Modulation of the innate immune response by human cytomegalovirus
Tài liệu tham khảo
Abate, 2004, Major human cytomegalovirus structural protein pp65 (ppUL83) prevents interferon response factor 3 activation in the interferon response, J. Virol., 78, 10995, 10.1128/JVI.78.20.10995-11006.2004
Adler, 2011, Human cytomegalovirus immediate-early gene expression is restricted by the nuclear domain 10 component Sp100, J. Gen. Virol., 92, 1532, 10.1099/vir.0.030981-0
Ahmed, 2011, Antiviral treatment of cytomegalovirus infection, Infect. Disord. Drug Targets, 11, 475, 10.2174/187152611797636640
Ahn, 1997, The major immediate-early proteins IE1 and IE2 of human cytomegalovirus colocalize with and disrupt PML-associated nuclear bodies at very early times in infected permissive cells, J. Virol., 71, 4599, 10.1128/jvi.71.6.4599-4613.1997
Albrecht, 2005, The HIN domain of IFI-200 proteins consists of two OB folds, Biochem. Biophys. Res. Commun., 327, 679, 10.1016/j.bbrc.2004.12.056
Almine, 2017, IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes, Nat. Commun., 8, 14392, 10.1038/ncomms14392
Ashley, 2017, Nuclear domain 10 components upregulated via interferon during human cytomegalovirus infection potently regulate viral infection, J. Gen. Virol., 98, 1795, 10.1099/jgv.0.000858
Barbalat, 2009, Toll-like receptor 2 on inflammatory monocytes induces type I interferon in response to viral but not bacterial ligands, Nat. Immunol., 10, 1200, 10.1038/ni.1792
Bawadekar, 2015, The extracellular IFI16 protein propagates inflammation in endothelial cells via p38 MAPK and NF-κB p65 activation, J. Interferon Cytokine Res. Off. J. Int. Soc. Interferon Cytokine Res., 35, 441, 10.1089/jir.2014.0168
Bhat, 2014, Recognition of cytosolic DNA by cGAS and other STING-dependent sensors, Eur. J. Immunol., 44, 634, 10.1002/eji.201344127
Bieniasz, 2003, Restriction factors: a defense against retroviral infection, Trends Microbiol., 11, 286, 10.1016/S0966-842X(03)00123-9
Biolatti, 2016, Regulatory interaction between the cellular restriction factor IFI16 and viral pp65 (pUL83) modulates viral gene expression and IFI16 protein stability, J. Virol., 90, 8238, 10.1128/JVI.00923-16
Biolatti, 2018, Human cytomegalovirus tegument protein pp65 (pUL83) Dampens type I interferon production by inactivating the DNA sensor cGAS without affecting STING, J. Virol., 92, 10.1128/JVI.01774-17
Blanco-Melo, 2012, Intrinsic cellular defenses against human immunodeficiency viruses, Immunity, 37, 399, 10.1016/j.immuni.2012.08.013
Boehme, 2006, Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells, J. Immunol. Baltim. Md, 1950, 7094
Bossaller, 2012, Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-8 in an RIP3-independent manner, J. Immunol. Baltim. Md, 1950, 5508
Brinkmann, 2015, Cytomegalovirus immune evasion of myeloid lineage cells, Med. Microbiol. Immunol. (Berl.), 204, 367, 10.1007/s00430-015-0403-4
Britt, 2017, Congenital human cytomegalovirus infection and the enigma of maternal immunity, J. Virol., 91, 10.1128/JVI.02392-16
Browne, 2003, Human cytomegalovirus UL83-coded pp65 virion protein inhibits antiviral gene expression in infected cells, Proc. Natl. Acad. Sci. U. S. A., 100, 11439, 10.1073/pnas.1534570100
Brubaker, 2015, Innate immune pattern recognition: a cell biological perspective, Annu. Rev. Immunol., 33, 257, 10.1146/annurev-immunol-032414-112240
Burdette, 2013, STING and the innate immune response to nucleic acids in the cytosol, Nat. Immunol., 14, 19, 10.1038/ni.2491
