Molecular toxicity mechanism of nanosilver

Chen, 2008, Nanosilver: a nanoproduct in medical application, Toxicol Lett, 176, 1, 10.1016/j.toxlet.2007.10.004

Nowack, 2011, 120 years of nanosilver history: implications for policy makers, Environ Sci Technol, 45, 1177, 10.1021/es103316q

Sanford, 2010, State of the science literature review: everything nanosilver and more, 1

Schluesener, 2013, Nanosilver: application and novel aspects of toxicology, Arch Toxicol, 87, 569, 10.1007/s00204-012-1007-z

2013

Luoma, 2008, Silver nanotechnologies and the environment: old problems or new challenges, 1

Levard, 2012, Environmental transformations of silver nanoparticles: impact on stability and toxicity, Environ Sci Technol, 46, 6900, 10.1021/es2037405

Liu, 2012, Chemical transformations of nanosilver in biological environments, ACS Nano, 6, 9887, 10.1021/nn303449n

Reidy, 2013, Mechanisms of silver nanoparticle release, transformation and toxicity: a critical review of current knowledge and recommendations for future studies and applications, Materials, 6, 2295, 10.3390/ma6062295

Sharma, 2013, Stability and toxicity of silver nanoparticles in aquatic environment: a review, vol. 1124, 165

Stevenson, 2013, Environmental feedbacks and engineered nanoparticles: mitigation of silver nanoparticle toxicity to Chlamydomonas reinhardtii by algal-produced organic compounds, PLoS One, 8, e74456, 10.1371/journal.pone.0074456

Unrine, 2012, Biotic and abiotic interactions in aquatic microcosms determine fate and toxicity of Ag nanoparticles. Part 1. Aggregation and dissolution, Environ Sci Technol, 46, 6915, 10.1021/es204682q

Yu, 2013, Silver nanoparticles in the environment, Environ Sci Proc Impacts, 15, 78, 10.1039/C2EM30595J

Wijnhoven, 2009, Nano-silver – a review of available data and knowledge gaps in human and environmental risk assessment, Nanotoxicity, 3, 109, 10.1080/17435390902725914

Wadhera, 2005, Systemic argyria associated with ingestion of colloidal silver, Dermatol Online J, 11, 12, 10.5070/D30832G6D3

Lansdown, 2004, A review of the use of silver in wound care: facts and fallacies, Br J Nurs, 13, 6, 10.12968/bjon.2004.13.Sup1.12535

Awasthi, 2013, Silver nanoparticle induced cytotoxicity, oxidative stress, and DNA damage in CHO cells, J Nanopart Res, 15, 1898, 10.1007/s11051-013-1898-5

Baruwati, 2013, “Green” synthesized and coated nanosilver alters the membrane permeability of barrier (intestinal, brain endothelial) cells and stimulates oxidative stress pathways in neurons, ACS Sustainable Chem Eng, 1, 753, 10.1021/sc400024a

Haase, 2012, Effects of silver nanoparticles on primary mixed neural cell cultures: uptake, oxidative stress and acute calcium responses, Toxicol Sci, 126, 457, 10.1093/toxsci/kfs003

He, 2012, Silver nanoparticle–algae interactions: oxidative dissolution, reactive oxygen species generation and synergistic toxic effects, Environ Sci Technol, 46, 8731, 10.1021/es300588a

Hunt, 2013, Nanosilver suppresses growth and induces oxidative damage to DNA in Caenorhabditis elegans, J Appl Toxicol, 33, 1131, 10.1002/jat.2872

Lim, 2012, Oxidative stress-related PMK-1 P38 MAPK activation as a mechanism for toxicity of silver nanoparticles to reproduction in the nematode Caenorhabditis elegans, Environ Toxicol Chem, 31, 585, 10.1002/etc.1706

Roh, 2012, Involvement of Caenorhabditis elegans MAPK signaling pathways in oxidative stress response induced by silver nanoparticles exposure, Toxicol Res, 28, 19, 10.5487/TR.2012.28.1.019

van Aerle, 2013, Molecular mechanisms of toxicity of silver nanoparticles in zebrafish embryos, Environ Sci Technol, 47, 8005, 10.1021/es401758d

