Molecular staging of head and neck squamous carcinoma

Beahrs OH, Henson DE, Hutter RVP, Myers MH (eds): Manual for staging of cancer. 3rd ed. Philadelphia: J.B. Lippincott: 27–62, 1988 Robbins KT: Neck dissection classification and TNM staging of head and neck cancer. American Academy of Otolaryngology-Head and Neck Surgery Foundation: 1–29, 1991 Thawley SE, Panje WR: Comprehensive management of head and neck tumors. Philadelphia: W.B. Saunders Company: 780, 1987 Biller HF, Davis WH, Ogura JH: Delayed contralateral cervical metastases with laryngeal and laryngopharyngeal cancers. Laryngoscope 81: 1499, 1971 Ogura JH, Biller HF, Wette R: Elective neck dissection for pharyngeal and laryngeal cancers: an evaluation. Ann Otol Rhinol Laryngol 80: 646, 1971 Brennan JA, Mao L, Hruban RH et al..: Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Eng J Med 332: 429–435, 1995 Sidransky D, Von Eschenbach A, Tsai YC et al.: Identification of p53 gene mutations in bladder cancers and urine samples. Science 252: 706–709, 1991 Sidransky D, Mikkelsen T, Schwechheimer K, Rosenblum ML, Cavanee W, Vogelstein B: Clonal expansion of p53 mutant cells is associated with brain tumour progression. Nature 355: 846–847, 1992 Sidransky D, Tokino T, Hamilton SR et al.: Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors. Science 256: 102–105, 1992 Boyle J, Hakim J, Koch W et al.: The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 53: 4477–4480, 1993 Brennan JA, Boyle JO, Koch WM et al.: Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 332: 712–717, 1995 Thomas S, Brennan J, Martel G et al.: Mutations in the conserved regions of p53 are infrequent in betel-associated oral cancers from Papua New Guinea. Cancer Res 54: 3588–3593, 1994 Koch WM, Patel H, Brennan JA, Boyle JO, Sidransky D: Squamous cell carcinoma of the head and neck in the elderly. Arch Otolaryngol Head Neck Surg 121: 262–265, 1995 Hollstein M, Sidransky D, Vogelstein B, Harris CC: p53 mutations in human cancers. Science 253: 49–53, 1991 Mao L, Hruban RH, Boyle HO, Tockman M, Sidransky D: Detection of oncogene mutations in sputum precedes the diagnosis of lung cancer. Cancer Res 54: 1634–1637, 1994 Nowel PC: The clonal evolution of tumor cell populations. Science 194: 23–28, 1976 Weinberg RA: Tumor Suppressor Genes. Science 254: 1138–1146, 1991 Friedman T: Gene therapy of cancer through restoration of tumor-suppressor functions? Cancer 70: 1810–1817, 1992 Weinberg RA: The integration of molecular genetics into cancer management. Cancer 70: 1653–1658, 1992 Sidransky D, Frost P, Von Eschenbach A, Oyasu R, Preisinger AC, Vogelstein B: Clonal origin of bladder cancer. N Engl J Med 326: 737–740, 1992 Vogelstein B, Kinzler KW: Carcinogens leave fingerprints. Nature 355: 209–210, 1992 Harris CC, Hollstein M: Clinical implications of the p53 tumor-suppressor gene. N Engl J Med 329: 1318–1327, 1993 Hunter T: Cooperation between oncogenes. Cell 64: 249–270, 1991 Fearon ER, Vogelstein B: A genetic model for colorectal tumorigenesis. Cell 61: 759–767, 1990 Peto R, Roe FJ, Lee PN, Levy L, Clack J: Cancer and ageing in mice and man. Br J Cancer 32: 411–426, 1975 Dix D: The role of aging in cancer incidence: an epidemiological study. J Gerontol 44: 10–18, 1989 Puisieux A, Lim S, Groopman J, Ozturk M: Selective targeting of p53 gene mutational hotspots in human cancers by etiologically defined carcinogens. Cancer Res 51: 6185–6189, 1991 Chung KY, Mukhopadhyay T, Kim J et al.: Discordant p53 gene mutations in primary head and neck cancers and corresponding second primary cancers of the upper aerodigestive tract. Cancer Res 53: 1676–1683, 1993 Baker SJ, Preisinger AC, Jessup JM et al.: p53 mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis. Cancer Res 50: 7717–7722, 1990 Buchman GW, Schester DM, Raschtchas A: Rapid and efficent cloning of PCR products using the clone amp system. Focus 14: 41–45, 1992 Gusterson BA, Ramaswamy A, Warren W et al.: Expression of p53 in premalignant and malignant squamous epithelium. Oncogene 6: 1785–1789, 1991 Sakai E, Tsuchida N: Most human squamous cell carcinomas in the oral cavity contain mutated p53 tumor-suppressor genes. Oncogene 7: 927–933, 1992 Melhem MF, Law JC, el-Ashmawy L et al.: Assessment of sensitivity and specificity of immunohistochemical staining of p53 in lung and head and neck cancers. Am J Pathol 146: 1170–1177, 1995 Xu L, Chen YT, Huvos AG, Zlotolow IM et al.: Overexpression of p53 protein in squamous cell carcinomas of the head and neck without apparent gene mutations. Diag Molec Pathol 3: 83–92, 1994 Fisher CJ, Gillett CE, Vojtesek B, Barnes DM, Millis RR: Problems with p53 immunohistochemical staining. Br J Cancer 69: 26–31, 1994 Wynford-Thomas D: p53 in tumour pathology: can we trust immunocytochemistry? J Pathol 166: 329–330, 1992 Brennan JA, Koch WM, Boyle JO et al.: Effect of p53 gene mutation on survival in head and neck squamous carcinoma. Submitted for publication, 1995 Yoo GH, Xu HJ, Brennan JA et al.: Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma. Cancer Res 54: 4603–4606, 1994 Nawroz H, van der Riet P, Koch W, Ruppert JM, Sidransky D: Allelotype of head and neck squamous cell carcinoma. Cancer Res 54: 1152–1155, 1994 Kowalski LP, Magrin J, Waksman G et al.: Supraomohoyoid neck dissection in the treatment of head and neck tumors. Otolaryngol Head Neck Surg 119: 958–963, 1993 Soo KC, Spiro RH, King W, Harvey W, Strong EW: Squamous carcinoma of the gums. Am J Surg 156: 281–285, 1988 Fielding LP, Fenoglio-Preiser CM, Freedman LS: The future of prognostic factors in outcome prediction for patients with cancer. Cancer 70: 2367–2377, 1992 Ghouri AF, Zamora RL, Harvey JE, Spitznagel EL, Sessions DG: Epidermoid carcinoma of the oral cavity and oropharynx: validity of the current AJCC staging system and new statistical tools for the prediction of subclinical neck disease. Otolaryngol Head Neck Surg 108: 225–232, 1993 Snow GB, Annyas AA, van Slooten EA, Bartelink H, Hart AA: Prognostic factors of neck node metastasis. Clin Otolaryngol 7: 185–192, 1982 Boyle JO, Mao L, Brennan JA et al.: Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas. Am J Surg 168: 429–432, 1994 Koch WM, Boule JO, Mao L, Hakim J, Hruban RH, Sidransky D: p53 gene mutations as markers of tumor spread in synchronous oral cancers. Arch Otolaryngol Head Neck Surg 120: 943–947, 1994