Modulation of oestrogen receptor signalling by association with the activated dioxin receptor

Nature - Tập 423 Số 6939 - Trang 545-550 - 2003
Fumiaki Ohtake1, Ken‐ichi Takeyama1, Takahiro Μatsumoto1, Hirochika Kitagawa1, Yasuji Yamamoto2, Keiko Nohara3, Chiharu Tohyama3, Andrée Krust4, Junsei Mimura5, Pierre Chambon4, Junn Yanagisawa6, Yoshiaki Fujii‐Kuriyama5, Shigeaki Kato6
1The Institute of Molecular and Cellular Biosciences, University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, 113-0032, Tokyo, Japan
2Taiho Pharmaceutical Company Ltd, Cancer Research Laboratory, Hanno Research Center, Hanno, Saitama, 357-8527, Japan
3National Institute for Environmental Studies, Tsukuba, Ibaraki 305-8506, Japan
4Institut de Génétique et de Biologie Moleculaire et Cellulaire, CNRS, INSERM, Université Louis Pasteur, Collège de France, 67404, Illkirch, Strasbourg, France
5CREST, Japan Science and Technology, Saitama, 332-0012, Kawaguchi, Japan
6SORST, Japan Science and Technology, Saitama, 332-0012, Kawaguchi, Japan

Tóm tắt

Từ khóa


Tài liệu tham khảo

Bock, K. W. Aryl hydrocarbon or dioxin receptor: biologic and toxic responses. Rev. Physiol. Biochem. Pharmacol. 125, 1–42 (1994)

Krishnan, V. et al. Molecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cells. Mol. Cell. Biol. 15, 6710–6719 (1995)

Astroff, B. et al. Inhibition of the 17β-estradiol-induced and constitutive expression of the cellular protooncogene c-fos by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the female rat uterus. Toxicol. Lett. 56, 305–315 (1991)

Gibbons, A. Dioxin tied to endometriosis. Science 262, 1373 (1993)

Mayani, A., Barel, S., Soback, S. & Almagor, M. Dioxin concentrations in women with endometriosis. Hum. Reprod. 12, 373–375 (1997)

Rier, S. E., Martin, D. C., Bowman, R. E., Dmowski, W. P. & Becker, J. L. Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam. Appl. Toxicol. 21, 433–441 (1993)

Cummings, A. M., Metcalf, J. L. & Birnbaum, L. Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time–dose dependence and species comparison. Toxicol. Appl. Pharmacol. 138, 131–139 (1996)

Brown, N. M., Manzolillo, P. A., Zhang, J. X., Wang, J. & Lamartiniere, C. A. Prenatal TCDD and predisposition to mammary cancer in the rat. Carcinogenesis 19, 1623–1629 (1998)

Davis, B. J., McCurdy, E. A., Miller, B. D., Lucier, G. W. & Tritscher, A. M. Ovarian tumors in rats induced by chronic 2,3,7,8-tetrachlorodibenzo-p-dioxin treatment. Cancer Res. 60, 5414–5419 (2000)

Sogawa, K. & Fujii-Kuriyama, Y. Ah receptor, a novel ligand-activated transcription factor. J. Biochem. (Tokyo) 122, 1075–1079 (1997)

Schmidt, J. V. & Bradfield, C. A. Ah receptor signaling pathways. Annu. Rev. Cell Dev. Biol. 12, 55–89 (1996)

Kato, S. et al. Activation of the estrogen receptor through phosphorylation by mitogen-activated protein kinase. Science 270, 1491–1494 (1995)

McKenna, N. J. & O'Malley, B. W. Combinatorial control of gene expression by nuclear receptors and coregulators. Cell 108, 465–474 (2002)

Mangelsdorf, D. J. et al. The nuclear receptor superfamily: the second decade. Cell 83, 835–839 (1995)

Freedman, L. P. Increasing the complexity of coactivation in nuclear receptor signaling. Cell 97, 5–8 (1999)

Watanabe, M. et al. A subfamily of RNA-binding DEAD-box proteins acts as an estrogen receptor alpha coactivator through the N-terminal activation domain (AF-1) with an RNA coactivator, SRA. EMBO J. 20, 1341–1352 (2001)

Yanagisawa, J. et al. Nuclear receptor function requires a TFTC-type histone acetyl transferase complex. Mol. Cell 9, 553–562 (2002)

Kamei, Y. et al. A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors. Cell 85, 403–414 (1996)

Tian, Y., Ke, S., Thomas, T., Meeker, R. J. & Gallo, M. A. Transcriptional suppression of estrogen receptor gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). J. Steroid Biochem. Mol. Biol. 67, 17–24 (1998)

Tora, L. et al. The human estrogen receptor has two independent nonacidic transcriptional activation functions. Cell 59, 477–487 (1989)

Kobayashi, Y. et al. p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains. J. Biol. Chem. 275, 15645–15651 (2000)

Mimura, J., Ema, M., Sogawa, K. & Fujii-Kuriyama, Y. Identification of a novel mechanism of regulation of Ah (dioxin) receptor function. Genes Dev. 13, 20–25 (1999)

Beischlag, T. V. et al. Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex. Mol. Cell. Biol. 22, 4319–4333 (2002)

Daitoku, H. Y. K., Matsuzaki, H., Hatta, M. & Fukamizu, A. Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR. Diabetes 52, 642–649 (2003)

Weisz, A. & Rosales, R. Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor. Nucleic Acids Res. 18, 5097–5106 (1990)

Mueller, M. D. et al. Regulation of vascular endothelial growth factor (VEGF) gene transcription by estrogen receptors alpha and beta. Proc. Natl Acad. Sci. USA 97, 10972–10977 (2000)

Puga, A., Nebert, D. W. & Carrier, F. Dioxin induces expression of c-fos and c-jun proto-oncogenes and a large increase in transcription factor AP-1. DNA Cell Biol. 11, 269–281 (1992)

Mimura, J. et al. Loss of teratogenic response to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in mice lacking the Ah (dioxin) receptor. Genes Cells 2, 645–654 (1997)

Dupont, S. et al. Effect of single and compound knockouts of estrogen receptors α (ERα) and β (ERβ) on mouse reproductive phenotypes. Development 127, 4277–4291 (2000)

Kuchenhoff, A. et al. Arylhydrocarbon receptor expression in the human endometrium. Fertil. Steril. 71, 354–360 (1999)