Wu, 2013, Silver nanoparticles cause oxidative damage and histological changes in medaka (Oryzias latipes) after 14 days of exposure, Environ Toxicol Chem, 32, 165, 10.1002/etc.2038

Yang, 2012, Mechanism of silver nanoparticle toxicity is dependent on dissolved silver and surface coating in Caenorhabditis elegans, Environ Sci Technol, 46, 1119, 10.1021/es202417t

Johnston, 2010, A review of the in vivo and in vitro toxicity of silver and gold particulates: particle attributes and biological mechanisms responsible for the observed toxicity, Crit Rev Toxicol, 40, 328, 10.3109/10408440903453074

Kruszewski, 2011, Toxicity of silver nanomaterials in higher eukaryotes, 179, 10.1016/B978-0-444-53864-2.00005-0

Lynch, 2008, Protein–nanoparticle interactions (review), Nanotoday, 3, 40, 10.1016/S1748-0132(08)70014-8

Bone, 2012, Biotic and abiotic interactions in aquatic microcosms determine fate and toxicity of Ag nanoparticles: part 2 – toxicity and Ag speciation, Environ Sci Technol, 46, 6925, 10.1021/es204683m

Calder, 2012, Soil components mitigate the antimicrobial effects of silver nanoparticles towards a beneficial soil bacterium, Pseudomonas chlororaphis O6, Sci Total Environ, 429, 215, 10.1016/j.scitotenv.2012.04.049

Cheng, 2011, Toxicity reduction of polymer-stabilized silver nanoparticles by sunlight, J Phys Chem C, 115, 4425, 10.1021/jp109789j

Cunningham, 2013, Effect of nanoparticle stabilization and physicochemical properties on exposure outcome: acute toxicity of silver nanoparticle preparations in zebrafish (Danio rerio), Environ Sci Technol, 47, 3883, 10.1021/es303695f

El Badawy, 2011, Surface charge-dependent toxicity of silver nanoparticles, Environ Sci Technol, 45, 283, 10.1021/es1034188

George, 2012, Surface defects on plate-shaped silver nanoparticles contribute to its hazard potential in a fish gill cell line and zebrafish embryos, ACS Nano, 6, 3745, 10.1021/nn204671v

Joshi, 2012, Enhanced resistance to nanoparticle toxicity is conferred by overproduction of extracellular polymeric substances, J Hazard Mat, 241–242, 363, 10.1016/j.jhazmat.2012.09.057

Kim, 2013, Silver nanoparticle toxicity in the embryonic zebrafish is governed by particle dispersion and ionic environment, Nanotechnology, 24, 115101, 10.1088/0957-4484/24/11/115101

Levard, 2013, Effect of chloride on the dissolution rate of silver nanoparticles and toxicity to E. coli, Environ Sci Technol, 47, 5738, 10.1021/es400396f

Newton, 2013, Silver nanoparticle toxicity to Daphnia magna is a function of dissolved silver concentration, Environ Toxicol Chem, 32, 2356, 10.1002/etc.2300

Tyne, 2013, A new medium for Caenorhabditis elegans toxicology and nanotoxicology studies designed to better reflect natural soil solution conditions, Environ Toxicol Chem, 32, 1711, 10.1002/etc.2247

Dale, 2013, Modeling nanosilver transformations in freshwater sediments, Environ Sci Technol, 47, 122920, 10.1021/es402341t

Chae, 2009, Evaluation of the toxic impact of silver nanoparticles on Japanese medaka (Oryzias latipes), Aquat Toxicol, 94, 320, 10.1016/j.aquatox.2009.07.019

Meyer, 2010, Intracellular uptake and associated toxicity of silver nanoparticles in Caenorhabditis elegans, Aquat Toxicol, 100, 140, 10.1016/j.aquatox.2010.07.016

Nair, 2012, Modulation in the mRNA expression of ecdysone receptor gene in aquatic midge, Chironomus riparius upon exposure to nonylphenol and silver nanoparticles, Environ Toxicol Pharmacol, 33, 98, 10.1016/j.etap.2011.09.006

