Multi-biofunction of antimicrobial peptide-immobilized silk fibroin nanofiber membrane: Implications for wound healing

Sen, 2009, Human skin wounds: a major and snowballing threat to public health and the economy, Wound Repair Regen., 17, 763, 10.1111/j.1524-475X.2009.00543.x

Edwards, 2004, Bacteria and wound healing, Curr. Opin. Infect. Dis., 17, 91, 10.1097/00001432-200404000-00004

Siedenbiedel, 2012, Antimicrobial polymers in solution and on surfaces: overview and functional principles, Polymers, 4, 46, 10.3390/polym4010046

Mogosanu, 2014, Natural and synthetic polymers for wounds and burns dressing, Int. J. Pharm., 463, 127, 10.1016/j.ijpharm.2013.12.015

Abrigo, 2014, Electrospun nanofibers as dressings for chronic wound care: advances, challenges, and future prospects, Macromol. Biosci., 14, 772, 10.1002/mabi.201300561

Vepari, 2007, Silk as a biomaterial, Prog. Polym. Sci., 32, 991, 10.1016/j.progpolymsci.2007.05.013

Murphy, 2009, Biomedical applications of chemically-modified silk fibroin, J. Mater. Chem., 19, 6443, 10.1039/b905802h

Gil, 2013, Functionalized silk biomaterials for wound healing, Adv. Healthc. Mater., 2, 206, 10.1002/adhm.201200192

Wang, 2009, Enzyme immobilization on electrospun polymer nanofibers: an overview, J. Mol. Catal. B-Enzym., 56, 189, 10.1016/j.molcatb.2008.05.005

Kaur, 2014, Facts and myths of antibacterial properties of silk, Biopolymers, 101, 237, 10.1002/bip.22323

Nikaido, 2009, Multidrug resistance in bacteria, Annu. Rev. Biochem., 78, 119, 10.1146/annurev.biochem.78.082907.145923

Thorsteinsson, 2003, Soft antimicrobial agents: synthesis and activity of labile environmentally friendly long chain quaternary ammonium compounds, J. Med. Chem., 46, 4173, 10.1021/jm030829z

Atiyeh, 2007, Effect of silver on burn wound infection control and healing: review of the literature, Burns, 33, 139, 10.1016/j.burns.2006.06.010

Kong, 2010, Antimicrobial properties of chitosan and mode of action: a state of the art review, Int. J. Food Microbiol., 144, 51, 10.1016/j.ijfoodmicro.2010.09.012

Mooney, 2006, Silver dressings, Plast. Reconstr. Surg., 117, 666, 10.1097/01.prs.0000200786.14017.3a

Loh, 2010, Uptake and cytotoxicity of chitosan nanoparticles in human liver cells, Toxicol. Appl. Pharmacol., 249, 148, 10.1016/j.taap.2010.08.029

Poon, 2004, In vitro cytotoxicity of silver: implication for clinical wound care, Burns, 30, 140, 10.1016/j.burns.2003.09.030

Park, 2011, The effect of particle size on the cytotoxicity, inflammation, developmental toxicity and genotoxicity of silver nanoparticles, Biomaterials, 32, 9810, 10.1016/j.biomaterials.2011.08.085

Hancock, 2006, Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies, Nat. Biotechnol., 24, 1551, 10.1038/nbt1267

Zasloff, 2002, Antimicrobial peptides of multicellular organisms, Nature, 415, 389, 10.1038/415389a

Parisien, 2008, Novel alternatives to antibiotics: bacteriophages, bacterial cell wall hydrolases, and antimicrobial peptides, J. Appl. Microbiol., 104, 1

Cleveland, 2001, Bacteriocins: safe, natural antimicrobials for food preservation, Int. J. Food Microbiol., 71, 1, 10.1016/S0168-1605(01)00560-8

Fox, 2013, Antimicrobial peptides stage a comeback, Nat. Biotechnol., 31, 379, 10.1038/nbt.2572