Cannon, 2010, Review of cytomegalovirus seroprevalence and demographic characteristics associated with infection, Rev. Med. Virol., 20, 202, 10.1002/rmv.655
Cantrell, 2005, Interaction between the human cytomegalovirus UL82 gene product (pp71) and hDaxx regulates immediate-early gene expression and viral replication, J. Virol., 79, 7792, 10.1128/JVI.79.12.7792-7802.2005
Carvalho, 2009, Polymorphisms in Toll-like receptor genes and susceptibility to infections in allogeneic stem cell transplantation, Exp. Hematol., 37, 1022, 10.1016/j.exphem.2009.06.004
Chen, 2015, Response of host inflammasomes to viral infection, Trends Microbiol., 23, 55, 10.1016/j.tim.2014.09.007
Chen, 2016, Regulation and function of the cGAS-STING pathway of cytosolic DNA sensing, Nat. Immunol., 17, 1142, 10.1038/ni.3558
Chin, 2001, Viperin (cig5), an IFN-inducible antiviral protein directly induced by human cytomegalovirus, Proc. Natl. Acad. Sci. U. S. A., 98, 15125, 10.1073/pnas.011593298
Choi, 2018, Human cytomegalovirus-encoded US9 targets MAVS and STING signaling to evade type I interferon immune responses, Nat. Commun., 9, 125, 10.1038/s41467-017-02624-8
Christensen, 2017, Viral evasion of DNA-stimulated innate immune responses, Cell. Mol. Immunol., 14, 4, 10.1038/cmi.2016.06
Compton, 2003, Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2, J. Virol., 77, 4588, 10.1128/JVI.77.8.4588-4596.2003
Cosme, 2011, Functional interaction of nuclear domain 10 and its components with cytomegalovirus after infections: cross-species host cells versus native cells, PloS One, 6, 10.1371/journal.pone.0019187
Cristea, 2010, Human cytomegalovirus pUL83 stimulates activity of the viral immediate-early promoter through its interaction with the cellular IFI16 protein, J. Virol., 84, 7803, 10.1128/JVI.00139-10
Dambuza, 2015, C-type lectins in immunity: recent developments, Curr. Opin. Immunol., 32, 21, 10.1016/j.coi.2014.12.002
DeFilippis, 2006, Interferon regulatory factor 3 is necessary for induction of antiviral genes during human cytomegalovirus infection, J. Virol., 80, 1032, 10.1128/JVI.80.2.1032-1037.2006
DeFilippis, 2010, Human cytomegalovirus induces the interferon response via the DNA sensor ZBP1, J. Virol., 84, 585, 10.1128/JVI.01748-09
Dell’Oste, 2014, Innate nuclear sensor IFI16 translocates into the cytoplasm during the early stage of in vitro human cytomegalovirus infection and is entrapped in the egressing virions during the late stage, J. Virol., 88, 6970, 10.1128/JVI.00384-14
Dell’Oste, 2015, The interferon-inducible DNA-sensor protein IFI16: a key player in the antiviral response, New Microbiol., 38, 5
Diner, 2016, Viral DNA sensors IFI16 and cyclic GMP-AMP synthase possess distinct functions in regulating viral gene expression, immune defenses, and apoptotic responses during herpesvirus infection, mBio, 7, 10.1128/mBio.01553-16
Dobbs, 2015, STING activation by translocation from the ER is associated with infection and autoinflammatory disease, Cell Host Microbe, 18, 157, 10.1016/j.chom.2015.07.001
Everett, 2001, DNA viruses and viral proteins that interact with PML nuclear bodies, Oncogene, 20, 7266, 10.1038/sj.onc.1204759
Everett, 2006, Interactions between DNA viruses, ND10 and the DNA damage response, Cell. Microbiol., 8, 365, 10.1111/j.1462-5822.2005.00677.x
Fan, 2016, Role of nucleotide-binding oligomerization domain 1 (NOD1) and its variants in human cytomegalovirus control in vitro and in vivo, Proc. Natl. Acad. Sci. U. S. A., 113, E7818, 10.1073/pnas.1611711113
Fu, 2017, Human cytomegalovirus tegument protein UL82 inhibits STING-mediated signaling to evade antiviral immunity, Cell Host Microbe, 21, 231, 10.1016/j.chom.2017.01.001
