Multiplexed DNA detection with DNA tweezers in a one-pot reaction

Dobnik, 2014, Simultaneous detection of RNA and DNA targets based on multiplex isothermal amplification, J. Agric. Food Chem., 62, 2989, 10.1021/jf5002149 Vijian, 2016, Non-protein coding RNA-based genosensor with quantum dots as electrochemical labels for attomolar detection of multiple pathogens, Biosens. Bioelectron., 77, 805, 10.1016/j.bios.2015.10.057 Wang, 2017, Simultaneous imaging of three tumor-related mRNAs in living cells with a DNA tetrahedron-based multicolor nanoprobe, ACS Sensors, 2, 735, 10.1021/acssensors.7b00290 Zeng, 2017, DNA tetrahedral nanostructure-based electrochemical miRNA biosensor for simultaneous detection of multiple miRNAs in pancreatic carcinoma, ACS Appl. Mater. Interfaces, 9, 24118, 10.1021/acsami.7b05981 Zhang, 2010, Aptamer-based multicolor fluorescent gold nanoprobes for multiplex detection in homogeneous solution, Small, 6, 201, 10.1002/smll.200901012 Douglas, 2009, Self-assembly of DNA into nanoscale three-dimensional shapes, Nature, 459, 414, 10.1038/nature08016 Rothemund, 2006, Folding DNA to create nanoscale shapes and patterns, Nature, 440, 297, 10.1038/nature04586 Ouyang, 2017, Docking of antibodies into the cavities of DNA origami structures, Angew. Chem. Int. Ed., 56, 14423, 10.1002/anie.201706765 Ding, 2010, Gold nanoparticle self-similar chain structure organized by DNA origami, J. Am. Chem. Soc., 132, 3248, 10.1021/ja9101198 Sun, 2014, Casting inorganic structures with DNA molds, Science, 346, 10.1126/science.1258361 Knudsen, 2015, Routing of individual polymers in designed patterns, Nat. Nanotechnol., 10, 892, 10.1038/nnano.2015.190 Krissanaprasit, 2016, Programmed switching of single polymer conformation on DNA origami, ACS Nano, 10, 2243, 10.1021/acsnano.5b06894 Madsen, 2017, Preparation, single-molecule manipulation, and energy transfer investigation of a polyfluorene-graft-DNA polymer, Chem. Eur. J., 23, 10511, 10.1002/chem.201702780 Jiang, 2012, DNA origami as a carrier for circumvention of drug resistance, J. Am. Chem. Soc., 134, 13396, 10.1021/ja304263n Lee, 2012, Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery, Nat. Nanotechnol., 7, 389, 10.1038/nnano.2012.73 Zhao, 2012, DNA origami delivery system for cancer therapy with tunable release properties, ACS Nano, 6, 8684, 10.1021/nn3022662 Kuzyk, 2012, DNA-based self-assembly of chiral plasmonic nanostructures with tailored optical response, Nature, 483, 311, 10.1038/nature10889 Pal, 2011, DNA directed self-assembly of anisotropic plasmonic nanostructures, J. Am. Chem. Soc., 133, 17606, 10.1021/ja207898r Wen, 2012, DNA Nanostructure-based Interfacial engineering for PCR-free ultrasensitive electrochemical analysis of microRNA, Sci. Rep., 2, 867, 10.1038/srep00867 Lin, 2014, Programmable engineering of a biosensing interface with tetrahedral DNA nanostructures for ultrasensitive DNA detection, Angew. Chem. Int. Ed., 54, 2151, 10.1002/anie.201410720 Krissanaprasit, 2011, RGB colour coding of Y-shaped DNA for simultaneous tri-analyte solid phase hybridization detection, Biosens. Bioelectron., 26, 2183, 10.1016/j.bios.2010.09.028 Li, 2005, Multiplexed detection of pathogen DNA with DNA-based fluorescence nanobarcodes, Nat. Biotechnol., 23, 885, 10.1038/nbt1106 Lin, 2012, Submicrometre geometrically encoded fluorescent barcodes self-assembled from DNA, Nat Chem., 4, 832, 10.1038/nchem.1451 Liu, 2013, A DNA tweezer-actuated enzyme nanoreactor, Nat. Commun., 4 Müller, 2006, Single-pair FRET characterization of DNA tweezers, Nano Lett., 6, 2814, 10.1021/nl0619406 Yurke, 2000, A DNA-fuelled molecular machine made of DNA, Nature, 406, 605, 10.1038/35020524 Zhou, 2012, Reversible regulation of protein binding affinity by a DNA machine, J. Am. Chem. Soc., 134, 1416, 10.1021/ja209590u Gong, 2015, RNA-regulated molecular tweezers for sensitive fluorescent detection of microRNA from cancer cells, Biosens. Bioelectron., 71, 98, 10.1016/j.bios.2015.04.003 Douglas, 2009, Rapid prototyping of 3D DNA-origami shapes with caDNAno, Nucl. Acids Res., 37, 5001, 10.1093/nar/gkp436 Zhang, 2011, Dynamic DNA nanotechnology using strand-displacement reactions, Nat. Chem., 3, 103, 10.1038/nchem.957 Goodman, 2005, Rapid chiral assembly of rigid DNA building blocks for molecular nanofabrication, Science, 310, 1661, 10.1126/science.1120367 Goodman, 2008, Reconfigurable, braced, three-dimensional DNA nanostructures, Nat. Nanotechnol., 3, 93, 10.1038/nnano.2008.3 Mao, 2016, Activity modulation and allosteric control of a scaffolded DNAzyme using a dynamic DNA nanostructure, Chem. Sci., 7, 1200, 10.1039/C5SC03705K Xie, 2017, DNA tetrahedron nanostructures for biological applications: biosensors and drug delivery, Analyst, 142, 3322, 10.1039/C7AN01154G Song, 2016, Dynamic modulation of DNA hybridization using allosteric DNA tetrahedral nanostructures, Anal. Chem., 88, 8043, 10.1021/acs.analchem.6b01373 Pei, 2012, Reconfigurable three-dimensional DNA nanostructures for the construction of intracellular logic sensors, Angew. Chem. Int. Ed., 51, 9020, 10.1002/anie.201202356 Ge, 2014, Hybridization chain reaction amplification of microRNA detection with a tetrahedral DNA nanostructure-based electrochemical biosensor, Anal Chem., 86, 2124, 10.1021/ac4037262 Borse, 2019, Process parameter optimization for lateral flow immunosensing, Mater. Sci. Energy Technol., 2, 434 Fu, 2012, Interenzyme substrate diffusion for an enzyme cascade organized on spatially addressable DNA nanostructures, J. Am. Chem. Soc., 134, 5516, 10.1021/ja300897h Fu, 2013, Single-step rapid assembly of DNA origami nanostructures for addressable nanoscale bioreactors, J. Am. Chem. Soc., 135, 696, 10.1021/ja3076692 Linko, 2015, A modular DNA origami-based enzyme cascade nanoreactor, Chem. Commun, 51, 5351, 10.1039/C4CC08472A Kumar, 2018, Nanoengineered material based biosensing electrodes for enzymatic biofuel cells applications, Mater. Sci. Energy Technol., 1, 38