Wang, 2008, Structures of human host defense cathelicidin LL-37 and its smallest antimicrobial peptide KR-12 in lipid micelles, J. Biol. Chem., 283, 32637, 10.1074/jbc.M805533200

Jacob, 2013, Short KR-12 analogs designed from human cathelicidin LL-37 possessing both antimicrobial and antiendotoxic activities without mammalian cell toxicity, J. Pept. Sci., 19, 700, 10.1002/psc.2552

Mishra, 2013, Structural location determines functional roles of the basic amino acids of KR-12, the smallest antimicrobial peptide from human cathelicidin LL-37, RSC Adv., 3, 19560, 10.1039/c3ra42599a

Vandamme, 2012, A comprehensive summary of LL-37, the factotum human cathelicidin peptide, Cell. Immunol., 280, 22, 10.1016/j.cellimm.2012.11.009

Rosenfeld, 2006, Endotoxin (lipopolysaccharide) neutralization by innate immunity host-defense peptides. Peptide properties and plausible modes of action, J. Biol. Chem., 281, 1636, 10.1074/jbc.M504327200

Mookherjee, 2006, Modulation of the TLR-mediated inflammatory response by the endogenous human host defense peptide LL-37, J. Immunol., 176, 2455, 10.4049/jimmunol.176.4.2455

Tjabringa, 2003, The antimicrobial peptide LL-37 activates innate immunity at the airway epithelial surface by transactivation of the epidermal growth factor receptor, J. Immunol., 171, 6690, 10.4049/jimmunol.171.12.6690

Heilborn, 2003, The cathelicidin anti-microbial peptide LL-37 is involved in re-epithelialization of human skin wounds and is lacking in chronic ulcer epithelium, J. Invest. Dermatol., 120, 379, 10.1046/j.1523-1747.2003.12069.x

Tokumaru, 2005, Induction of keratinocyte migration via transactivation of the epidermal growth factor receptor by the antimicrobial peptide LL-37, J. Immunol., 175, 4662, 10.4049/jimmunol.175.7.4662

Shaykhiev, 2005, Human endogenous antibiotic LL-37 stimulates airway epithelial cell proliferation and wound closure, Am. J. Physiol. Lung Cell. Mol. Physiol., 289, L842, 10.1152/ajplung.00286.2004

Akiyama, 2014, The human cathelicidin LL-37 host defense peptide upregulates tight junction-related proteins and increases human epidermal keratinocyte barrier function, J. Innate Immun., 6, 739, 10.1159/000362789

Carretero, 2008, In vitro and in vivo wound healing-promoting activities of human cathelicidin LL-37, J. Invest. Dermatol., 128, 223, 10.1038/sj.jid.5701043

Ramos, 2011, Wound healing activity of the human antimicrobial peptide LL37, Peptides, 32, 1469, 10.1016/j.peptides.2011.06.005

Maher, 2006, Investigation of the cytotoxicity of eukaryotic and prokaryotic antimicrobial peptides in intestinal epithelial cells in vitro, Biochem. Pharmacol., 71, 1289, 10.1016/j.bcp.2006.01.012

Han, 2011, Antimicrobial peptides derived from different animals: comparative studies of antimicrobial properties, cytotoxicity and mechanism of action, World J. Microbiol. Biotechnol., 27, 1847, 10.1007/s11274-010-0643-9

Bacalum, 2015, Cationic antimicrobial peptides cytotoxicity on mammalian cells: an analysis using therapeutic index integrative concept, Int. J. Pept. Res. Ther., 21, 47, 10.1007/s10989-014-9430-z

Gronberg, 2011, Stability of the cathelicidin peptide LL-37 in a non-healing wound environment, Acta Derm. Venereol., 91, 511, 10.2340/00015555-1102