Gao, 2013, Structure-function analysis of STING activation by c[G(2’,5’)pA(3’,5’)p] and targeting by antiviral DMXAA, Cell, 154, 748, 10.1016/j.cell.2013.07.023
Gariano, 2012, The intracellular DNA sensor IFI16 gene acts as restriction factor for human cytomegalovirus replication, PLoS Pathog., 8, 10.1371/journal.ppat.1002498
Garlanda, 2013, The interleukin-1 family: back to the future, Immunity, 39, 1003, 10.1016/j.immuni.2013.11.010
Glass, 2013, Components of promyelocytic leukemia nuclear bodies (ND10) act cooperatively to repress herpesvirus infection, J. Virol., 87, 2174, 10.1128/JVI.02950-12
Gray, 2016, The AIM2-like receptors are dispensable for the interferon response to intracellular DNA, Immunity, 45, 255, 10.1016/j.immuni.2016.06.015
Griffiths, 2015, The pathogenesis of human cytomegalovirus, J. Pathol., 235, 288, 10.1002/path.4437
Gringhuis, 2012, Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome, Nat. Immunol., 13, 246, 10.1038/ni.2222
Guo, 2015, Inflammasomes: mechanism of action, role in disease, and therapeutics, Nat. Med., 21, 677, 10.1038/nm.3893
Gurung, 2015, Novel roles for caspase-8 in IL-1β and inflammasome regulation, Am. J. Pathol., 185, 17, 10.1016/j.ajpath.2014.08.025
Harris, 2015, APOBECs and virus restriction, Virology, 479–480, 131, 10.1016/j.virol.2015.03.012
Hoebe, 2003, Identification of Lps2 as a key transducer of MyD88-independent TIR signalling, Nature, 424, 743, 10.1038/nature01889
Hoffmann, 2015, Interferons and viruses: an evolutionary arms race of molecular interactions, Trends Immunol., 36, 124, 10.1016/j.it.2015.01.004
Hofmann, 2002, Functional interaction between the pp71 protein of human cytomegalovirus and the PML-interacting protein human Daxx, J. Virol., 76, 5769, 10.1128/JVI.76.11.5769-5783.2002
Hotter, 2018, Interferons and beyond: Induction of antiretroviral restriction factors, J. Leukoc. Biol., 103, 465, 10.1002/JLB.3MR0717-307R
Huang, 2017, Human cytomegalovirus triggers the assembly of AIM2 inflammasome in THP-1-derived macrophages, J. Med. Virol., 89, 2188, 10.1002/jmv.24846
Huang, 2017, Interaction between HCMV pUL83 and human AIM2 disrupts the activation of the AIM2 inflammasome, Virol. J., 14, 34, 10.1186/s12985-016-0673-5
Iversen, 2009, A proviral role for CpG in cytomegalovirus infection, J. Immunol. Baltim. Md, 1950, 5672
Jakobsen, 2015, Innate immune sensing of HIV-1 infection. Curr. Opin, HIV AIDS, 10, 96
James, 2016, Advances in the prevention and treatment of congenital cytomegalovirus infection, Curr. Opin. Pediatr., 28, 81, 10.1097/MOP.0000000000000305
Jin, 2012, Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor, Immunity, 36, 561, 10.1016/j.immuni.2012.02.014
Jønsson, 2017, IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP, Nat. Commun., 8, 14391, 10.1038/ncomms14391
Juckem, 2008, Differential initiation of innate immune responses induced by human cytomegalovirus entry into fibroblast cells, J. Immunol. Baltim. Md, 1950, 4965
Kanneganti, 2010, Central roles of NLRs and inflammasomes in viral infection, Nat. Rev. Immunol., 10, 688, 10.1038/nri2851
Kapoor, 2014, Activation of nucleotide oligomerization domain 2 (NOD2) by human cytomegalovirus initiates innate immune responses and restricts virus replication, PloS One, 9, 10.1371/journal.pone.0092704
Kapoor, 2016, Bacterial muramyl dipeptide (MDP) restricts human cytomegalovirus replication via an IFN-β-dependent pathway, Sci. Rep., 6, 20295, 10.1038/srep20295
Kijpittayarit, 2007, Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation, Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am., 44, 1315, 10.1086/514339
