Multichain immune recognition receptor signaling: different players, same game?

Call, 2002, The organizing principle in the formation of the T cell receptor–CD3 complex, Cell, 111, 967, 10.1016/S0092-8674(02)01194-7

Sanchez, 1993, Signal transduction by immunoglobulin is mediated through Igα and Igβ, J. Exp. Med., 178, 1049, 10.1084/jem.178.3.1049

Daeron, 1997, Fc receptor biology, Annu. Rev. Immunol., 15, 203, 10.1146/annurev.immunol.15.1.203

Sigalov, 2004, Homooligomerization of the cytoplasmic domain of the T cell receptor ζ chain and of other proteins containing the immunoreceptor tyrosine-based activation motif, Biochemistry, 43, 2049, 10.1021/bi035900h

Heldin, 1995, Dimerization of cell surface receptors in signal transduction, Cell, 80, 213, 10.1016/0092-8674(95)90404-2

Boniface, 1998, Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands, Immunity, 9, 459, 10.1016/S1074-7613(00)80629-9

Thyagarajan, 2003, Polyvalent antigens stabilize B cell antigen receptor surface signaling microdomains, J. Immunol., 170, 6099, 10.4049/jimmunol.170.12.6099

Holowka, 1996, Antigen-mediated IgE receptor aggregation and signaling: a window on cell surface structure and dynamics, Annu. Rev. Biophys. Biomol. Struct., 25, 79, 10.1146/annurev.bb.25.060196.000455

Bachmann, 1999, The role of T-cell receptor dimerization in T-cell activation, Immunol. Today, 20, 568, 10.1016/S0167-5699(99)01543-1

DeFranco, 1987, B-lymphocyte signal transduction in response to anti-immunoglobulin and bacterial lipopolysaccharide, Immunol. Rev., 95, 161, 10.1111/j.1600-065X.1987.tb00504.x

Ortega, 1995, How do multichain immune recognition receptors signal? A structural hypothesis, Mol. Immunol., 32, 941, 10.1016/0161-5890(95)00070-U

Buslepp, 2003, A correlation between TCR Vα docking on MHC and CD8 dependence: implications for T cell selection, Immunity, 19, 595, 10.1016/S1074-7613(03)00269-3

Rudolph, 2002, The specificity of TCR–pMHC interaction, Curr. Opin. Immunol., 14, 52, 10.1016/S0952-7915(01)00298-9

Jensen, 1997, Qualitatively distinct signaling through T cell antigen receptor subunits, Eur. J. Immunol., 27, 707, 10.1002/eji.1830270320

Kishimoto, 1995, Physical dissociation of the TCR–CD3 complex accompanies receptor ligation, J. Exp. Med., 182, 1997, 10.1084/jem.182.6.1997

La Gruta, 2004, Architectural changes in the TCR–CD3 complex induced by MHC–peptide ligation, J. Immunol., 172, 3662, 10.4049/jimmunol.172.6.3662

Borroto, 1998, Characterization of the region involved in CD3 pairwise interactions within the T cell receptor complex, J. Biol. Chem., 273, 12807, 10.1074/jbc.273.21.12807

Torres, 2002, Convergence of experimental, computational and evolutionary approaches predicts the presence of a tetrameric form for CD3-ζ, J. Mol. Biol., 316, 375, 10.1006/jmbi.2001.5268

D'Oro, 2002, Regulation of constitutive TCR internalization by the ζ-chain, J. Immunol., 169, 6269, 10.4049/jimmunol.169.11.6269

Wang, 2002, T cell antigen receptor (TCR) transmembrane peptides colocalize with TCR, not lipid rafts, in surface membranes, Cell. Immunol., 215, 12, 10.1016/S0008-8749(02)00002-3

Enk, 2000, T cell receptor mimic peptides and their potential application in T-cell-mediated disease, Int. Arch. Allergy Immunol., 123, 275, 10.1159/000053639

Mahnke, 2003, Dendritic cells, engineered to secrete a T-cell receptor mimic peptide, induce antigen-specific immunosuppression in vivo, Nat. Biotechnol., 21, 903, 10.1038/nbt842

Wang, 2002, T-cell antigen receptor peptides inhibit signal transduction within the membrane bilayer, Clin. Immunol., 105, 199, 10.1006/clim.2002.5270

Niedergang, 1997, Peptide antigen or superantigen-induced down-regulation of TCRs involves both stimulated and unstimulated receptors, J. Immunol., 159, 1703, 10.4049/jimmunol.159.4.1703

