Molecular basis of epithelial thyroid tumorigenesis

Suárez, 1998, Genetic alterations in epithelial human thyroid tumours, Clin. Endocrinol., 48, 531, 10.1046/j.1365-2265.1998.00443.x Russo, 1995, Activating mutations of the TSH receptor in differentiated thyroid carcinomas, Oncogene, 11, 1907 Russo, 1995, Genetic alterations in thyroid hyperfunctioning adenomas, J. Clin. Endocrinol. Metab, 80, 1347, 10.1210/jc.80.4.1347 Russo, 1996, Thyrotropin receptor gene alterations in thyroid hyperfunctioning adenomas, J. Clin. Endocrinol. Metab., 81, 1548, 10.1210/jc.81.4.1548 Lemoine, 1988, Activated ras oncogenes in human thyroid cancers, Cancer Res., 48, 4459 Lemoine, 1989, High frequence of ras oncogene activation in all stages of human thyroid tumorigenesis, Oncogene, 4, 159 Suárez, 1988, Detection of activated ras oncogenes in human thyroid carcinomas, Oncogene, 2, 403 Suárez, 1990, Presence of mutations in all three ras genes in human thyroid tumors, Oncogene, 5, 565 Lyons, 1990, Two G protein oncogenes in human endocrine tumors, Science, 249, 655, 10.1126/science.2116665 Suárez, 1991, Gsp mutations in human thyroid tumors, Oncogene, 6, 677 Yashimoto, 1992, Role of p53 mutations in endocrine tumorigenesis: mutations detection by polymerase chain reaction-single strand conformation polymorphism, Cancer Res., 52, 5061 Bongarzone, 1989, High frequency of activation of tyrosine kinase oncogenes in human papillary thyroid carcinoma, Oncogene, 4, 1457 Bounacer, 1997, High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation, Oncogene, 15, 1263, 10.1038/sj.onc.1200206 Fusco, 1987, A new oncogene in human papillary thyroid carcinomas and their lymph-nodal metastases, Nature, 328, 170, 10.1038/328170a0 Grieco, 1990, PTC is a novel rearranged form of the ret proto-oncogene and is frequently detected in vivo in human thyroid papillary carcinomas, Cell, 60, 557, 10.1016/0092-8674(90)90659-3 Santoro, 1992, Ret oncogene activation in human thyroid neoplasms is restricted to the papillary cancer subtype, J. Clin. Invest., 89, 1517, 10.1172/JCI115743 Di Renzo, 1992, Overexpression of the c-met/HGF receptor gene in human thyroid carcinomas, Oncogene, 7, 2549 Ivan, 1997, Activated ras and ret oncogenes induce over-expression of c-met (hepatocyte growth factor receptor) in human thyroid epithelial cells, Oncogene, 14, 2417, 10.1038/sj.onc.1201083 Shi, 1991, High rates of ras codon 61 mutations in thyroid tumors in a iodine-deficient area, Cancer Res., 51, 2690 Wright, 1991, Radiation associated and ‘spontaneous' human thyroid carcinomas show different pattern of ras oncogene mutation, Oncogene, 6, 471 Namba, 1990, Point mutations of ras oncogenes are an early event in thyroid tumorigenesis, Mol. Endocrinol., 4, 1474, 10.1210/mend-4-10-1474 Karga, 1991, Ras oncogene mutations in benign and malignant thyroid neoplasms, J. Clin. Endocrinol. Metab., 73, 832, 10.1210/jcem-73-4-832 Saïd, 1994, Oncogenes in human epithelial thyroid tumorigenesis, J. Endocrinol. Inv., 6, 53 Challeton, 1995, Pattern of ras and gsp oncogene mutations in radiation-associated human thyroid tumors, Oncogene, 11, 601 Nikiforov, 1996, Prevalence of mutations of ras and p53 in benign and malignant thyroid tumors from children exposed to radiation after Chernobyl nuclear accident, Oncogene, 13, 687 Wynford-Thomas, 1993, Molecular basis of epithelial tumorigenesis: the thyroid model, Crit. Rev. Oncog., 4, 1 Du Villard, 1995, Role of ras and gsp oncogenes in human epithelial thyroid tumorigenesis, J. Endocrinol. Inv., 18, 124, 10.1007/BF03349719 O'Sullivan, 1991, Activating point mutations of the gsp oncogene in human thyroid adenomas, Mol. Carcinog., 4, 345, 10.1002/mc.2940040503 Parma, 1993, Somatic mutations in the tyrotropin receptor gene cause hyperfunctioning thyroid adenomas, Nature, 365, 649, 10.1038/365649a0 Van Sande, 1995, Somatic and germline mutations of the TSH receptor gene in thyroid diseases, J. Clin. Endocrinol. Metab., 80, 2577, 10.1210/jc.80.9.2577 Michiels, 1994, Oncogenic potential of guanine nucleotide stimulatory factor alpha subunit in thyroid glands of transgenic mice, Proc. Nat. Acad. Sci. USA, 91, 10488, 10.1073/pnas.91.22.10488 Wicker, 1996, Le facteur de croissance des hépatocytes HGF-SF et son récepteur c-Met: Fonctions biologiques et activation oncogénique, Médecine/Sciences, 3, 313, 10.4267/10608/734 Sarasin, 1999, Mechanisms of mutagenesis in mammalian cells: application to human thyroid tumors, C. R. Acad. Sci., 322, 143, 10.1016/S0764-4469(99)80037-7 Bongarzone, 1993, Molecular characterization of a thyroid tumor-specific transforming sequence formed by the fusion of ret tyrosine kinase and the regulatory subunit RIα of cyclic AMP-dependent protein kinase A, Mol. Cell. Biol., 13, 358, 10.1128/MCB.13.1.358 Santoro, 1994, Molecular characterization of RET/PTC3; a novel rearranged version of the RET proto-oncogene in human thyroid papillary carcinoma, Oncogene, 9, 509 Fugazzola, 1996, Molecular and biochemical analysis of RET/PTC4 a novel oncogenic rearrangement between RET and ELE1 genes, in a post-Chernobyl papillary thyroid cancer, Oncogene, 13, 1093 Klugbauer, 1996, A new form of RET rearrangement in thyroid carcinomas of children after the Chernobyl accident, Oncogene, 13, 1099 Ishizaka, 1991, Detection of retTPC/PTC transcripts in thyroid adenomas and adenomatous goiter by an RT-PCR method, Oncogene, 6, 1667 Fugazzola, 1995, Oncogenic rearrangements of the RET proto-oncogene in papillary thyroid carcinomas from children exposed to the Chernobyl nuclear accident, Cancer Res., 55, 5617 Klugbauer, 1995, High prevalence of RET rearrangement in thyroid tumors of children from Belarus after the Chernobyl reactor accident, Oncogene, 11, 2459 Nikiforov, 1997, Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children, Cancer Res., 57, 1690 Bongarzone, 1996, Age-related activation of the tyrosine kinase receptor protooncogenes RET and NTRK1 in papillary thyroid carcinoma, J. Clin. Endocrinol. Metab., 81, 2006, 10.1210/jc.81.5.2006 Fogelfeld, 1996, p53 gene mutations in radiation-induced thyroid cancer, J. Clin. Endocrinol. Metab., 81, 3039, 10.1210/jc.81.8.3039