Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas

Springer Science and Business Media LLC - Tập 123 Số 4 - Trang 473-484 - 2012
Marcel Kool1, Andrey Korshunov2, Marc Remke1, David Jones1, Maria Schlanstein1, Paul A. Northcott3, Yoon-Jae Cho4, Jan Köster5, Antoinette Schouten‐van Meeteren6, Dannis G. van Vuurden7, Steven C. Clifford8, Torsten Pietsch9, André O. von Bueren10, Stefan Rutkowski10, Martin G. McCabe11, V. Peter Collins12, L. Magnus Bäcklund13, Christine Haberler14, Franck Bourdeaut15, Olivier Delattre15, François Doz16, David W. Ellison17, Richard J. Gilbertson18, Scott L. Pomeroy19, Michael D. Taylor20, Peter Lichter21, Stefan M. Pfister22
1Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
2Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany
3Arthur and Sonia Labatt Brain Tumour Research Centre, Program in Developmental and Stem Cell Biology, Hospital for Sick Children, University of Toronto, Toronto, Canada
4Stanford University School of Medicine, Department of Neurology and Neurological Sciences, Stanford, USA
5Department of Oncogenomis, Academic Medical Center, Amsterdam, The Netherlands
6Department of Pediatric Oncology, Academic Medical Center, Amsterdam, the Netherlands
7Department of Pediatric Oncology/Hematology, Neuro-Oncology Research Group, Cancer Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
8Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne, UK
9Department of Neuropathology, Bonn University, Bonn, Germany
10Department of Pediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
11Manchester Academic Health Science Centre, Manchester, UK
12Department of Pathology, University of Cambridge, Cambridge, UK
13Department of Oncology-Pathology, Karolinska Institute/Karolinska University Hospital, Stockholm, Sweden
14Department of Neuropathology, Medical University, Vienna, Austria
15Laboratoire de génétique et biologie des cancers, Institut Curie, Paris, France
16Department of Pediatric Oncology, Institut Curie and University Paris Descartes, Sorbonne Paris, France
17Department of Pathology, St Jude Children’s Research Hospital, Memphis, USA
18Department of Developmental Neurobiology, St. Jude Children’s Research Hospital, Memphis, USA
19Department of Neurology, Children’s Hospital Boston, Harvard Medical School, Boston, USA
20Division of Neurosurgery, Hospital for Sick Children, University of Toronto, Toronto, Canada
21Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany
22Department of Pediatric Hematology and Oncology, Heidelberg University Hospital, Heidelberg, Germany

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Springer Science and Business Media LLC

Tập 123 Số 4

473-484

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