Mometasone furoate and fluticasone furoate are equally effective in restoring nasal epithelial barrier dysfunction in allergic rhinitis

World Allergy Organization Journal - Tập 14 - Trang 100585 - 2021
Maria Doulaptsi1,2, Tine Wils2, Peter W. Hellings2,3,4,5, Katleen Martens2, Ricard Farré6, Maria Vicario7, Wytske Fokkens4, Emmanuel Prokopakis1, Brecht Steelant1,2
1Department of Otorhinolaryngology, Head and Neck Surgery, University of Crete School of Medicine, Heraklion, Crete, Greece
2KU Leuven Department of Microbiology, Immunology and Transplantation, Allergy and Clinical Immunology Research group, Leuven, Belgium.
3University Hospitals Leuven, Clinical Department of Otorhinolaryngology, Head and Neck Surgery, Leuven, Belgium.
4Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
5University of Ghent, Department of Otorhinolaryngology, Laboratory of Upper Airways Research, Ghent, Belgium.
6KU Leuven, Department of Chronic Diseases, Metabolism and Ageing, Translational Research Center for Gastrointestinal Disorders, Leuven, Belgium.
7Digestive Diseases Research Unit, Department of Gastroenterology, Institut de Recerca Vall d’Hebron, Hospital Universitari Vall d’Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain

Tài liệu tham khảo

Steelant, 2016, Impaired barrier function in patients with house dust mite-induced allergic rhinitis is accompanied by decreased occludin and zonula occludens-1 expression, J Allergy Clin Immunol, 137, 1043, 10.1016/j.jaci.2015.10.050

Greiner, 2011, Allergic rhinitis, Lancet, 378, 2112, 10.1016/S0140-6736(11)60130-X

Kielgast, 2016, Glucocorticoids regulate tight junction permeability of lung epithelia by modulating claudin 8, Am J Respir Cell Mol Biol, 54, 707, 10.1165/rcmb.2015-0071OC

Brunton, 2007, Treatment options for the management of perennial allergic rhinitis, with a focus on intranasal corticosteroids, South Med J, 100, 701, 10.1097/SMJ.0b013e3180485560

Fokkens, 2012, No mucosal atrophy and reduced inflammatory cells: active-controlled trial with yearlong fluticasone furoate nasal spray, Am J Rhinol Allergy, 26, 36, 10.2500/ajra.2012.26.3675

Krohn, 2020, Nasal epithelial barrier dysfunction increases sensitization and mast cell degranulation in the absence of allergic inflammation, Allergy, 75, 1155, 10.1111/all.14132

Rodrigo, 2011, Efficacy of fluticasone furoate nasal spray vs. placebo for the treatment of ocular and nasal symptoms of allergic rhinitis: a systematic review, Clin Exp Allergy, 41, 160, 10.1111/j.1365-2222.2010.03654.x

Walford, 2014, Increased ILC2s in the eosinophilic nasal polyp endotype are associated with corticosteroid responsiveness, Clin Immunol, 155, 126, 10.1016/j.clim.2014.09.007

Saatian, 2013, Interleukin-4 and interleukin-13 cause barrier dysfunction in human airway epithelial cells, Tissue Barriers, 1, 10.4161/tisb.24333

Soyka, 2015, The induction of IL-33 in the sinus epithelium and its influence on T-Helper cell responses, PLos One, 10, 10.1371/journal.pone.0123163