Muconaldehyde formation from 14C-benzene in a hydroxyl radical generating system

Snyder, 1981, The biochemical toxicology of benzene, Vol. 3, 123 Goldstein, 1982, Muconaldehyde, a potential toxic intermediate of benzene metabolism, 331 Loeff, 1959, Aromatic ring opening in the presence of oxygen in irradiated solutions, Nature, 184, 901, 10.1038/184901a0 Parke, 1953, Studies in detoxification 49. The metabolism of benzene containing 14C1-benzene, Biochem. J., 54, 231, 10.1042/bj0540231 Gad-El Karim, 1985, Trans,trans-muconic acid, an open-chair urinary metabolite of benzene in mice. Quantification by high pressure liquid chromatography, Xenobiotica, 15, 211, 10.3109/00498258509045351 Witz, 1985, Short term toxicity of trans,trans-muconaldehyde, Toxicol. Appl. Pharmacol., 8,0, 511, 10.1016/0041-008X(85)90396-5 Udenfriend, 1954, Ascorbic acid in aromatic hydroxylation I. A model system for aromatic hydroxylation, J. Biol. Chem., 208, 731, 10.1016/S0021-9258(18)65598-X Brodie, 1954, Ascorbic acid in aromatic hydroxylation. II. Products formed by reaction of substrates with ascorbic acid, ferrous ion, and oxygen, J. Biol. Chem., 208, 741, 10.1016/S0021-9258(18)65599-1 Walling, 1975, Fenton's reagent revisited, Accts. Chem. Res., 8, 125, 10.1021/ar50088a003 Cohen, 1983, Activation of molecular oxygen during a Fenton reactions: A study with 18O2, Vol. 1, 74 Karrer, 1949, Muconsauredialdehyde und octadien-(3,5)-dion)2,7, Helv. chim. Acta, 32, 1013, 10.1002/hlca.19490320351 Davis, 1977, Benzene oxide-oxepin. Oxidation to muconaldehyde, J. Chem. Soc. Perkin Trans., 1, 1346, 10.1039/P19770001346 Sinnhuber, 1958, 2-Thiobarbituric acid method for the measurement of rancidity in fishery products, Food Technol., 12, 19 Witz, 1983, The reaction of 2-thiobarbituric acid with trans,trans-muconaldehyde, a potential benzene metabolite, Toxicol. Letters 18, Suppl., 1, 93, 10.1016/0378-4274(83)90466-6 Latriano, 1985, Determination of muconaldehyde, a potential metabolite of benzene, by high pressure liquid chromatography, Toxicologist, 5, 539 Witz, 1985, Adduct formation of toxic alpha, beta-unsaturated aldehydes with 2-thiobarbituric acid, Toxicologist, 5, 919 Daniels, 1956, Chemical action of ionizing radiation in solution, part XV. Effect of molecular oxygen in the irradiation of acqueous benzene solutions with X-rays, J. Chem. Soc., 832, 10.1039/jr9560000832 Srinivasan, 1969, On the nature of the products of gamma radiolysis of aerated aqueous solutions of benzene, J. Phys. Chem., 73, 2071, 10.1021/j100726a076 Johansson, 1983, Hydroxyl radical-mediated, cytochrome P-450-dependent metabolic activation of benzene in microsomes and reconstituted enzyme systems from rabbit liver, J. Biol. Chem., 258, 7311, 10.1016/S0021-9258(18)32179-3