Kim, 2016, NOD-like receptors in infection, immunity, and diseases, Yonsei Med. J., 57, 5, 10.3349/ymj.2016.57.1.5
Kim, 2017, Human cytomegalovirus IE2 86 kDa protein induces STING degradation and inhibits cGAMP-mediated IFN-β induction, Front. Microbiol., 8, 1854, 10.3389/fmicb.2017.01854
Knisbacher, 2016, DNA editing by APOBECs: a genomic preserver and transformer, Trends Genet. TIG, 32, 16, 10.1016/j.tig.2015.10.005
Komatsu, 2014, Resistance of human cytomegalovirus to ganciclovir/valganciclovir: a comprehensive review of putative resistance pathways, Antiviral Res., 101, 12, 10.1016/j.antiviral.2013.10.011
Korioth, 1996, The nuclear domain 10 (ND10) is disrupted by the human cytomegalovirus gene product IE1, Exp. Cell Res., 229, 155, 10.1006/excr.1996.0353
Kuenzel, 2010, The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses, J. Immunol. Baltim. Md, 1950, 1990
Landais, 2015, Human cytomegalovirus miR-UL112-3p targets TLR2 and modulates the TLR2/IRAK1/NFκB signaling pathway, PLoS Pathog., 11, 10.1371/journal.ppat.1004881
Landolfo, 2016, Intrinsic host restriction factors of human cytomegalovirus replication and mechanisms of viral escape, World J. Virol., 5, 87, 10.5501/wjv.v5.i3.87
Lee, 2004, Ability of the human cytomegalovirus IE1 protein to modulate sumoylation of PML correlates with its functional activities in transcriptional regulation and infectivity in cultured fibroblast cells, J. Virol., 78, 6527, 10.1128/JVI.78.12.6527-6542.2004
Li, 2013, Human cytomegalovirus tegument protein pUL83 inhibits IFI16-mediated DNA sensing for immune evasion, Cell Host Microbe, 14, 591, 10.1016/j.chom.2013.10.007
Lindsay, 2008, PML NBs (ND10) and Daxx: from nuclear structure to protein function, Front. Biosci. J. Virtual Libr., 13, 7132, 10.2741/3216
Lio, 2016, cGAS-STING signaling regulates initial innate control of cytomegalovirus infection, J. Virol., 90, 7789, 10.1128/JVI.01040-16
Liu, 2015, Phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF induces IRF3 activation, Science, 347, 10.1126/science.aaa2630
Loo, 2011, Immune signaling by RIG-I-like receptors, Immunity, 34, 680, 10.1016/j.immuni.2011.05.003
Lopušná, 2013, Interferons lambda, new cytokines with antiviral activity, Acta Virol., 57, 171, 10.4149/av_2013_02_171
Luecke, 2015, Innate recognition of alphaherpesvirus DNA, Adv. Virus Res., 92, 63, 10.1016/bs.aivir.2014.11.003
Lukashchuk, 2008, Human cytomegalovirus protein pp71 displaces the chromatin-associated factor ATRX from nuclear domain 10 at early stages of infection, J. Virol., 82, 12543, 10.1128/JVI.01215-08
Lupfer, 2015, Inflammasome control of viral infection, Curr. Opin. Virol., 12, 38, 10.1016/j.coviro.2015.02.007
Lupfer, 2015, Inflammasome control of viral infection, Curr. Opin. Virol., 12, 38, 10.1016/j.coviro.2015.02.007
Marshall, 2009, Multifaceted evasion of the interferon response by cytomegalovirus, J. Interferon Cytokine Res. Off. J. Int. Soc. Interferon Cytokine Res., 29, 609, 10.1089/jir.2009.0064
Martinon, 2002, The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta, Mol. Cell, 10, 417, 10.1016/S1097-2765(02)00599-3
Maul, 1993, Modification of discrete nuclear domains induced by herpes simplex virus type 1 immediate early gene 1 product (ICP0), J. Gen. Virol., 74, 2679, 10.1099/0022-1317-74-12-2679
Miller, 1993, Purification and characterization of active human interleukin-1 beta-converting enzyme from THP.1 monocytic cells, J. Biol. Chem., 268, 18062, 10.1016/S0021-9258(17)46811-6
