Molecular Weight and Proposed Structure of the Angelica sinensis Polysaccharide‐iron Complex

Chinese Journal of Chemistry - Tập 26 Số 6 - Trang 1068-1074 - 2008
Kaiping Wang, Z. Chen1, Yu Zhang1, Peipei Wang1, J.F. Wang1, Dai Liquan1
1Faculty of Pharmacy, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China

Tóm tắt

AbstractThe molecular weight and the proposed structure of the Angelica sinensis polysaccharide‐iron complex (APIC) were studied. Fourier transform infrared spectroscopy, X‐ray powder diffraction, differential scanning calorimetry, transmission electron microscopy, electron paramagnetic resonance, thermogravimetric analysis, atomic force microscopy, and gel filtration chromatography were used to characterize APIC, which is a macromolecule complex composed of Angelica sinensis polysaccharide (ASP) and iron. The structure of APIC was proposed to be a polynuclear ferrihydrite core chelated firmly by an encircling framework of ASP chains, forming a core molecule, which is surrounded by a removable outer protective sheath of colloidal ASP. And the molecular formula of APIC was proposed to be {[(Fe2O3·2.2H2O)1043(ASP)32](ASP)12}, with MW=270000 Da.

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Thông tin
Thông tin xuất bản

Chinese Journal of Chemistry

Tập 26 Số 6

1068-1074

Thông tin tác giả