Moringa rivae leaf extracts attenuate Complete Freund’s adjuvant-induced arthritis in Wistar rats via modulation of inflammatory and oxidative stress biomarkers

Inflammopharmacology - Tập 28 Số 1 - Trang 139-151 - 2020
Ammara Saleem1, Mohammad Saleem1,2, Muhammad Furqan Akhtar3, Muhammad Shahzad4, Sidrah Saleem5
1Department of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University Faisalabad, Faisalabad, Pakistan
2Department of Pharmacology, University College of Pharmacy, University of the Punjab, Lahore, Pakistan
3Riphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, Pakistan
4Department of Pharmacology, University of Health Sciences, Lahore, Pakistan
5Department of Immunology, University of Health Sciences Lahore, Pakistan

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Adeyemi WJ, Olayaki LA (2018) Diclofenac–induced hepatotoxicity: low dose of omega-3 fatty acids have more protective effects. Toxicol Rep 5:90–95

Afonso V, Champy R, Mitrovic D, Collin P, Lomri A (2007) Reactive oxygen species and superoxide dismutases: role in joint diseases. Joint Bone Spine 74:324–329

Akhtar MF, Ashraf M, Anjum AA, Javeed A, Sharif A, Saleem A, Akhtar B (2016) Textile industrial effluent induces mutagenicity and oxidative DNA damage and exploits oxidative stress biomarkers in rats. Environ Toxicol Pharmacol 41:180–186

Chandrasekaran M, Senthilkumar A, Venkatesalu V (2011) Antibacterial and antifungal efficacy of fatty acid methyl esters from the leaves of Sesuvium portulacastrum L. Eur Rev Med Pharmacol Sci 15:775–780

Coura CO et al (2015) Mechanisms involved in the anti-inflammatory action of a polysulfated fraction from Gracilaria cornea in rats. PLoS ONE 10:e0119319

Di Ming Y, Zhou Z-W, Guang Li C, Zhou S-F (2011) Current and future therapeutic targets of rheumatoid arthritis. AntiInflamm Antiallerg Agents Med Chem 10:92–120

Fattahi MJ, Mirshafiey A (2012) Prostaglandins and rheumatoid arthritis. Arthritis 2012:1–7

Foyet HS, Tsala DE, Bodo JZE, Carine AN, Heroyne LT, Oben EK (2015) Anti-inflammatory and anti-arthritic activity of a methanol extract from Vitellaria paradoxa stem bark. Pharmacog Res 7:367–376

Gopalakrishnan L, Doriya K, Kumar DS (2016) Moringa oleifera: a review on nutritive importance and its medicinal application. Food Sci Hum Wellness 5:49–56

Ishtiaq S, Ahmad M, Hanif U, Akbar S, Kamran SH (2014) Phytochemical and in vitro antioxidant evaluation of different fractions of Amaranthus graecizans subsp. silvestris (Vill.). Brenan Asian Pac J Trop Med 7:S342–S347

Issekutz AC, Sapru K (2008) Modulation of adjuvant arthritis in the rat by 2-methoxyestradiol: an effect independent of an anti-angiogenic action. Int Immunopharmacol 8:708–716

Kalaiselvan S, Rasool MK (2016) Triphala herbal extract suppresses inflammatory responses in LPS-stimulated RAW 264.7 macrophages and adjuvant-induced arthritic rats via inhibition of NF-κB pathway. J Immunotoxicol 13:509–525

Karthivashan G, Tangestani Fard M, Arulselvan P, Abas F, Fakurazi S (2013) Identification of bioactive candidate compounds responsible for oxidative challenge from hydro-ethanolic extract of Moringa oleifera leaves. J Food Sci 78:C1368–C1375

Kumar V, Verma A, Ahmed D, Sachan NK, Anwar F, Mujeeb M (2013) Fostered antiarthritic upshot of moringa oleifera lam. stem bark extract in diversely induced arthritis in wistar rats with plausible mechanism. Int J Pharm Sci Res 4:3894–3901

Lawrence T (2009) The nuclear factor NF-κB pathway in inflammation. Cold Spring Harbor Persp Biol 1:11

Miller SC et al (2010) Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action. Biochem Pharmacol 79:1272–1280

Moon S-J et al (2013) Periarticular osteoporosis is a prominent feature in early rheumatoid arthritis: estimation using shaft to periarticular bone mineral density ratio. J Korean Med Sci 28:287–294

Mueller SD et al (2016) Anti-inflammatory and antioxidant activities of aqueous extract of Cecropia glaziovii leaves. J Ethnopharmacol 185:255–262

