Morphology, distribution and its significance of intrahepatic HBV DNA in liver disease: A study by in situ hybridization

Bonino F. The importance of hepatitis B vival DNA in serum and liver. J Hepatol 1986; 3:136–41.

Erechot C, et al. Hepatitis B virus DNA in patients with chronic liver disease and negative tests fcr hepatitis B surface antigen. N Eng J Med 1985;312: 270–6.

International Group. Acute and chronic hepatitis revised. Lancet 1977;I:914–7.

Negro F, et al. Detection of HBV-DNA by in situ hybridization using a biotinlabeled probe. J Med Virol 1985; 15: 373–82.

Rijntjes PJM, et al. Hepatitis B virus DNA detected in formalin-fixed liver specimens and its relation to serologic markers and histopathologic features in chronic liver disease. AJP 1985:120: 411–8.

Blum HE, et al. Molecular pathogenesis of hepatitis B viral infection: simultaneous detection of viral DNA and pathogens in paraffin-embedded liver sections. Lancet 1984;I:771–5.

Michitaka K, et al. Change of hepatitis B virus DNA distribution associated with the progression of chronic hepatitis. Liver 1988; 8:247–53.

Herrmann G, Hubner K. In situ hybridization with HBV-cDNA as a sensitive method for the diagnosis of hepatitis B infection in persistent acute hepatitis. Hepatogastroenterology 1987; 34:148–51.

Gowans E, et al. Detection of hepatitis B virus DNA sequences in infected hepatocytes by in situ hybridization. J Med Virol 1981; 8:67–78.

Burrell CJ, et al. Correlation between liver histology and markers of hepatitis B virus replication in infected patients: a study by in situ hybridization. Hepatology 1984; 4:20–4.