Molecular characterization of the CCR 5 gene in seronegative individuals exposed to human immunodeficiency virus (HIV)

Journal of Clinical Virology - Tập 23 - Trang 161-169 - 2002
M.T. Rugeles1,2, F. Solano2, F.J. Dı́az1, V.I. Bedoya1, P.J. Patiño2
1Immunovirology Group, Laboratorio de Virologia, Facultdad de Medicina, Universidad de Antioquia, A.A. 1226, Medellin, Colombia
2Primary Immunodeficiencies Group, Faculty of Medicine, Universidad de Antioquia, A.A. 1226, Medellin, Colombia

Tài liệu tham khảo

Ainsworth, 1991, Diagnostic single strand conformational polymorphism, (SSCP): a simplified nonradioisotopic method as applied to a tay-sach B-1 variant, Nucleic Acids Res., 19, 405, 10.1093/nar/19.2.405 Berger, 1999, Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease, Annu. Rev. Immunol., 17, 657, 10.1146/annurev.immunol.17.1.657 Cao, 1995, Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection, N. Eng. J. Med., 332, 201, 10.1056/NEJM199501263320401 Carrington, 1997, Novel alleles of the chemokine-receptor gene CCR5, Am. J. Hum. Genet., 61, 1261, 10.1086/301645 Connor, 1997, Change in correceptor use correlates with disease progression in HIV-1 infected individuals, Biochemistry, 185, 621 Cheng-Mayer, 1997, Macrophage tropism of human inmunodeficiency virus type 1 and utilization of the CC-CKR5 coreceptor, J. Virol., 71, 1657, 10.1128/JVI.71.2.1657-1661.1997 Dean, 1996, Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene, Science, 273, 1856, 10.1126/science.273.5283.1856 Edelstein, 1997, Risk of mother-to-infant transmission of HIV-1 is not reduced in CCR5/Δ32ccr5heterozygotes, J. Acquir. Immune. Defic. Syndr. Hum. Retrovirol., 16, 243, 10.1097/00042560-199712010-00004 Fan, 1993, Limitations in the use of SSCP analysis, Mutat. Res., 288, 85, 10.1016/0027-5107(93)90210-7 Goh, 1999, Protections against human immunodeficiency virus type 1 infection in persons within repeated exposure: evidence for T cells immunity in the absence of inherited CCR5 correceptor defects, J. Infect. Dis., 179, 548, 10.1086/314632 Hill, 1996, Natural resistance to HIV?, Nature, 382, 668, 10.1038/382668a0 Hoffman, 1997, CCR5 genotypes in sexually active couples discordant for human inmunodeficiency virus type 1 infection status, J. Infect. Dis., 176, 1093, 10.1086/516519 Huang, 1996, The role of a mutant CCR5 allele in HIV-1 transmission and disease progression, Nat. Med., 2, 1240, 10.1038/nm1196-1240 Kirchhoff, 1995, Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection, N. Eng. J. Med., 332, 228, 10.1056/NEJM199501263320405 Libert, 1998, The delta CCR5 mutation conferring protection against HIV-1 in caucasian populations has a single and recent origin in northeastern Europe, Hum. Mol. Genet., 7, 399, 10.1093/hmg/7.3.399 Martinson, 1997, Global distribution of the ccr5 gene 32-basepair deletion, Nat. Genet., 16, 100, 10.1038/ng0597-100 Mazzoli, 1999, Human immunodeficiency virus (HIV)-specific IgA and HIV neutralizing activity in the serum of exposed seronegative partners of HIV-seropositive persons, J. Infect. Dis., 180, 1, 10.1086/314934 McDermott, 1998, CCR5promoter polymorphism and HIV-1 disease progression, Lancet, 352, 866, 10.1016/S0140-6736(98)04158-0 McNicholl, 1997, Host genes and HIV: the role of the chemokine receptor gene CCR5 and its allele (delta 32), Emerg. Infect. Dis., 3, 261, 10.3201/eid0303.970302 Michael, 1997, The role of viral phenotype and CCr-5 gene defect in HIV-1 transmission and disease progression, Nat. Med., 3, 338, 10.1038/nm0397-338 Moore, 1997, Co-receptors for HIV-1 entry, Curr. Opin. Immunol., 9, 551, 10.1016/S0952-7915(97)80110-0 Mummidi, 1997, The human CC chemokine receptor 5 (CCR5) gene, J. Biol. Chem., 272, 30 662, 30 671, 10.1074/jbc.272.49.30662 Mummidi, 1998, Genealogy of the CCR5 locus and chemokine system gene variants associated with altered rates of HIV-1 disease progression, Nat. Med., 4, 786, 10.1038/nm0798-786 Myers, 1998, Detection of DNA variation, 2, 287 Ostrowski, 1998, Expression of chemokine receptors CXCR4 and CCR5 and HIV-infected and uninfected individuals, J. Immunol., 161, 3195, 10.4049/jimmunol.161.6.3195 Oto, 1993, Optimization of nonradioisotopic single strana conformational polymorphism analysis with a conventional minislab gel electrophoresis apparatus, Annal. Biochem., 213, 19, 10.1006/abio.1993.1379 Pantaleo, 1995, Studies in subjects with long-term nonprogressive human inmunodeficiency virus infection, N. Eng. J. Med., 332, 209, 10.1056/NEJM199501263320402 Pinto, 1997, Immune response to human immunodeficiency virus (HIV) in healthcare workers occupationally exposed to HIV-contaminated blood, Am. J. Med., 102, 21, 10.1016/S0002-9343(97)00056-9 Sambrook, 1989, Isolation of high molecular weight DNA from mammalian cells, 2, 914 Shearer, 1996, Protective immunity against HIV infection: has nature done the experiment for us?, Immunol. Today, 17, 21, 10.1016/0167-5699(96)80564-0 Smith, 1997, Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression, Science, 277, 959, 10.1126/science.277.5328.959 Winkler, 1998, Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant, Science, 279, 389, 10.1126/science.279.5349.389