Molecular Assessment of C4d-Positive Renal Transplant Biopsies Without Evidence of Rejection

Kidney International Reports - Tập 4 - Trang 148-158 - 2019
Katherine M. Dominy1, Michelle Willicombe1, Tariq Al Johani2, Hannah Beckwith3, Dawn Goodall3, Paul Brookes3, H. Terence Cook1,3, Tom Cairns3, Adam McLean3, Candice Roufosse1,3
1Centre for Inflammatory Diseases, Imperial College, London, UK
2King Saud University, Riyadh, Saudi Arabia
3Imperial College Healthcare NHS Trust, London, UK

Tài liệu tham khảo

Feucht, 1991, Vascular deposition of complement-split products in kidney allografts with cell-mediated rejection, Clin Exp Immunol, 86, 464, 10.1111/j.1365-2249.1991.tb02954.x Feucht, 1993, Capillary deposition of C4d complement fragment and early renal graft loss, Kidney Int, 43, 1333, 10.1038/ki.1993.187 Racusen, 2004, Banff 2003 meeting report: new diagnostic insights and standards, Am J Transplant, 4, 1562, 10.1111/j.1600-6143.2004.00585.x Racusen, 2003, Antibody-mediated rejection criteria—an addition to the Banff 97 classification of renal allograft rejection, Am J Transplant, 3, 708, 10.1034/j.1600-6143.2003.00072.x Solez, 2007, Banff '05 Meeting Report: differential diagnosis of chronic allograft injury and elimination of chronic allograft nephropathy ('CAN'), Am J Transplant, 7, 518, 10.1111/j.1600-6143.2006.01688.x Feucht, 1996, The humoral immune response towards HLA class II determinants in renal transplantation, Kidney Int, 50, 1464, 10.1038/ki.1996.460 Murata, 2009, Mechanisms of complement activation, C4d deposition, and their contribution to the pathogenesis of antibody-mediated rejection, Transplant Rev (Orlando), 23, 139, 10.1016/j.trre.2009.02.005 Haas, 2014, Banff 2013 meeting report: inclusion of c4d-negative antibody-mediated rejection and antibody-associated arterial lesions, Am J Transplant, 14, 272, 10.1111/ajt.12590 Sis, 2010, Endothelial transcripts uncover a previously unknown phenotype: C4d-negative antibody-mediated rejection, Curr Opin Organ Transplant, 15, 42, 10.1097/MOT.0b013e3283352a50 Hidalgo, 2010, NK cell transcripts and NK cells in kidney biopsies from patients with donor-specific antibodies: evidence for NK cell involvement in antibody-mediated rejection, Am J Transplant, 10, 1812, 10.1111/j.1600-6143.2010.03201.x Sis, 2009, Endothelial gene expression in kidney transplants with alloantibody indicates antibody-mediated damage despite lack of C4d staining, Am J Transplant, 9, 2312, 10.1111/j.1600-6143.2009.02761.x Park, 2003, Accommodation in ABO-incompatible kidney allografts, a novel mechanism of self-protection against antibody-mediated injury, Am J Transplant, 3, 952, 10.1034/j.1600-6143.2003.00179.x Haas, 2010, The significance of C4d staining with minimal histologic abnormalities, Curr Opin Organ Transplant, 15, 21, 10.1097/MOT.0b013e3283342ebd Haas, 2006, C4d and C3d staining in biopsies of ABO- and HLA-incompatible renal allografts: correlation with histologic findings, Am J Transplant, 6, 1829, 10.1111/j.1600-6143.2006.01356.x Baldwin, 2003, Complement in transplant rejection: diagnostic and mechanistic considerations, Springer Semin Immunopathol, 25, 181, 10.1007/s00281-003-0133-3 Loupy, 2017, The Banff 2015 Kidney Meeting Report: current challenges in rejection classification and prospects for adopting molecular pathology, Am J Transplant, 17, 28, 10.1111/ajt.14107 Haas, 2018, The Banff 2017 Kidney Meeting Report: revised diagnostic criteria for chronic active T cell-mediated rejection, antibody-mediated rejection, and prospects for integrative endpoints for next-generation clinical trials, Am J Transplant, 18, 293, 10.1111/ajt.14625 Sigdel, 2018, Targeted transcriptional profiling of kidney transplant