Oukarroum, 2013, Silver nanoparticle toxicity effect on growth and cellular viability of the aquatic plant Lemna gibba, Environ Toxicol Chem, 32, 902, 10.1002/etc.2131

Pokhrel, 2012, Potential impact of low-concentration silver nanoparticles on predator-prey interactions between predatory dragonfly nymphs and Daphnia magna as a prey, Environ Sci Technol, 46, 7755, 10.1021/es204055c

Siller, 2013, Silver nanoparticle toxicity in sea urchin Paracentrotus lividus, Environ Pollut, 178, 498, 10.1016/j.envpol.2013.03.010

Sinko, 2014, Alteration of cholinesterase activity as possible mechanism of silver nanoparticle toxicity, Environ Sci Pollut Res Int, 21, 1391, 10.1007/s11356-013-2016-z

VandeVoort, 2012, Effect of silver nanoparticles on soil denitrification kinetics, Ind Biotech, 8, 358, 10.1089/ind.2012.0026

Yeo, 2008, Effects of nanometer sized silver materials on biological toxicity during zebrafish embryogenesis, Bull Kor Chem Soc, 29, 1179, 10.5012/bkcs.2008.29.6.1179

Egorova, 2010, Biological effects of silver nanoparticles, 221

Liu, 2010, Controlled release of biologically active silver from nanosilver surfaces, ACS Nano, 4, 6903, 10.1021/nn102272n

Volker, 2013, The biological effects and possible modes of action of nanosilver, Rev Environ Contam Toxicol, 223, 81

Li, 2013, Surface-coating-dependent dissolution, aggregation, and reactive oxygen species (ROS) generation of silver nanoparticles under different irradiation conditions, Environ Sci Technol, 47, 10293

Ahamed, 2008, DNA damage response to different surface chemistry of silver nanoparticles in mammalian cells, Toxicol Appl Pharmacol, 233, 404, 10.1016/j.taap.2008.09.015

Bae, 2011, Effect of chemical stabilizers in silver nanoparticle suspensions on nanotoxicity, Bull Kor Chem Soc, 32, 613, 10.5012/bkcs.2011.32.2.613

Bilberg, 2012, In vivo toxicity of silver nanoparticles and silver ions in zebrafish (Danio rerio), J Toxicol, 10.1155/2012/293784

Hedayati, 2012, Comparison of toxicity responses by water exposure to silver nanoparticles and silver salt in common carp (Cyprinus carpio), Global Veterinaria, 8, 179

Shoults-Wilson, 2010, Effect of silver nanoparticle surface coating on bioaccumulation and reproductive toxicity in earthworms (Eisenia fetida), Nanotoxicology, 5, 432, 10.3109/17435390.2010.537382

Silva, 2014, Particle size, surface charge and concentration dependent ecotoxicity of three organo-coated silver nanoparticles: comparison between general linear model-predicted and observed toxicity, Sci Total Environ, 468–469, 968, 10.1016/j.scitotenv.2013.09.006

Lankveld, 2010, The kinetics of the tissue distribution of silver nanoparticles of different sizes, Biomaterials, 31, 8350, 10.1016/j.biomaterials.2010.07.045

Lee, 2007, Silver nanoparticle−oligonucleotide conjugates based on DNA with triple cyclic disulfide moieties, Nano Lett, 7, 2112, 10.1021/nl071108g

Liu, 2010, Ion release kinetics and particle persistence in aqueous nano-silver colloids, Environ Sci Technol, 44, 2169, 10.1021/es9035557

Liu, 2011, Kinetics and mechanisms of nanosilver oxysulfidation, Environ Sci Technol, 45, 7345, 10.1021/es201539s

Mahato, 2011, Study of silver nanoparticle-hemoglobin interaction and composite formation, Colloids Surf B Biointerfaces, 88, 141, 10.1016/j.colsurfb.2011.06.024

