Molecular evolution of enzyme structure: Construction of a hybrid hamster/Escherichia coli aspartate transcarbamoylase

Joseph G. Major1, Melinda E. Wales2, John E. Houghton2, Julie A. Maley3, Jeffrey N. Davidson3, James R. Wild2
1Department of Biochemistry and Biophysics, Texas A&M University, College Station 77843.
2Department of Biochemistry and Biophysics, Texas A&M University, College Station, USA
3Department of Microbiology and Immunology, University of Kentucky, Albert B. Chandler Medical Center, Lexington, USA

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