biopsies, Kidney Int Rep, 3, 722, 10.1016/j.ekir.2018.01.014 Sellares, 2013, Molecular diagnosis of antibody-mediated rejection in human kidney transplants, Am J Transplant, 13, 971, 10.1111/ajt.12150 Venner, 2015, The molecular landscape of antibody-mediated kidney transplant rejection: evidence for NK involvement through CD16a Fc receptors, Am J Transplant, 15, 1336, 10.1111/ajt.13115 Halloran, 2016, Molecular assessment of disease states in kidney transplant biopsy samples, Nat Rev Nephrol, 12, 534, 10.1038/nrneph.2016.85 Halloran, 2010, The molecular phenotype of kidney transplants, Am J Transplant, 10, 2215, 10.1111/j.1600-6143.2010.03267.x Halloran, 2013, Microarray diagnosis of antibody-mediated rejection in kidney transplant biopsies: an international prospective study (INTERCOM), Am J Transplant, 13, 2865, 10.1111/ajt.12465 Dominy, 2015, Use of quantitative real time polymerase chain reaction to assess gene transcripts associated with antibody-mediated rejection of kidney transplants, Transplantation, 99, 1981, 10.1097/TP.0000000000000621 Kikic, 2015, Capillary C4d and kidney allograft outcome in relation to morphologic lesions suggestive of antibody-mediated rejection, Clin J Am Soc Nephrol, 10, 1435, 10.2215/CJN.09901014 Mauiyyedi, 2002, Acute humoral rejection in kidney transplantation: II. Morphology, immunopathology, and pathologic classification, J Am Soc Nephrol, 13, 779, 10.1681/ASN.V133779 Djamali, 2013, Increased C4d in post-reperfusion biopsies and increased donor specific antibodies at one-week post transplant are risk factors for acute rejection in mild to moderately sensitized kidney transplant recipients, Kidney Int, 83, 1185, 10.1038/ki.2013.44 Haas, 2002, C4d staining of perioperative renal transplant biopsies, Transplantation, 74, 711, 10.1097/00007890-200209150-00021 Nickeleit, 2002, Detection of the complement degradation product C4d in renal allografts: diagnostic and therapeutic implications, J Am Soc Nephrol, 13, 242, 10.1681/ASN.V131242 Dickenmann, 2006, The fate of C4d positive kidney allografts lacking histological signs of acute rejection, Clin Nephrol, 65, 173, 10.5414/CNP65173 Regele, 2002, Capillary deposition of complement split product C4d in renal allografts is associated with basement membrane injury in peritubular and glomerular capillaries: a contribution of humoral immunity to chronic allograft rejection, J Am Soc Nephrol, 13, 2371, 10.1097/01.ASN.0000025780.03790.0F Mengel, 2005, Incidence of C4d stain in protocol biopsies from renal allografts: results from a multicenter trial, Am J Transplant, 5, 1050, 10.1111/j.1600-6143.2005.00788.x Koo, 2004, C4d deposition in early renal allograft protocol biopsies, Transplantation, 78, 398, 10.1097/01.TP.0000128328.68106.54 Wasowska, 2010, Mechanisms involved in antibody- and complement-mediated allograft rejection, Immunol Res, 47, 25, 10.1007/s12026-009-8136-3 Ollert, 1994, Antibody-mediated complement activation on nucleated cells. A quantitative analysis of the individual reaction steps, J Immunol, 153, 2213, 10.4049/jimmunol.153.5.2213 Nishi, 2004, Pathological study on the relationship between C4d, CD59 and C5b-9 in acute renal allograft rejection, Clin Transplant, 18, 18, 10.1111/j.1399-0012.2004.00242 Sapir-Pichhadze, 2015, A systematic review of the role of C4d in the diagnosis of acute antibody-mediated rejection, Kidney Int, 87, 182, 10.1038/ki.2014.166 Brocker, 2013, Beyond C4d: the ultrastructural appearances of endothelium in ABO-incompatible renal allografts, Nephrol Dial Transplant, 28, 3101, 10.1093/ndt/gft373 de Kort, 2015, The role of electron microscopy in renal allograft biopsy evaluation, Curr Opin Organ Transplant, 20, 333, 10.1097/MOT.0000000000000183