Monomeric GLP-1/GIP/glucagon triagonism corrects obesity, hepatosteatosis, and dyslipidemia in female mice

Molecular Metabolism - Tập 6 Số 5 - Trang 440-446 - 2017
Sigrid Jall1,2, Stephan Sachs2,3, Christoffer Clemmensen1,4,2, Brian Finan1,4,2, Frauke Neff5,6, Richard D. DiMarchi7, Matthias H. Tschöp1,4,2, Timo D. Müller1,4,2, Susanna M. Hofmann4,8,3
1Division of Metabolic Diseases, Department of Medicine, Technische Universität München, 80333 Munich, Germany
2Institute for Diabetes and Obesity, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany
3Medizinische Klinik und Poliklinik IV, Klinikum der LMU, 80336 München, Germany
4German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany
5German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany
6Institute of Pathology, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany
7Department of Chemistry, Indiana University, Bloomington IN 47405, USA
8Institute for Diabetes and Regeneration, Helmholtz Diabetes Center at Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), 85764 Neuherberg, Germany

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