Mogensen, 2009, Pathogen recognition and inflammatory signaling in innate immune defenses, Clin. Microbiol. Rev., 22, 240, 10.1128/CMR.00046-08
Moriwaki, 2015, A RIPK3-Caspase 8 complex mediates atypical pro-IL-1β processing, J. Immunol. Baltim. Md, 1950, 1938
Morrone, 2015, Assembly-driven activation of the AIM2 foreign-dsDNA sensor provides a polymerization template for downstream ASC, Nat. Commun., 6, 7827, 10.1038/ncomms8827
Nakaya, 2016, In vivo examination of mouse APOBEC3- and human APOBEC3A- and APOBEC3G-mediated restriction of parvovirus and herpesvirus infection in mouse models, J. Virol., 90, 8005, 10.1128/JVI.00973-16
Narvaiza, 2009, Deaminase-independent inhibition of parvoviruses by the APOBEC3A cytidine deaminase, PLoS Pathog., 5, 10.1371/journal.ppat.1000439
Navarro, 2016, Expanding role of cytomegalovirus as a human pathogen, J. Med. Virol., 88, 1103, 10.1002/jmv.24450
Negorev, 2001, Cellular proteins localized at and interacting within ND10/PML nuclear bodies/PODs suggest functions of a nuclear depot, Oncogene, 20, 7234, 10.1038/sj.onc.1204764
Neil, 2009, Human immunodeficiency virus, restriction factors, and interferon, J. Interferon Cytokine Res. Off. J. Int. Soc. Interferon Cytokine Res., 29, 569, 10.1089/jir.2009.0077
Noriega, 2012, Diverse immune evasion strategies by human cytomegalovirus, Immunol. Res., 54, 140, 10.1007/s12026-012-8304-8
Novak, 2007, Putative association of a TLR9 promoter polymorphism with atopic eczema, Allergy, 62, 766, 10.1111/j.1398-9995.2007.01358.x
Oliveira-Nascimento, 2012, The role of TLR2 in infection and immunity, Front. Immunol., 3, 79, 10.3389/fimmu.2012.00079
Orzalli, 2014, Cellular sensing of viral DNA and viral evasion mechanisms, Annu. Rev. Microbiol., 68, 477, 10.1146/annurev-micro-091313-103409
Paijo, 2016, cGAS senses human cytomegalovirus and induces type I interferon responses in human monocyte-derived cells, PLoS Pathog., 12, 10.1371/journal.ppat.1005546
Paludan, 2016, Innate antiviral defenses independent of inducible IFNα/β production, Trends Immunol., 37, 588, 10.1016/j.it.2016.06.003
Paludan, 2011, Recognition of herpesviruses by the innate immune system, Nat. Rev. Immunol., 11, 143, 10.1038/nri2937
Pollard, 2013, Interferon-γ and systemic autoimmunity, Discov. Med., 16, 123
Poole, 2015, Sleepless latency of human cytomegalovirus, Med. Microbiol. Immunol. (Berl.), 204, 421, 10.1007/s00430-015-0401-6
Presti, 1998, Interferon gamma regulates acute and latent murine cytomegalovirus infection and chronic disease of the great vessels, J. Exp. Med., 188, 577, 10.1084/jem.188.3.577
Preston, 2006, Role of the cellular protein hDaxx in human cytomegalovirus immediate-early gene expression, J. Gen. Virol., 87, 1113, 10.1099/vir.0.81566-0
Rathinam, 2010, The AIM2 inflammasome is essential for host-defense against cytosolic bacteria and DNA viruses, Nat. Immunol., 11, 395, 10.1038/ni.1864
Rawlinson, 2017, Congenital cytomegalovirus infection in pregnancy and the neonate: consensus recommendations for prevention, diagnosis, and therapy, Lancet Infect. Dis., 17, e177, 10.1016/S1473-3099(17)30143-3
Reich, 2002, Nuclear/cytoplasmic localization of IRFs in response to viral infection or interferon stimulation, J. Interferon Cytokine Res. Off. J. Int. Soc. Interferon Cytokine Res., 22, 103, 10.1089/107999002753452719
Rossini, 2012, Interplay between human cytomegalovirus and intrinsic/innate host responses: a complex bidirectional relationship, Mediators Inflamm., 2012, 607276, 10.1155/2012/607276