McLaughlin, 2012, Effects of natural water chemistry on nanosilver behavior and toxicity to Ceriodaphnia dubia and Pseudokirchneriella subcapitata, Environ Toxicol Chem, 31, 168, 10.1002/etc.720

Choi, 2009, Role of sulfide and ligand strength in controlling nanosilver toxicity, Water Res, 43, 1879, 10.1016/j.watres.2009.01.029

Shi, 2012, Effect of light on toxicity of nanosilver to Tetrahymena pyriformis, Environ Toxicol Chem, 31, 1630, 10.1002/etc.1864

Beer, 2012, Toxicity of silver nanoparticles – nanoparticle or silver ion?, Toxicol Lett, 208, 286, 10.1016/j.toxlet.2011.11.002

van der Zande, 2012, Distribution, elimination, and toxicity of silver nanoparticles and silver ions in rats after 28-day oral exposure, ACS Nano, 6, 7427, 10.1021/nn302649p

AshaRani, 2009, Anti-proliferative activity of silver nanoparticles, BMC Cell Biol, 10, 65, 10.1186/1471-2121-10-65

Asharani, 2008, Toxicity of silver nanoparticles in zebrafish models, Nanotechnology, 19

Braydich-Stolle, 2010, Silver nanoparticles disrupt GDNF/Fyn kinase signaling in spermatogonial stem cells, Toxicol Sci, 116, 577, 10.1093/toxsci/kfq148

Gopinath, 2010, Signaling gene cascade in silver nanoparticle induced apoptosis, Colloids Surf B, 77, 240, 10.1016/j.colsurfb.2010.01.033

He, 2012, Mechanisms of the pH dependent generation of hydroxyl radicals and oxygen induced by Ag nanoparticles, Biomaterials, 33, 7457, 10.1016/j.biomaterials.2012.06.076

Bressan, 2013, Silver nanoparticles and mitochondrial interaction, Int J Dentistry, 2013, 312747, 10.1155/2013/312747

Carlson, 2008, Unique cellular interaction of silver nanoparticles: size-dependent generation of reactive oxygen species, J Phys Chem B, 112, 13608, 10.1021/jp712087m

Chairuangkitti, 2012, Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways, Toxicol In Vitro, 27, 330, 10.1016/j.tiv.2012.08.021

Choi, 2008, Size dependent and reactive oxygen species related nanosilver toxicity to nitrifying bacteria, Environ Sci Technol, 42, 4583, 10.1021/es703238h

Xiu, 2011, Differential effect of common ligands and molecular oxygen on antimicrobial activity of silver nanoparticles versus silver ions, Environ Sci Technol, 45, 9003, 10.1021/es201918f

Zhang, 2013, Photogeneration of reactive oxygen species on uncoated silver, gold, nickel, and silicon nanoparticles and their antibacterial effects, Langmuir, 29, 4647, 10.1021/la400500t

Ahmadi, 2012, Impact of different levels of silver nanoparticles (Ag-NPs) on performance, oxidative enzymes, and blood parameters in broiler chicks, Pakistan Vet J, 32, 325

Cheng, 2013, Revealing silver cytotoxicity using Au nanorods/Ag shell nanostructures: disrupting cell membrane and causing apoptosis through oxidative damage, RSC Adv, 3, 2296, 10.1039/c2ra23131j

Miao, 2010, Intracellular uptake: a possible mechanism for silver engineered nanoparticle toxicity to a freshwater alga Ochromonas danica, PLoS ONE, 5, e15196, 10.1371/journal.pone.0015196

Piao, 2011, Silver nanoparticles induce oxidative cell damage in human liver cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis, Toxicol Lett, 201, 92, 10.1016/j.toxlet.2010.12.010

Banerjee, 2013, Interaction of silver nanoparticles with proteins: a characteristic protein concentration dependent profile of SPR signal, Coll Surf B: Biointerfaces, 111, 71, 10.1016/j.colsurfb.2013.04.052

Park, 2010, Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism, Toxicol In Vitro, 24, 872, 10.1016/j.tiv.2009.12.001

Hsin, 2008, The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells, Toxicol Lett, 179, 130, 10.1016/j.toxlet.2008.04.015

