Molecular steps in sGC activation

BMC Pharmacology - Tập 7 Số S1 - 2007
Elizabeth M. Boon1, Stephen Cary1, Shirley Huang2, Jonathan A. Winger1, Emily R. Derbyshire2, Mark S. Price2, W. Kaya Erbil1, Michael A. Marletta2,3
1Department of Chemistry, University of California, Berkeley, Berkeley, USA
2Department of Molecular and Cell Biology, University of California, Berkeley, USA
3Lawrence Berkeley National Laboratory, Berkeley, USA

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Tài liệu tham khảo

Iyer LM, Anantharaman V, Aravind L: Ancient conserved domains shared by animal soluble guanylyl cyclases and bacterial signaling proteins. BMC Genomics. 2003, 4: 5-10.1186/1471-2164-4-5.

Karow DS, Pan D, Tran R, Pellicena P, Presley A, Mathies RA, Marletta MA: Spectroscopic characterization of the soluble guanylate cyclase-like heme domains from Vibrio cholerae and Thermoanaerobacter tengcongensis. Biochemistry. 2004, 43: 10203-10211. 10.1021/bi049374l.

Nioche P, Berka V, Vipond J, Minton N, Tsai AL, Raman CS: Femtomolar sensitivity of a NO sensor from Clostridium botulinum. Science. 2004, 306: 1550-1553. 10.1126/science.1103596.

Pellicena P, Karow DS, Boon EM, Marletta MA, Kuriyan J: Crystal structure of an oxygen-binding heme domain related to soluble guanylate cyclases. Proc Natl Acad Sci. 2004, 101: 12854-12859. 10.1073/pnas.0405188101.

Boon EM, Huang SH, Marletta MA: A molecular basis for NO selectivity in soluble guanylate cyclase. Nat Chem Biol. 2005, 1: 53-59. 10.1038/nchembio704.

Gray JM, Karow DS, Lu H, Chang AJ, Chang JS, Ellis RE, Marletta MA, Bargmann CI: Oxygen sensation and social feeding mediated by a C. elegans guanylate cyclase homologue. Nature. 2004, 430: 317-322. 10.1038/nature02714.

Ma X, Sayed N, Beuve A, van den Akker F: NO and CO differentially activate soluble guanylyl cyclase via a heme pivot-bend mechanism. EMBO J. 2007, 26: 578-588. 10.1038/sj.emboj.7601521.

Russwurm M, Koesling D: NO activation of guanylyl cyclase. EMBO J. 2004, 23: 4443-4450. 10.1038/sj.emboj.7600422.

Cary SP, Winger JA, Derbyshire ER, Marletta MA: Nitric oxide signaling: no longer simply on or off. Trends Biochem Sci. 2006, 31: 231-239. 10.1016/j.tibs.2006.02.003.

Cary SP, Winger JA, Marletta MA: Tonic and acute nitric oxide signaling through soluble guanylate cyclase is mediated by nonheme nitric oxide, ATP, and GTP. Proc Natl Acad Sci. 2005, 102: 13064-13069. 10.1073/pnas.0506289102.