Molecular targets for chemoprevention: Role in choosing and developing new agents

European Journal of Cancer, Supplement - Tập 5 - Trang 388-390 - 2007
William P. Steward1
1Department of Cancer Studies and Molecular Medicine, University of Leicester, Leicester Royal Infirmary, Leicester, UK

Tài liệu tham khảo

Cuzik, 2003, Overview of the main outcomes in breast-cancer prevention trials, Lancet, 361, 296, 10.1016/S0140-6736(03)12342-2 Thompson, 2003, The influence of finasteride on the development of prostate cancer, N Engl J Med, 349, 215, 10.1056/NEJMoa030660 Beta Carotene Cancer Prevention Study Group, 1994, The Alpha-Tocopheral. The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers, N Engl J Med, 330, 1029, 10.1056/NEJM199404143301501 Sebolt-Leopold, 2004, Targeting the mitogen-activated protein kinase cascade to treat cancer, Nature Revs Cancer, 4, 937, 10.1038/nrc1503 Chen, 1998, Inhibition of the c-jun N-terminal kinase (JNK) signalling pathway by curcumin, Oncogene, 17, 173, 10.1038/sj.onc.1201941 Yu, 2004, The STATs of cancer – new molecular targets come of age, Nature Revs Cancer, 4, 97, 10.1038/nrc1275 Pikarsky, 2004, NF-úB functions as a tumour promoter in inflammation-associated cancer, Nature, 431, 461, 10.1038/nature02924 Diehl, 2002, Cycling to cancer with cyclin D1, Cancer Biol Ther, 3, 226, 10.4161/cbt.72 Bohmann, 1987, Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1, Science, 238, 1386, 10.1126/science.2825349 Dannenberg, 2003, Targeting cycloocygenase-2 in human neoplasia: rationale and promise, Cancer Cell, 4, 431, 10.1016/S1535-6108(03)00310-6