Li, 2014, Antimicrobial functionalization of silicone surfaces with engineered short peptides having broad spectrum antimicrobial and salt-resistant properties, Acta Biomater., 10, 258, 10.1016/j.actbio.2013.09.009

Mishra, 2014, Site specific immobilization of a potent antimicrobial peptide onto silicone catheters: evaluation against urinary tract infection pathogens, J. Mater. Chem. B, 2, 1706, 10.1039/c3tb21300e

Lim, 2015, Development of a catheter functionalized by a polydopamine peptide coating with antimicrobial and antibiofilm properties, Acta Biomater., 15, 127, 10.1016/j.actbio.2014.12.015

Gao, 2011, The biocompatibility and biofilm resistance of implant coatings based on hydrophilic polymer brushes conjugated with antimicrobial peptides, Biomaterials, 32, 3899, 10.1016/j.biomaterials.2011.02.013

Holmberg, 2013, Bio-inspired stable antimicrobial peptide coatings for dental applications, Acta Biomater., 9, 8224, 10.1016/j.actbio.2013.06.017

Lin, 2015, Multi-biofunctionalization of a titanium surface with a mixture of peptides to achieve excellent antimicrobial activity and biocompatibility, J. Mater. Chem. B, 3, 30, 10.1039/C4TB01318B

Tan, 2014, Effectiveness of antimicrobial peptide immobilization for preventing perioperative cornea implant-associated bacterial infection, Antimicrob. Agents Chemother., 58, 5229, 10.1128/AAC.02859-14

Pedrosa, 2014, Comparison of the antibacterial activity of modified-cotton with magainin I and LL-37 with potential as wound-dressings, 131

Gomes, 2015, Incorporation of antimicrobial peptides on functionalized cotton gauzes for medical applications, Carbohydr. Polym., 127, 451, 10.1016/j.carbpol.2015.03.089

Heunis, 2013, Evaluation of a nisin-eluting nanofiber scaffold to treat Staphylococcus aureus-induced skin infections in mice, Antimicrob. Agents Chemother., 57, 3928, 10.1128/AAC.00622-13

Rapsch, 2014, Identification of antimicrobial peptides and immobilization strategy suitable for a covalent surface coating with biocompatible properties, Bioconjug. Chem., 25, 308, 10.1021/bc4004469

Bai, 2008, Surface modification and properties of Bombyx mori silk fibroin films by antimicrobial peptide, Appl. Surf. Sci., 254, 2988, 10.1016/j.apsusc.2007.10.049

Gabriel, 2006, Preparation of LL-37-grafted titanium surfaces with bactericidal activity, Bioconjug. Chem., 17, 548, 10.1021/bc050091v

Hilpert, 2009, Screening and characterization of surface-tethered cationic peptides for antimicrobial activity, Chem. Biol., 16, 58, 10.1016/j.chembiol.2008.11.006

Bagheri, 2009, Immobilization reduces the activity of surface-bound cationic antimicrobial peptides with no influence upon the activity spectrum, Antimicrob. Agents Chemother., 53, 1132, 10.1128/AAC.01254-08

Dong, 2012, Structure-function relationship of antimicrobial peptide cathelicidin Pc-CATH1, Nat. Prod. Bioprospect., 2, 81, 10.1007/s13659-012-0016-1

Tossi, 2000, Amphipathic, α-helical antimicrobial peptides, Biopolymers, 55, 4, 10.1002/1097-0282(2000)55:1<4::AID-BIP30>3.0.CO;2-M

Zhang, 2002, MAPK signal pathways in the regulation of cell proliferation in mammalian cells, Cell Res., 12, 9, 10.1038/sj.cr.7290105

Efimova, 2003, A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation, 278, 34277

Sharma, 2003, P38 and ERK1/2 coordinate cellular migration and proliferation in epithelial wound healing: evidence of cross-talk activation between MAP kinase cascades, J. Biol. Chem., 278, 21989, 10.1074/jbc.M302650200