Oyeleke SA, Ajayi AM, Umukoro S, Aderibigbe A, Ademowo OG (2018) Anti-inflammatory activity of Theobroma cacao L stem bark ethanol extract and its fractions in experimental models. J Ethnopharmacol 222:239–248

Padayachee B, Baijnath H (2012) An overview of the medicinal importance of Moringaceae. J Med Plants Res 6:5831–5839

Rohloff J (2015) Analysis of phenolic and cyclic compounds in plants using derivatization techniques in combination with GC–MS-based metabolite profiling. Molecules 20:3431–3462

Ruan Q, Zhao C, Ye Z, Ruan J, Xie Q, Xie W (2015) Effect and possible mechanism of monocyte-derived VEGF on monocyte–endothelial cellular adhesion after electrical burns. Burns 41:825–832

Saleem A, Saleem M, Akhtar MF (2018) Antioxidant and anti-inflammatory and antiarthritic potential of Moringa rivae: an ethnomedicinal plant of Moringaceae family. S Afr J Bot (In press)

Sano H (2011) the role of lipid mediators in the phathogenesis of rheumatoid arthritis. Inflamm Regen 31:151–156

Scheel AK et al (2006) Prospective 7 year follow up imaging study comparing radiography, ultrasonography, and magnetic resonance imaging in rheumatoid arthritis finger joints. Ann Rheum Dis 65:595–600

Shabbir A, Shahzad M, Ali A, Zia-ur-Rehman M (2014) Anti-arthritic activity of N′-[(2,4-dihydroxyphenyl) methylidene]-2-(3,4-dimethyl-5, 5-dioxidopyrazolo [4,3-c][1, 2] benzothiazin-1 (4H)-yl) acetohydrazide. Eur J Pharmacol 738:263–272

Shabbir A, Shahzad M, Ali A, Zia-ur-Rehman M (2016) Discovery of new benzothiazine derivative as modulator of pro-and anti-inflammatory cytokines in rheumatoid arthritis. Inflammation 39:1918–1929

Shabbir A, Batool SA, Basheer MI, Shahzad M, Sultana K, Tareen RB, Iqbal J (2018) Ziziphora clinopodioides ameliorated rheumatoid arthritis and inflammatory paw edema in different models of acute and chronic inflammation. Biomed Pharmacother 97:1710–1721

Sharif A, Ashraf M, Javeed A, Anjum AA, Akhtar MF, Akhtar B, Saleem A (2016) Oxidative stress responses in Wistar rats on subacute exposure to pharmaceutical wastewater. Environ Sci Pollut Res 23:24158–24165

Srirangan S, Choy EH (2010) The role of interleukin 6 in the pathophysiology of rheumatoid arthritis. Therap Adv Musculoskeletal Dis 2:247–256

Taksande BG, Gawande DY, Chopde CT, Umekar MJ, Kotagale NR (2017) Agmatine ameliorates adjuvant induced arthritis and inflammatory cachexia in rats. Biomed Pharmacother 86:271–278

Thite AT, Patil RR, Naik SR (2014) Anti-arthritic activity profile of methanolic extract of Ficus bengalensis: comparison with some clinically effective drugs. Biomed Aging Pathol 4:207–217

Uroos M, Abbas Z, Sattar S, Umer N, Shabbir A, Sharif A (2017) Nyctanthes arbor-tristis ameliorated FCA-induced experimental arthritis: a comparative study among different extracts. Evid Based Complement Altern Med 2017:1–14

Voon F-L et al (2017) Cardamonin (2′, 4′-dihydroxy-6′-methoxychalcone) isolated from Boesenbergia rotunda (L.) Mansf. inhibits CFA-induced rheumatoid arthritis in rats. Eur J Pharmacol 794:127–134

Wang S, Wang Y, Liu X, Guan L, Yu L, Zhang X (2016) Anti-inflammatory and anti-arthritic effects of taraxasterol on adjuvant-induced arthritis in rats. J Ethnopharmacol 187:42–48

Yu F-R, Lian X-Z, Guo H-Y, McGuire PM, Li R-D, Wang R, Yu F-H (2005) Isolation and characterization of methyl esters and derivatives from Euphorbia kansui (Euphorbiaceae) and their inhibitory effects on the human SGC-7901 cells. J Pharm Pharm Sci 8:528–535

Yu Y et al (2018) Anti-arthritic activities of ethanol extracts of Circaea mollis Siebold & Zucc. (whole plant) in rodents. J Ethnopharmacol 225:359–366

Zhu S, Li J, Bing Y, Yan W, Zhu Y, Xia B, Chen M (2015) Diet-induced hyperhomocysteinaemia increases intestinal inflammation in an animal model of colitis. J Crohn’s Colitis 9:708–719