Multilayered biomimetic scaffolds for cartilage repair of the talus. A systematic review of the literature

O'Loughlin, 2010, Current concepts in the diagnosis and treatment of osteochondral lesions of the ankle, Am J Sports Med, 38, 392, 10.1177/0363546509336336 Looze, 2017, Evaluation and management of osteochondral lesions of the talus, Cartilage, 8, 19, 10.1177/1947603516670708 van Dijk, 2010, Osteochondral defects in the ankle: why painful, Knee Surg Sports Trauma Arthrosc, 18, 570, 10.1007/s00167-010-1064-x Kolar, 2021, Patient-reported joint status and quality of life in sports-related ankle disorders and osteoarthritis, Int Orthop, 45, 1049, 10.1007/s00264-020-04747-y Hannon, 2014, Osteochondral lesions of the talus: aspects of current management, Bone Jt J, 96, 164, 10.1302/0301-620X.96B2.31637 Zengerink, 2006, Current concepts: treatment of osteochondral ankle defects, Foot Ankle Clin, 11, 331, 10.1016/j.fcl.2006.03.008 Steele, 2018, Osteochondral lesions of the talus: current concepts in diagnosis and treatment, Foot Ankle Orthop, 3, 10.1177/2473011418779559 Zengerink, 2010, Treatment of osteochondral lesions of the talus: a systematic review, Knee Surg Sports Trauma Arthrosc, 18, 238, 10.1007/s00167-009-0942-6 Marcacci, 2013, Treatment of cartilage lesions: what works and why, Injury, 44, S11, 10.1016/S0020-1383(13)70004-4 Murawski, 2013, Operative treatment of osteochondral lesions of the talus, J Bone Jt Surg Am, 95, 1045, 10.2106/JBJS.L.00773 Vuurberg, 2018, Metal resurfacing inlay implant for osteochondral talar defects after failed previous surgery: a midterm prospective follow-up study, Am J Sports Med, 46, 1685, 10.1177/0363546518764916 Kon, 2012, New trends for knee cartilage regeneration: from cell-free scaffolds to mesenchymal stem cells, Curr Rev Musculoskelet Med, 5, 236, 10.1007/s12178-012-9135-x Kon, 2018, A multilayer biomaterial for osteochondral regeneration shows superiority vs microfractures for the treatment of osteochondral lesions in a multicentre randomized trial at 2 years, Knee Surg Sports Trauma Arthrosc, 26, 2704, 10.1007/s00167-017-4707-3 Kon, 2014, Clinical results of multilayered biomaterials for osteochondral regeneration, J Exp Orthop, 1, 10, 10.1186/s40634-014-0010-0 Leumann, 2016, Medial malleolar osteotomy for the treatment of talar osteochondral lesions: anatomical and morbidity considerations, Knee Surg Sports Trauma Arthrosc, 24, 2133, 10.1007/s00167-015-3591-y Zhou, 2020, Innovative tissue-engineered strategies for osteochondral defect repair and regeneration: current progress and challenges, Adv Health Mater, 10.1002/adhm.202001008 Boffa, 2021, Multi-layer cell-free scaffolds for osteochondral defects of the knee: a systematic review and meta-analysis of clinical evidence, J Exp Orthop, 8, 56, 10.1186/s40634-021-00377-4 Berta, 2020, Follow-up study evaluating the long term outcome of chondromimetic in the treatment of osteochondral defects in the knee, Appl Sci, 10, 5642, 10.3390/app10165642 Moher, 2009, Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement, Open Med, 3, e123 Kon, 2009, Matrix-assisted autologous chondrocyte transplantation for the repair of cartilage defects of the knee: systematic clinical data review and study quality analysis, Am J Sports Med, 37, 156S, 10.1177/0363546509351649 Drobnič, 2021, Complex osteochondral lesions of the talus treated with a novel bi-phasic aragonite-based implant, J Foot Ankle Surg, 60, 391, 10.1053/j.jfas.2020.06.028 Albano, 2017, Clinical and imaging outcome of osteochondral lesions of the talus treated using autologous matrix-induced chondrogenesis technique with a biomimetic scaffold, BMC Musculoskelet Disord, 18, 1, 10.1186/s12891-017-1679-x Kaipel, 2016, Beneficial clinical effects but limited tissue quality following osteochondral repair with a cell-free multilayered nano-composite scaffold in the talus, Foot Ankle Surg, 23, 302, 10.1016/j.fas.2016.09.003 Christensen, 2015, Poor osteochondral repair by a biomimetic collagen scaffold: 1-to 3-year clinical and radiological follow-up, Knee Surg Sports Trauma Arthrosc, 24, 2380, 10.1007/s00167-015-3538-3 Ribeiro, 2013, 3D scaffolds in talus