Ahamed, 2010, Silver nanoparticle applications and human health, Clin Chim Acta, 411, 1841, 10.1016/j.cca.2010.08.016

Kaur, 2011, Interaction of silver nanoparticles with plasma proteins, AIP Conf Proc, 1393, 143, 10.1063/1.3653650

Liu, 2009, Evaluation on the toxicity of nanoAg to bovine serum albumin, Sci Total Environ, 407, 4184, 10.1016/j.scitotenv.2009.01.042

Wigginton, 2010, Binding of silver nanoparticles to bacterial proteins depends on surface modifications and inhibits enzymatic activity, Environ Sci Technol, 44, 2163, 10.1021/es903187s

Hou, 2013, Reduction of silver nanoparticle toxicity by sulfide, Adv Mater Lett, 4, 131, 10.5185/amlett.2012.8413

AshaRani, 2009, Cytotoxicity and genotoxicity of silver nanoparticles in human cells, ACS Nano, 3, 279, 10.1021/nn800596w

Khan, 2011, Studies on interaction of colloidal silver nanoparticles (SNPs) with five different bacterial species, Colloids Surf B Biointerfaces, 87, 129, 10.1016/j.colsurfb.2011.05.012

Khan, 2011, Interaction of silver nanoparticles (SNPs) with bacterial extracellular proteins (ECPs) and its adsorption isotherms and kinetics, J Hazard Mater, 192, 299

Ovington, 2004, The truth about silver, Ostomy Wound Manage, 50, 1

Grigor'Eva, 2013, Fine mechanisms of the interaction of silver nanoparticles with the cells of Salmonella typhimurium and Staphylococcus aureus, BioMetals, 26, 479, 10.1007/s10534-013-9633-3

Lu, 2010, Effect of surface coating on the toxicity of silver nanomaterials on human skin keratinocytes, Chem Phys Lett, 487, 92, 10.1016/j.cplett.2010.01.027

Locht, 2011, Metallic silver fragments cause massive tissue loss in the mouse brain, Basic Clin Pharmacol Toxicol, 109, 1, 10.1111/j.1742-7843.2010.00668.x

Yu, 2013, Quantification of the uptake of silver nanoparticles and ions to HepG2 cells, Environ Sci Technol, 47, 3268, 10.1021/es304346p

Zuykov, 2011, Alteration of shell nacre micromorphology in blue mussel Mytilus edulis after exposure to free-ionic silver and silver nanoparticles, Chemosphere, 84, 701, 10.1016/j.chemosphere.2011.03.021

Kruszewski, 2013, Oxidative DNA damage corresponds to the long term survival of human cells treated with silver nanoparticles, Toxicol Lett, 219, 151, 10.1016/j.toxlet.2013.03.006

Monteiro-Riviere, 2013, Protein binding modulates the cellular uptake of silver nanoparticles into human cells: implications for in vitro to in vivo extrapolations?, Toxicol Lett, 220, 286, 10.1016/j.toxlet.2013.04.022

Hussain, 2005, In vitro toxicity of nanoparticles in BRL 3A rat liver cells, Toxicol In Vitro, 19, 975, 10.1016/j.tiv.2005.06.034

Gaiser, 2013, Effects of silver nanoparticles on the liver and hepatocytes in vitro, Toxicol Sci, 131, 537, 10.1093/toxsci/kfs306

Arora, 2009, Interactions of silver nanoparticles with primary mouse fibroblasts and liver cells, Toxicol Appl Pharmacol, 236, 310, 10.1016/j.taap.2009.02.020

Trickler, 2010, Silver nanoparticle induced blood–brain barrier inflammation and increased permeability in primary rat brain microvessel endothelial cells, Toxicol Sci, 118, 160, 10.1093/toxsci/kfq244

Foldbjerg, 2013, Mechanisms of silver nanoparticle toxicity, Arch Basic Appl Med, 1, 5

Daniel, 2013, Toxicity and immunological activity of silver nanoparticles, Appl Clay Sci, 48, 547, 10.1016/j.clay.2010.03.001

