the effectiveness and safety of multipolar RFA with non‐touch technique for hepatocellular carcinoma (HCC) ≤ 3 cm.MethodsFifteen cirrhotic patients (9 men, 6 women; age 51–83 years, mean 64.4 years, Child‐Pugh score: A = 10 and B = 5) with 17 HCCs of ≤ 3 cm (mean: 26 mm), which were diagnosed based on typical radiologic findings were enrolled. Two or three Celon Prosurge Bipolar electrodes with 3‐cm active tip were deployed with non‐touch technique via percutaneous approach under ultrasound guidance.ResultsComplete ablation was achieved in all 17 lesions. This is defined as no enhanced part around the ablated index tumors according to dynamic computed tomography or magnetic resonance imaging at least 1 month after ablation. No local tumor progression was detected at follow‐up (range, 3–21.5 months; mean, 10 months). No track seeding was observed. There was one distant recurrence 15.4 months after ablation. One patient had procedure‐related biliary stricture and died of pneumonia 3.5 months after tumor ablation.ConclusionMultipolar RFA with non‐touch technique is an effective method to achieve complete tumor ablation and an adequate safety margin. This method has low complication rate and bears minimal risk of tumor seeding.

Tài liệu tham khảo

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