Monosodium urate crystals induced ICAM-1 expression and cell–cell adhesion in renal mesangial cells: Implications for the pathogenesis of gouty nephropathy

Stamp, 2013, Gout and its comorbidities: implications for therapy, Rheumatology (Oxford), 52, 34, 10.1093/rheumatology/kes211 Kuo, 2015, Global epidemiology of gout: prevalence, incidence and risk factors, Nat Rev Rheumatol, 11, 649, 10.1038/nrrheum.2015.91 Kuo, 2016, Comorbidities in patients with gout prior to and following diagnosis: case-control study, Ann Rheum Dis, 75, 210, 10.1136/annrheumdis-2014-206410 Mazzali, 2001, Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism, Hypertension, 38, 1101, 10.1161/hy1101.092839 Mount, 2013, The kidney in hyperuricemia and gout, Curr Opin Nephrol Hypertens, 22, 216, 10.1097/MNH.0b013e32835ddad2 Desai, 2017, Molecular pathophysiology of gout, Trends Mol Med, 23, 756, 10.1016/j.molmed.2017.06.005 Schlondorff, 1996, Roles of the mesangium in glomerular function, Kidney Int, 49, 1583, 10.1038/ki.1996.229 Radeke, 1992, The inflammatory function of renal glomerular mesangial cells and their interaction with the cellular immune system, Clin Investig, 70, 825, 10.1007/BF00180754 Wuthrich, 1990, Intercellular adhesion molecule-1 (ICAM-1) expression is upregulated in autoimmune murine lupus nephritis, Am J Pathol, 136, 441 Arrizabalaga, 2001, Renal expression of intercellular adhesion molecule-1 in immunoglobulin A nephropathy: tubulointerstitial injury and prognosis, Virchows Arch Int J Pathol, 439, 27, 10.1007/s004280100443 Long, 2011, ICAM-1: getting a grip on leukocyte adhesion, J Immunol, 186, 5021, 10.4049/jimmunol.1100646 Scholer, 2008, Intercellular adhesion molecule-1-dependent stable interactions between T cells and dendritic cells determine CD8+ T cell memory, Immunity, 28, 258, 10.1016/j.immuni.2007.12.016 Rincon, 2003, Increased production of chemotactic cytokines and elevated proliferation and expression of intercellular adhesion molecule-1 in rat mesangial cells treated with erythrogenic toxin type B and its precursor isolated from nephritogenic streptococci, Nephrol Dial Transplant, 18, 1072, 10.1093/ndt/gfg109 Ikezumi, 2003, Adoptive transfer studies demonstrate that macrophages can induce proteinuria and mesangial cell proliferation, Kidney Int, 63, 83, 10.1046/j.1523-1755.2003.00717.x Holzinger, 2014, Myeloid-related proteins 8 and 14 contribute to monosodium urate monohydrate crystal-induced inflammation in gout, Arthritis Rheumatol, 66, 1327, 10.1002/art.38369 Choe, 2014, Enhanced p62 expression through impaired proteasomal degradation is involved in caspase-1 activation in monosodium urate crystal-induced interleukin-1b expression, Rheumatology (Oxford), 53, 1043, 10.1093/rheumatology/ket474 Dikshtein, 1986, Morphological changes in the kidney glomeruli in gout, Arkh Patol, 48, 54 Lee, 2009, Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta, Osteoarthr Cartil, 17, 91, 10.1016/j.joca.2008.05.010 Lin, 2012, PKCdelta signalling regulates SR-A and CD36 expression and foam cell formation, Cardiovasc Res, 95, 346, 10.1093/cvr/cvs189 Ho, 2005, Dengue virus type 2 antagonizes IFN-alpha but not IFN-gamma antiviral effect via down-regulating Tyk2-STAT signaling in the human dendritic cell, J Immunol, 174, 8163, 10.4049/jimmunol.174.12.8163 Amaral, 2012, NLRP3 inflammasome-mediated neutrophil recruitment and hypernociception depend on leukotriene B(4) in a murine model of gout, Arthritis Rheum, 64, 474, 10.1002/art.33355 Giamarellos-Bourboulis, 2009, Crystals of monosodium urate monohydrate enhance lipopolysaccharide-induced release of interleukin 1 beta by mononuclear cells through a caspase 1-mediated process, Ann Rheum Dis, 68, 273, 10.1136/ard.2007.082222 Mylona, 2012, Enhanced interleukin-1beta production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals, Arthritis Res Ther, 14, 10.1186/ar3898 di Giovine, 1991, Urate crystals stimulate production of tumor necrosis factor alpha from human blood monocytes and synovial cells. Cytokine mRNA and protein kinetics, and cellular distribution, J Clin Investig, 87, 1375, 10.1172/JCI115142 Rock, 2013, Uric acid as a danger signal in gout and its comorbidities, Nat Rev Rheumatol, 9, 13, 10.1038/nrrheum.2012.143 Chhana, 2014, Structural joint damage in gout, Rheum Dis Clin N Am, 40, 291, 10.1016/j.rdc.2014.01.006 Xiao, 2015, Soluble monosodium urate, but not its crystal, induces toll like receptor 4-dependent immune activation in renal mesangial cells, Mol Immunol, 66, 310, 10.1016/j.molimm.2015.03.250 Brady, 1992, Chemoattractants provoke monocyte adhesion to human mesangial cells and mesangial cell injury, Kidney Int, 42, 480, 10.1038/ki.1992.312 Okada, 2003, Intercellular adhesion molecule-1-deficient mice are resistant against renal injury after induction of diabetes, Diabetes, 52, 2586, 10.2337/diabetes.52.10.2586 Shi, 2003, Molecular identification of a danger signal that alerts the immune system to dying cells, Nature, 425, 516, 10.1038/nature01991 Ghaemi-Oskouie, 2011, The role of uric acid as an endogenous danger signal in immunity and inflammation, Curr Rheumatol Rep, 13, 160, 10.1007/s11926-011-0162-1 Martinon, 2009, The inflammasomes: guardians of the body, Annu Rev Immunol, 27, 229, 10.1146/annurev.immunol.021908.132715 Qing, 2013, Association of TLR4 Gene rs2149356 polymorphism with primary gouty arthritis in a case-control study, PLoS One, 8, 10.1371/journal.pone.0064845 Xiao, 2015, Soluble uric acid increases NALP3 inflammasome and interleukin-1beta expression in human primary renal proximal tubule epithelial cells through the Toll-like receptor 4-mediated pathway, Int J Mol Med, 35, 1347, 10.3892/ijmm.2015.2148 Wang, 2012, Involvement of mitogen-activated protein kinases and peroxisome proliferator-activated receptor gamma in monosodium urate crystal-induced vascular cell adhesion molecule 1 expression in human rheumatoid arthritis synovial fibroblasts, Int J Mol Med, 29, 877 Tsai, 2013, Zoledronate attenuates angiotensin II-induced abdominal aortic aneurysm through inactivation of Rho/ROCK-dependent JNK and NF-kappaB pathway, Cardiovasc Res, 100, 501, 10.1093/cvr/cvt230 Wu, 2016, Folic acid reverses uric acid crystal-induced surface OAT1 internalization by inhibiting RhoA activity in uric acid nephropathy, Mol Med Rep, 13, 2385, 10.3892/mmr.2016.4837