Mucosal insulin delivery systems based on complexation polymer hydrogels: effect of particle size on insulin enteral absorption

Journal of Controlled Release - Tập 97 Số 1 - Trang 115-124 - 2004
Mariko Morishita1, Takahiro Goto1, Nicholas A. Peppas2, Jeffery Joseph3, Marc C. Torjman3, Carey Munsick3, Koji Nakamura4, Tetsuo Yamagata1, Kozo Takayama1, Anthony M. Lowman4
1Department of Pharmaceutics, Hoshi University, Ebara 2-4-41, Shinagawa, Tokyo 142-8501, Japan
2Division of Pharmaceutics and Departments of Chemical and Biomedical Engineering, University of Texas at Austin, Austin, TX 78712-0231, USA
3The Artificial Pancreas Center, Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA 19107, USA
4Department of Chemical Engineering, Drexel University, Philadelphia, PA 19104 USA

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