Morphologic and cytochemical identification of microperoxisomes in human and non-human primate placental trophoblast
Tóm tắt
Human and non-human primate placental villi (near term) were incubated in an alkaline 3,3′ diamino benzidine (DAB) medium to identify the distribution of microperoxisomes in these tissues. Catalase-positive microperoxisomes were present in small numbers in cytotrophoblast, but were virtually absent from syncytiotrophoblast. Microperoxisomes were roughly circular in shape and about 0.2–0.3 μm in diameter. They always had a close association with an element of agranular endoplasmic reticulum. The function of microperoxisomes in placenta, as in many other tissues, is uncertain. What-ever their function, they are presumably more important in cytotrophoblast metabolism than in syncytium.
Tài liệu tham khảo
Black VH, Bogart BI (1973) Peroxisomes in inner adrenocortical cells of fetal and adult guinea pigs. J Cell Biol 57:345–358
deDuve C (1973) Biochemical studies on the occurrence, biogenesis and life history of mammalian peroxisomes. J Histochem Cytochem 21:941–948
Familiari G, Franchitto G, Correr S, Motta P (1979) Microperoxisomes in steroidogenic cells of the rat ovary-interstitial, thecal and luteal cells. Experientia 35:1503–1505
Gemmell RT, Stacy BD (1979) Ultrastructural study of granules in the corpora lutea of several mammalian species. Am J Anat 155:1–14
Gulyas BJ, Yuan LC (1975) Microperoxisomes in the late pregnancy corpus luteum of rhesus monkeys (Macaca mulatta). J Histochem Cytochem 23:359–368
Gulyas BF, Yuan LC (1977) Association of microperoxisomes with the endoplasmic reticulum in granulosa lutein cells of the rhesus monkey. Cell Tissue Res 179:357–366
Hand AR (1973) Morphologic and cytochemical identification of peroxisomes in the rat parotid and other exocrine glands. J Histochem Cytochem 21:131–141
Herzog V, Fahimi HD (1974) Microbodies (peroxisomes) containing catalase in myocardium: morphological and biochemical evidence. Science 185:271–273
Herzog V, Fahimi HD (1975) Identification of peroxisomes (microbodies) in mouse myocardium. J Mol Cell Cardiol 8:271–273
Hruban Z, Rechncigl M (1969) Microbodies and related particles. Int Rev Cytol Suppl 1:1–296
Kodr GS, Siler-Kodr T (1978) Localization of luteinizing hormone-releasing factor in the human placenta. Fertil Steril 29:523–526
Lazarow PB (1978) Rat liver peroxisomes catalyze the β-oxidation of fatty acids. J Biol Chem 253:1522–1528
Lazarow PB, deDuve C (1976) A fatty acyl-CoA oxidizing system in rat liver peroxisomes: Enhancement by clofibrate, a hypolipidemic drug. Proc Natl Acad Sci USA 73:2043–2046
Lin TJ, Lin SL, Erlenmeyer F, Line IT, Underwood R, Billiar RB, Little B (1972) Progesterone production rates during the third trimester of pregnancy in normal women, diabetic women, and women with abnormal glucose tolerance. J Clin Endocrinol Metab 34:287–297
Maniscalco W, Warshaw JB (1978) Cellular energy metabolism during fetal and perinatal development. In: Sinclair JC (ed) Temperature regulation and energy metabolism in the newborn. Grune & Stratton, New York, pp 1–38
Margoliash E, Novogrodsky A, Schejter A (1960) Irreversible reaction of 3-amino-1:2:4-triazole and related inhibitors with the protein of catalase. Biochem J 74:339–350
Masters C, Holmes R (1977) Peroxisomes: New aspects of cell physiology and biochemistry. Physiol Rev 57:816–882
Nelson DM, Enders AC, King BF (1978a) Cytological events involved in protein synthesis in cellular and syncytial trophoblast of human placenta. An electron microscope autoradiographic study of (3H) leucine incorporation. J Cell Biol 76:400–417
Nelson DM, Enders AC, King BF (1978b) Cytological events involved in glycoprotein synthesis in cellular and syncytial trophoblast of human placenta: An electron microscope autoradiographic study of (3H) galactose incorporation. J Cell Biol 76:418–429
Novikoff AB, Novikoff PM, Davis C, Quintana N (1972) Studies on microperoxisomes. II. A cytochemical method for light and electron microscopy. J Histochem Cytochem 20:1006–1023
Novikoff AB, Novikoff PM, Quintana N, Davis C (1973a) Studies on microperoxisomes. IV. Interrelations of microperoxisomes, endoplasmic reticulum and lipofuscin granules. J Histochem Cytochem 21:1010–1020
Novikoff PM, Novikoff AB, Davis C, Quintano N (1973b) Studies on microperoxisomes. V. Are microperoxisomes ubiquitous in mammalian cells? J Histochem Cytochem 21:373–755
Paavola LG, Boyd CO (1981) Cytoplasmic granules in luteal cells of pregnant and non-pregnant guinea pigs. A cytochemical study. Anat Rec 201:127–140
Reddy J, Svoboda D (1972a) Microbodies (peroxisomes) identification in interstitial cells of the testis. J Histochem Cytochem 20:140–142
Reddy J, Svoboda D (1972b) Microbodies (peroxisomes) in the interstitial cells of rodent testes. Lab Invest 26:657–665
Russo JJ, Black VH (1980) Peroxisomes in guinea pig adrenocortical cells: Enzymatic characterization and responsiveness to adrenocorticotrophic hormone (ACTH). J Cell Biol 87:168a
Russo JJ, Black VH (1981) Isolation of a peroxisome-enriched fraction from the guinea pig adrenal. Anat Rec 199:221A
Tolbert NE (1981) Metabolic pathways in peroxisomes and glyoxysomes. Annu Rev Biochem 50:133–157
Warshaw JB (1981) Control of fatty acid metabolism during development. In: Physiological and biochemical basis for perinatal medicine. S Karger, Basel, pp 101–107