chondral lesions–ACI/fibrin glue scaffold versus type I collagen/hydroxyapatite scaffold, Procedia Eng, 59, 133, 10.1016/j.proeng.2013.05.102 Brulc U., Drobnič M., Kolar M., Stražar K. A prospective, single-center study following operative treatment for osteochondral lesions of the talus. Foot Ankle Surg. 2021 Aug 26:S1268–7731(21)00179-X. doi:10.1016/j.fas.2021.08.008. Epub ahead of print. Lin, 2010, Effectiveness of composite bone graft substitute plugs in the treatment of chondral and osteochondral lesions of the talus, J Foot Ankle Surg, 49, 224, 10.1053/j.jfas.2010.02.008 Di Cave, 2017, Biphasic bioresorbable scaffold (TruFit Plug®) for the treatment of osteochondral lesions of talus: 6-to 8-year follow-up, Foot, 33, 48, 10.1016/j.foot.2017.05.005 Pearce, 2012, Synthetic osteochondral grafting of ankle osteochondral lesions, Foot Ankle Surg, 18, 114, 10.1016/j.fas.2011.04.001 Garcia, 2010, Treatment of osteochondral lesions of the talus with a biosynthetic scaffold: a report of four cases, J Bone Jt Surg, 92, 1774, 10.2106/JBJS.I.01470 Kitaoka, 1994, Clinical rating systems for the ankle-hindfoot, midfoot, hallux, and lesser toes, Foot Ankle Int, 15, 349, 10.1177/107110079401500701 Boonstra, 2008, Reliability and validity of the visual analogue scale for disability in patients with chronic musculoskeletal pain, Int J Rehabil Res, 31, 165, 10.1097/MRR.0b013e3282fc0f93 Tegner, 1985, Rating systems in the evaluation of knee ligament injuries, Clin Orthop Relat Res, 198, 43, 10.1097/00003086-198509000-00007 Roos, 2001, Validation of the foot and ankle outcome score for ankle ligament reconstruction, Foot Ankle Int, 22, 788, 10.1177/107110070102201004 EuroQol, 1990, EuroQol--a new facility for the measurement of health-related quality of life, Health Policy, 16, 199, 10.1016/0168-8510(90)90421-9 Brazier, 1992, Validating the SF-36 health survey questionnaire: new outcome measure for primary care, BMJ, 305, 160, 10.1136/bmj.305.6846.160 Martin, 1999, Development of the foot and ankle disability index (FADI), J Orthop Sports Phys Ther, 29, A32 Mazur, 1979, Ankle arthrodesis: long-term follow-up with gait analysis, J Bone Jt Surg Am, 61, 964, 10.2106/00004623-197961070-00002 Domsic, 1998, Ankle osteoarthritis scale, Foot Ankle Int, 19, 466, 10.1177/107110079801900708 Budiman-Mak, 2006, Theoretical model and rasch analysis to develop a revised foot function index, Foot Ankle Int, 27, 519, 10.1177/107110070602700707 Marlovits, 2004, Definition of pertinent parameters for the evaluation of articular cartilage repair tissue with high-resolution magnetic resonance imaging, Eur J Radio, 52, 310, 10.1016/j.ejrad.2004.03.014 Bedi, 2010, The maturation of synthetic scaffolds for osteochondral donor sites of the knee: an MRI and T2-mapping analysis, Cartilage, 1, 20, 10.1177/1947603509355970 Kon, 2014, Clinical results and MRI evolution of a nano-composite multilayered biomaterial for osteochondral regeneration at 5 years, Am J Sports Med, 42, 158, 10.1177/0363546513505434 Kon, 2021, Aragonite-based scaffold for the treatment of joint surface lesions in mild to moderate osteoarthritic knees: results of a 2-year multicenter prospective study, Am J Sports Med, 49, 588, 10.1177/0363546520981750 D'Ambrosi, 2019, MaioRegen osteochondral substitute for the treatment of knee defects: a systematic review of the literature, J Clin Med, 8, 783, 10.3390/jcm8060783 Verhaegen, 2015, TruFit plug for repair of osteochondral defects-where is the evidence? Systematic review of literature, Cartilage, 6, 12, 10.1177/1947603514548890 Filardo, 2021, Scaffolds for knee chondral and osteochondral defects: indications for different clinical scenarios. a consensus statement, Cartilage, 13, 1036S, 10.1177/1947603519894729 Hepple, 1999, Osteochondral lesions of the talus: a revised classification, Foot Ankle Int, 20, 789, 10.1177/107110079902001206 Giannini, 2005, Surgical treatment of osteochondral lesions of the talus in young active patients, J Bone Jt Surg Am, 87, 28 Berndt A.L., Harty M. Transchondral fractures (osteochondritis dissecans) of the talus. J Bone Joint Surg Am. 1959;41-A:988–1020. doi:10.2106/00004623–195941060-00002.