Saffert, 2006, Inactivating a cellular intrinsic immune defense mediated by Daxx is the mechanism through which the human cytomegalovirus pp71 protein stimulates viral immediate-early gene expression, J. Virol., 80, 3863, 10.1128/JVI.80.8.3863-3871.2006
Salsman, 2008, Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies, PLoS Pathog., 4, 10.1371/journal.ppat.1000100
Salsman, 2011, Nuclear body formation and PML body remodeling by the human cytomegalovirus protein UL35, Virology, 414, 119, 10.1016/j.virol.2011.03.013
Schattgen, 2011, The PYHIN protein family as mediators of host defenses, Immunol. Rev., 243, 109, 10.1111/j.1600-065X.2011.01053.x
Scherer, 2016, Emerging role of PML nuclear bodies in innate immune signaling, J. Virol., 90, 5850, 10.1128/JVI.01979-15
Schoggins, 2011, A diverse range of gene products are effectors of the type I interferon antiviral response, Nature, 472, 481, 10.1038/nature09907
Schoggins, 2014, Pan-viral specificity of IFN-induced genes reveals new roles for cGAS in innate immunity, Nature, 505, 691, 10.1038/nature12862
Seo, 2013, Viperin regulates cellular lipid metabolism during human cytomegalovirus infection, PLoS Pathog., 9, 10.1371/journal.ppat.1003497
Seo, 2011, Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity, Science, 332, 1093, 10.1126/science.1202007
Shi, 2015, Inflammasome activation in mouse inner ear in response to MCMV induced hearing loss, J. Otol., 10, 143, 10.1016/j.joto.2015.12.001
Shin, 2012, The chromatin-tethering domain of human cytomegalovirus immediate-early (IE) 1 mediates associations of IE1, PML and STAT2 with mitotic chromosomes, but is not essential for viral replication, J. Gen. Virol., 93, 716, 10.1099/vir.0.037986-0
Shrivastava, 2016, Inflammasomes and its importance in viral infections, Immunol. Res., 64, 1101, 10.1007/s12026-016-8873-z
Simon, 2015, Intrinsic host restrictions to HIV-1 and mechanisms of viral escape, Nat. Immunol., 16, 546, 10.1038/ni.3156
Söderberg-Nauclér, 2001, Reactivation of latent human cytomegalovirus in CD14(+) monocytes is differentiation dependent, J. Virol., 75, 7543, 10.1128/JVI.75.16.7543-7554.2001
Srinivasula, 2002, The PYRIN-CARD protein ASC is an activating adaptor for caspase-1, J. Biol. Chem., 277, 21119, 10.1074/jbc.C200179200
Sun, 2013, Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway, Science, 339, 786, 10.1126/science.1232458
Suspène, 2005, Extensive editing of both hepatitis B virus DNA strands by APOBEC3 cytidine deaminases in vitro and in vivo, Proc. Natl. Acad. Sci. U. S. A., 102, 8321, 10.1073/pnas.0408223102
Szekely, 1999, Human herpesvirus-8-encoded LNA-1 accumulates in heterochromatin- associated nuclear bodies, J. Gen. Virol., 80, 2889, 10.1099/0022-1317-80-11-2889
Takaoka, 2007, DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response, Nature, 448, 501, 10.1038/nature06013
Takeuchi, 2010, Pattern recognition receptors and inflammation, Cell, 140, 805, 10.1016/j.cell.2010.01.022
Tavalai, 2008, New insights into the role of the subnuclear structure ND10 for viral infection, Biochim. Biophys. Acta, 1783, 2207, 10.1016/j.bbamcr.2008.08.004
Tavalai, 2006, Evidence for a role of the cellular ND10 protein PML in mediating intrinsic immunity against human cytomegalovirus infections, J. Virol., 80, 8006, 10.1128/JVI.00743-06
Tavalai, 2008, Nuclear domain 10 components promyelocytic leukemia protein and hDaxx independently contribute to an intrinsic antiviral defense against human cytomegalovirus infection, J. Virol., 82, 126, 10.1128/JVI.01685-07
Tavalai, 2011, Evidence for a dual antiviral role of the major nuclear domain 10 component Sp100 during the immediate-early and late phases of the human cytomegalovirus replication cycle, J. Virol., 85, 9447, 10.1128/JVI.00870-11
