Mrc1 and Tof1 Promote Replication Fork Progression and Recovery Independently of Rad53

Molecular Cell - Tập 19 - Trang 699-706 - 2005
Hélène Tourrière1, Gwennaëlle Versini1, Violeta Cordón-Preciado2, Constance Alabert1, Philippe Pasero1
1Institute of Human Genetics, Centre National de la Recherche Scientifique, UPR 1142, 141 rue de la Cardonille, 34396 Montpellier Cedex 5, France
2Centro de Investigación del Cáncer, Campus Miguel de Unamuno, Universidad de Salamanca-CSIC, 37007 Salamanca, Spain

Tài liệu tham khảo

Alcasabas, 2001, Mrc1 transduces signals of DNA replication stress to activate Rad53, Nat. Cell Biol., 3, 958, 10.1038/ncb1101-958 Benard, 2001, DNA replication-dependent formation of joint DNA molecules in Physarum polycephalum, Mol. Cell, 7, 971, 10.1016/S1097-2765(01)00237-4 Bjergbaek, 2005, Mechanistically distinct roles for Sgs1p in checkpoint activation and replication fork maintenance, EMBO J., 24, 405, 10.1038/sj.emboj.7600511 Brewer, 1988, A replication fork barrier at the 3′ end of yeast ribosomal RNA genes, Cell, 55, 637, 10.1016/0092-8674(88)90222-X Calzada, 2005, Molecular anatomy and regulation of a stable replisome at a paused eukaryotic DNA replication fork, Genes Dev., 19, 1905, 10.1101/gad.337205 Cobb, 2003, DNA polymerase stabilization at stalled replication forks requires Mec1 and the RecQ helicase Sgs1, EMBO J., 22, 4325, 10.1093/emboj/cdg391 Cobb, 2004, Redundancy, insult-specific sensors and thresholds: unlocking the S-phase checkpoint response, Curr. Opin. Genet. Dev., 14, 292, 10.1016/j.gde.2004.04.001 Codlin, 2003, Complex mechanism of site-specific DNA replication termination in fission yeast, EMBO J., 22, 3431, 10.1093/emboj/cdg330 Dalgaard, 2001, A DNA replication-arrest site RTS1 regulates imprinting by determining the direction of replication at mat1 in S. pombe, Genes Dev., 15, 2060, 10.1101/gad.200801 Desany, 1998, Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway, Genes Dev., 12, 2956, 10.1101/gad.12.18.2956 Foss, 2001, Tof1p regulates DNA damage responses during S phase in Saccharomyces cerevisiae, Genetics, 157, 567, 10.1093/genetics/157.2.567 Gilbert, 2001, Budding yeast Rad9 is an ATP-dependent Rad53 activating machine, Mol. Cell, 8, 129, 10.1016/S1097-2765(01)00267-2 Ivessa, 2000, The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA, Cell, 100, 479, 10.1016/S0092-8674(00)80683-2 Ivessa, 2003, The Saccharomyces cerevisiae helicase Rrm3p facilitates replication past nonhistone protein-DNA complexes, Mol. Cell, 12, 1525, 10.1016/S1097-2765(03)00456-8 Katou, 2003, S-phase checkpoint proteins Tof1 and Mrc1 form a stable replication-pausing complex, Nature, 424, 1078, 10.1038/nature01900 Krings, 2004, swi1- and swi3-dependent and independent replication fork arrest at the ribosomal DNA of Schizosaccharomyces pombe, Proc. Natl. Acad. Sci. USA, 101, 14085, 10.1073/pnas.0406037101 Kumagai, 2000, Claspin, a novel protein required for the activation of Chk1 during a DNA replication checkpoint response in Xenopus egg extracts, Mol. Cell, 6, 839, 10.1016/S1097-2765(05)00092-4 Lambert, 2005, Gross chromosomal rearrangements and elevated recombination at an inducible site-specific replication fork barrier, Cell, 121, 689, 10.1016/j.cell.2005.03.022 Lengronne, 2001, Monitoring S phase progression globally and locally using BrdU incorporation in TK(+) yeast strains, Nucleic Acids Res., 29, 1433, 10.1093/nar/29.7.1433 Lopes, 2001, The DNA replication checkpoint response stabilizes stalled replication forks, Nature, 412, 557, 10.1038/35087613 Lopes, 2003, Branch migrating sister chromatid junctions form at replication origins through Rad51/Rad52-independent mechanisms, Mol. Cell, 12, 1499, 10.1016/S1097-2765(03)00473-8 Michalet, 1997, Dynamic molecular combing: stretching the whole human genome for high-resolution studies, Science, 277, 1518, 10.1126/science.277.5331.1518 Noguchi, 2004, Swi1 and Swi3 are components of a replication fork protection complex in fission yeast, Mol. Cell. Biol., 24, 8342, 10.1128/MCB.24.19.8342-8355.2004 Nyberg, 2002, Toward maintaining the genome: DNA damage and replication checkpoints, Annu. Rev. Genet., 36, 617, 10.1146/annurev.genet.36.060402.113540 Osborn, 2003, Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53, Genes Dev., 17, 1755, 10.1101/gad.1098303 Pasero, 2002, Single-molecule analysis reveals clustering and epigenetic regulation of replication origins at the yeast rDNA locus, Genes Dev., 16, 2479, 10.1101/gad.232902 Rothstein, 2000, Replication fork pausing and recombination or “gimme a break”, Genes Dev., 14, 1, 10.1101/gad.14.1.1 Santocanale, 1998, A Mec1- and Rad53-dependent checkpoint controls late-firing origins of DNA replication, Nature, 395, 615, 10.1038/27001 Szyjka, 2005, Mrc1 is required for normal progression of replication forks throughout chromatin in S. cerevisiae, Mol. Cell, 19, 691, 10.1016/j.molcel.2005.06.037 Tanaka, 2001, Mrc1 channels the DNA replication arrest signal to checkpoint kinase Cds1, Nat. Cell Biol., 3, 966, 10.1038/ncb1101-966 Tercero, 2003, A central role for DNA replication forks in checkpoint activation and response, Mol. Cell, 11, 1323, 10.1016/S1097-2765(03)00169-2 Tong, 2004, Global mapping of the yeast genetic interaction network, Science, 303, 808, 10.1126/science.1091317 Torres, 2004, Saccharomyces cerevisiae Rrm3p DNA helicase promotes genome integrity by preventing replication fork stalling: viability of rrm3 cells requires the intra-S-phase checkpoint and fork restart activities, Mol. Cell. Biol., 24, 3198, 10.1128/MCB.24.8.3198-3212.2004 Versini, 2003, The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication, EMBO J., 22, 1939, 10.1093/emboj/cdg180 Weitao, 2003, Evidence that yeast SGS1, DNA2, SRS2, and FOB1 interact to maintain rDNA stability, Mutat. Res., 532, 157, 10.1016/j.mrfmmm.2003.08.015 Wu, 1995, Rapid DNA preparation for 2D gel analysis of replication intermediates, Nucleic Acids Res., 23, 3997, 10.1093/nar/23.19.3997