Casals, 2010, Time evolution of the nanoparticle protein corona, ACS Nano, 4, 3623, 10.1021/nn901372t

Casals, 2011, Hardening of the nanoparticle-protein corona in metal (Au, Ag) and oxide (Fe3O4, CoO, and CeO2) nanoparticles, Small, 7, 3479, 10.1002/smll.201101511

Chen, 2012, Interaction of lipid vesicle with silver nanoparticle–serum albumin protein corona, Appl Phys Lett, 100, 13703, 10.1063/1.3672035

Gnanadhas, 2013, Interaction of silver nanoparticles with serum proteins affects their antimicrobial activity in vivo, Antimicrob Agents Chemother, 57, 4945, 10.1128/AAC.00152-13

Linse, 2007, Nucleation of protein fibrillation by nanoparticles, Proc Natl Acad Sci U S A, 104, 8691, 10.1073/pnas.0701250104

Minchenko, 2011, Expression of SNF1/AMP-activated protein kinase and casein kinase-1ε in different rat tissues are sensitive markers of in vivo silver nanoparticles action, Materialwissenschaft Werkstofftechnik, 42, 118, 10.1002/mawe.201100742

Piao, 2011, Silver nanoparticles down-regulate Nrf2-mediated 8-oxoguanine DNA glycosylase 1 through inactivation of extracellular regulated kinase and protein kinase B in human Chang liver cells, Toxicol Lett, 207, 143, 10.1016/j.toxlet.2011.09.002

Saptarshi, 2013, Interaction of nanoparticles with proteins: relation to bio-reactivity of the nanoparticle, J Nanobiotech, 11, 26, 10.1186/1477-3155-11-26

Shannahan, 2013, Silver nanoparticle protein corona composition in cell culture media, PLoS One, 8, e74001, 10.1371/journal.pone.0074001

Vigneshwaran, 2007, Silver–protein (core–shell) nanoparticle production using spent mushroom substrate, Langmuir, 23, 7113, 10.1021/la063627p

Wen, 2013, Binding of cytoskeletal proteins with silver nanoparticles, J Nanobiotech, 11, 26

da Silva Paula, 2009, In vitro effect of silver nanoparticles on creatine kinase activity, J Braz Chem Soc, 20, 1556, 10.1590/S0103-50532009000800024

Mariam, 2011, Study of interaction of silver nanoparticles with bovine serum albumin using fluorescence spectroscopy, J Fluoresc, 21, 2193, 10.1007/s10895-011-0922-3

Rahban, 2010, Nanotoxicity and spectroscopy studies of silver nanoparticle: calf thymus DNA and K562 as targets, J Phys Chem C, 114, 5798, 10.1021/jp910656g

Lim, 2012, Enhanced genotoxicity of silver nanoparticles in DNA repair deficient mammalian cells, Front Genet, 3, 1, 10.3389/fgene.2012.00104

Hackenberg, 2011, Silver nanoparticles: evaluation of DNA damage, toxicity and functional impairment in human mesenchymal stem cells, Toxicol Lett, 201, 27, 10.1016/j.toxlet.2010.12.001

Schins, 2007, Genotoxicity of poorly soluble particles, Inhal Toxicol, 19, 189, 10.1080/08958370701496202

He, 2011, Silver nanoparticle–reactive oxygen species interactions: application of a charging-discharging model, J Phys Chem C, 115, 5461, 10.1021/jp111275a

Rani, 2012, Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells, Genome Integrity, 3, 1

Eom, 2010, p38 MAPK activation, DNA damage, cell cycle arrest and apoptosis as mechanisms of toxicity of silver nanoparticles in Jurkat T cells, Environ Sci Technol, 44, 8337, 10.1021/es1020668

Wang, 2008, Challenge in understanding size and shape dependent toxicity of gold nanomaterials in human skin keratinocytes, Chem Phys Lett, 463, 145, 10.1016/j.cplett.2008.08.039

McShan, 2012, DNA damage in human skin keratinocytes caused by multiwalled carbon nanotubes with carboxylate functionalization, Toxicol Ind Health