Monks, 1998, Three-dimensional segregation of supramolecular activation clusters in T cells, Nature, 395, 82, 10.1038/25764

Legendre, 1999, Antigen-induced TCR–CD3 down-modulation does not require CD3δ or CD3γ cytoplasmic domains, necessary in response to anti-CD3 antibody, Int. Immunol., 11, 1731, 10.1093/intimm/11.11.1731

Niedergang, 1997, Differential cytosolic tail dependence and intracellular fate of T-cell receptors internalized upon activation with superantigen or phorbol ester, Res. Immunol., 148, 231, 10.1016/S0923-2494(97)80865-6

Krummel, 2000, Differential clustering of CD4 and CD3ζ during T cell recognition, Science, 289, 1349, 10.1126/science.289.5483.1349

Schaefer, 2002, The conserved process of TCR–CD3 complex down-modulation by SIV Nef is mediated by the central core, not endocytic motifs, Virology, 302, 106, 10.1006/viro.2002.1628

Schrager, 1999, HIV-1 Nef increases T cell activation in a stimulus-dependent manner, Proc. Natl. Acad. Sci. U. S. A., 96, 8167, 10.1073/pnas.96.14.8167

Xu, 1999, Induction of Fas ligand expression by HIV involves the interaction of Nef with the T cell receptor ζ chain, J. Exp. Med., 189, 1489, 10.1084/jem.189.9.1489

Arold, 2000, Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein, Protein Sci., 9, 1137, 10.1110/ps.9.6.1137

Liu, 2000, Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions, J. Virol., 74, 5310, 10.1128/JVI.74.11.5310-5319.2000

Benschop, 1999, B cell development: signal transduction by antigen receptors and their surrogates, Curr. Opin. Immunol., 11, 143, 10.1016/S0952-7915(99)80025-9

Batista, 1998, Affinity dependence of the B cell response to antigen: a threshold, a ceiling, and the importance of off-rate, Immunity, 8, 751, 10.1016/S1074-7613(00)80580-4

Batista, 2001, B cells acquire antigen from target cells after synapse formation, Nature, 411, 489, 10.1038/35078099

Vilen, 1999, Antigen-stimulated dissociation of BCR mIg from Ig-α/Ig-β: implications for receptor desensitization, Immunity, 10, 239, 10.1016/S1074-7613(00)80024-2

Vilen, 2002, Transmodulation of BCR signaling by transduction-incompetent antigen receptors: implications for impaired signaling in anergic B cells, J. Immunol., 168, 4344, 10.4049/jimmunol.168.9.4344

Bannish, 2001, Ligand-independent signaling functions for the B lymphocyte antigen receptor and their role in positive selection during B lymphopoiesis, J. Exp. Med., 194, 1583, 10.1084/jem.194.11.1583

Ortega, 1988, Possible orientational constraints determine secretory signals induced by aggregation of IgE receptors on mast cells, EMBO J., 7, 4101, 10.1002/j.1460-2075.1988.tb03304.x

Pecht, 1991, Rotational dynamics of the Fcε receptor on mast cells monitored by specific monoclonal antibodies and IgE, Biochemistry, 30, 3450, 10.1021/bi00228a015

Schweitzer-Stenner, 1994, Kinetics of Fcε RI dimer formation by specific monoclonal antibodies on mast cells, Biochemistry, 33, 8813, 10.1021/bi00195a025

Wilson, 1995, Distinct functions of the FcεR1γ and β subunits in the control of FcεR1-mediated tyrosine kinase activation and signaling responses in RBL-2H3 mast cells, J. Biol. Chem., 270, 4013, 10.1074/jbc.270.8.4013

Lin, 1996, The FcεRIβ subunit functions as an amplifier of FcεRIγ-mediated cell activation signals, Cell, 85, 985, 10.1016/S0092-8674(00)81300-8

Dombrowicz, 1998, Allergy-associated FcRβ is a molecular amplifier of IgE- and IgG-mediated in vivo responses, Immunity, 8, 517, 10.1016/S1074-7613(00)80556-7

Asai, 2000, Distinct aggregation of β- and γ-chains of the high-affinity IgE receptor on cross-linking, J. Histochem. Cytochem., 48, 1705, 10.1177/002215540004801213

Zal, 2002, Inhibition of T cell receptor–coreceptor interactions by antagonist ligands visualized by live FRET imaging of the T-hybridoma immunological synapse, Immunity, 16, 521, 10.1016/S1074-7613(02)00301-1