Taylor, 2005, Human cytomegalovirus immediate-early 2 gene expression blocks virus-induced beta interferon production, J. Virol., 79, 3873, 10.1128/JVI.79.6.3873-3877.2005
Taylor, 2006, Human cytomegalovirus immediate-early 2 protein IE86 blocks virus-induced chemokine expression, J. Virol., 80, 920, 10.1128/JVI.80.2.920-928.2006
Taylor-Wiedeman, 1991, Monocytes are a major site of persistence of human cytomegalovirus in peripheral blood mononuclear cells, J. Gen. Virol., 72, 2059, 10.1099/0022-1317-72-9-2059
Trilling, 2012, Interplay between CMVs and interferon signaling: implications for pathogenesis and therapeutic intervention, Future Microbiol., 7, 1269, 10.2217/fmb.12.109
Turelli, 2004, Inhibition of hepatitis B virus replication by APOBEC3G, Science, 303, 1829, 10.1126/science.1092066
Unterholzner, 2013, The interferon response to intracellular DNA: why so many receptors?, Immunobiology, 218, 1312, 10.1016/j.imbio.2013.07.007
Unterholzner, 2010, IFI16 is an innate immune sensor for intracellular DNA, Nat. Immunol., 11, 997, 10.1038/ni.1932
Vieira, 2013, The role of cytidine deaminases on innate immune responses against human viral infections, BioMed Res. Int., 2013, 683095, 10.1155/2013/683095
Wagenknecht, 2015, Contribution of the major ND10 proteins PML, hDaxx and Sp100 to the regulation of human cytomegalovirus latency and lytic replication in the monocytic cell line THP-1, Viruses, 7, 2884, 10.3390/v7062751
Weisblum, 2017, APOBEC3A is upregulated by human cytomegalovirus (HCMV) in the maternal-fetal interface, acting as an innate anti-HCMV effector, J. Virol., 91, 10.1128/JVI.01296-17
West, 2012, Toll-like receptor sensing of human herpesvirus infection, Front. Cell. Infect. Microbiol., 2, 122, 10.3389/fcimb.2012.00122
Wilkinson, 1998, Disruption of PML-associated nuclear bodies mediated by the human cytomegalovirus major immediate early gene product, J. Gen. Virol., 79, 1233, 10.1099/0022-1317-79-5-1233
Wills, 2015, The immunology of human cytomegalovirus latency: could latent infection be cleared by novel immunotherapeutic strategies?, Cell. Mol. Immunol., 12, 128, 10.1038/cmi.2014.75
Woodhall, 2006, Human Daxx-mediated repression of human cytomegalovirus gene expression correlates with a repressive chromatin structure around the major immediate early promoter, J. Biol. Chem., 281, 37652, 10.1074/jbc.M604273200
Xu, 2001, Proteasome-independent disruption of PML oncogenic domains (PODs), but not covalent modification by SUMO-1, is required for human cytomegalovirus immediate-early protein IE1 to inhibit PML-mediated transcriptional repression, J. Virol., 75, 10683, 10.1128/JVI.75.22.10683-10695.2001
Yamin, 1996, Activation of the native 45-kDa precursor form of interleukin-1-converting enzyme, J. Biol. Chem., 271, 13273, 10.1074/jbc.271.22.13273
Yew, 2010, Scavenger receptor A1 is required for sensing HCMV by endosomal TLR-3/-9 in monocytic THP-1 cells, Mol. Immunol., 47, 883, 10.1016/j.molimm.2009.10.009
Yurochko, 1999, Human cytomegalovirus binding to human monocytes induces immunoregulatory gene expression, J. Immunol. Baltim. Md, 1950, 4806
Zhang, 2017, Herpesvirus tegument and immediate early proteins are pioneers in the battle between viral infection and nuclear domain 10-related host defense, Virus Res., 238, 40, 10.1016/j.virusres.2017.05.023
Zhang, 2013, Cyclic GMP-AMP containing mixed phosphodiester linkages is an endogenous high-affinity ligand for STING, Mol. Cell, 51, 226, 10.1016/j.molcel.2013.05.022