Modulation of surface charge, particle size and morphological properties of chitosan–TPP nanoparticles intended for gene delivery

Colloids and Surfaces B: Biointerfaces - Tập 44 Số 2-3 - Trang 65-73 - 2005
Quan Gan1, Tao Wang, Colette Cochrane, Paul A. McCarron
1School of Chemical Engineering, Queen's University Belfast, Belfast BT9 5AG, UK. [email protected]

Tóm tắt

Từ khóa


Tài liệu tham khảo

Janes, 2001, Polysaccharide colloidal particles as delivery systems for macromolecules, Adv. Drug Deliv. Rev., 47, 83, 10.1016/S0169-409X(00)00123-X

Richardson, 1999, Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA, Int. J. Pharm., 178, 231, 10.1016/S0378-5173(98)00378-0

Cui, 2001, Chitosan-based nanoparticles for topical genetic immunization, J. Control. Release, 75, 409, 10.1016/S0168-3659(01)00407-2

Illum, 2001, Chitosan as a novel nasal delivery system for vaccines, Adv. Drug Deliv. Rev., 51, 81, 10.1016/S0169-409X(01)00171-5

Mislick, 1996, Evidence for the role of proteoglycans in cation-mediated gene transfer, Proc. Natl. Acad. Sci. USA, 93, 12349, 10.1073/pnas.93.22.12349

Panyam, 2003, Biodegradable nanoparticles for drug and gene delivery to cells and tissue, Adv. Drug Deliv. Rev., 55, 329, 10.1016/S0169-409X(02)00228-4

Corsi, 2003, Mesenchymal stem cells, MG63 and HEK293 transfection using chitosan–DNA nanoparticles, Biomaterials, 24, 1255, 10.1016/S0142-9612(02)00507-0

Romoren, 2002, Immersion delivery of plasmid DNA, J. Control. Release, 85, 215, 10.1016/S0168-3659(02)00279-1

Vinagradov, 2002, Nanosized cationic hydrogels for drug delivery: preparation, properties and interactions with cells, Adv. Drug Deliv. Rev., 54, 223

Ohya, 1994, Release behavior of 5-fluorouracil from chitosan-gel nanospheres immobilizing 5-fluorouracil coated with polysaccharides and their cell specific cytotoxicity, Pure Appl. Chem. A, 31, 629

Shu, 2000, A new approach to prepare tripolyphosphate/chitosan complex beads for controlled drug delivery, Int. J. Pharm., 201, 51, 10.1016/S0378-5173(00)00403-8

Song, 1998, Arterial uptake of biodegradable nanoparticles for intravascular local drug delivery: results with an acute dog model, J. Control. Release, 54, 201, 10.1016/S0168-3659(98)00016-9

Desai, 1996, Gastrointestinal uptake of biodegradable microparticles: effect of particle size, Pharm. Res., 13, 1838, 10.1023/A:1016085108889

Prabha, 2002, Size dependency of nanoparticles-mediated gene transfection: Studies with fractionnated nanoparticles, Int. J. Pharm., 244, 105, 10.1016/S0378-5173(02)00315-0

Paul, 2000, Chitosan a drug carrier for the 21st century S.T.P, Pharm. Sci., 10, 5

Dodane, 1998, Pharmaceutical applications of chitosan, Pharm. Sci. Technol. Today, 16, 246, 10.1016/S1461-5347(98)00059-5

Calvo, 1997, Effect of lysozyme on the stability of polyester nanocapsules and nanoparticles: stabilization approaches, Biomaterials, 18, 1305, 10.1016/S0142-9612(97)00061-6

Mi, 2003, Synthesis and characterization of biodegradable TPP/genipin co-crosslinked chitosan gel beads, Polymer, 44, 6521, 10.1016/S0032-3861(03)00620-7

Leong, 1998, DNA-polycation nanospheres as non-viral gene delivery vehicles, J. Control. Release, 53, 183, 10.1016/S0168-3659(97)00252-6

Ko, 2002, Preparation and characterization of chitosan microparticles intended for controlled drug delivery, J. Pharm., 249, 165

Shu, 2001, Novel PH–sensitive citrate cross-linked chitosan film for controlled drug release, Int. J. Pharm., 212, 19, 10.1016/S0378-5173(00)00582-2

Makino, 1986, Transfer of protons from bulk solution to the surface of poly(l-lactide) microcapsules, J. Microencapsul., 3, 195, 10.3109/02652048609031573

Xu, 2003, Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles, Int. J. Pharm., 250, 215, 10.1016/S0378-5173(02)00548-3