Modulation of immunity by thymus-derived lymphocytes

Abdou, 1976, Suppressor T-cell abnormality in idiopathic systemic lupus erythematosus, Clin. Immunol. Immunopathol., 6, 192, 10.1016/0090-1229(76)90110-0 Ahmed, 1977, B-lymphocyte heterogeneity: Development and characterization of an alloantiserum which distinguishes B-lymphocyte differentiation alloantigens, J. exp. Med., 145, 101, 10.1084/jem.145.1.101 Allison, 1974, The role of T and B lymphocytes in self tolerance and autoimmunity, Contemp. Top. Immunobiol., 3, 227, 10.1007/978-1-4684-3045-5_9 Allison, 1974, Interactions of T and B lymphocytes in self-tolerance and autoimmunity, 22 Ambrose, 1969, Regulation of the secondary antibody response in vitro. Enhancement by Actinomycin D and inhibition by a macromolecular product of stimulated lymph node cultures, J. exp. Med., 130, 1003, 10.1084/jem.130.5.1003 Andersson, 1970, Evidence for a small pool of immunocompetent cells in the mouse thymus. Its role in the humoral antibody response against sheep erythrocytes, bovine serum albumin, ovalbumin and the NIP determinant, Cell. Immunol., 1, 362, 10.1016/0008-8749(70)90014-6 Andersson, 1971, Evidence for thymus-independent humoral antibody production in mice against polyvinylpyrrolidone and E. coli lipopolysaccharide, Cell. Immunol., 2, 411, 10.1016/0008-8749(71)90052-9 Araneo, 1975, Functional heterogeneity among T-derived lymphocytes of the mouse. II. Sensitivity of subpopulations to anti-thymocyte serum, J. Immunol., 114, 747, 10.4049/jimmunol.114.2_Part_2.747 Araneo, 1976, Functional heterogeneity among the T-derived lymphocytes of the mouse. VI. Memory T cells stored in the T2 subpopulation, J. Immunol., 117, 2131, 10.4049/jimmunol.117.6.2131 Armerding, 1974, Activation of T and B lymphocytes in vitro. II. Biological and biochemical properties of an allogeneic effect factor (AEF) active in triggering specific B lymphocytes, J. exp. Med., 140, 19, 10.1084/jem.140.1.19 Armerding, 1974, Activation of T and B lymphocytes in vitro. III. Presence of Ia determinants on allogeneic effect factor, J. exp. Med., 140, 1717, 10.1084/jem.140.6.1717 Armstrong, 1969, Antigen-reactive cells in normal, immunized and tolerant mice, J. exp. Med., 129, 393, 10.1084/jem.129.2.393 Asherson, 1974, T cell suppression of contact sensitivity in the mouse. III. The role of macrophages and the specific triggering of nonspecific suppression, Eur. J. Immunol., 4, 804, 10.1002/eji.1830041207 Askonas, 1974, The differentiative function of T cell replacing factor in nu/nu spleen cell cultures, Eur. J. Immunol., 4, 164, 10.1002/eji.1830040304 Bach, 1977, Cellular recognition of major histocompatibility complex antigens Bach, 1976, Differential functions of major histocompatibility complex antigens in T-lymphocyte activation, Nature, 259, 273, 10.1038/259273a0 Bach, 1973, Cell mediated immunity: separation of cells involved in recognitive and destructive phases, Science, 180, 403, 10.1126/science.180.4084.403 Baker, 1970, Enhancement of the antibody response to type III pneumococcal polysaccharide in mice treated with anti-lymphocyte serum, J. Immunol., 104, 1313, 10.4049/jimmunol.104.5.1313 Baker, 1974, Regulation of the antibody response to type III pneumococcal polysaccharide. II. Mode of action of thymic-derived suppressor cells, J. Immunol., 112, 404, 10.4049/jimmunol.112.1.404 Baker, 1970, Evidence for the existence of two functionally distinct types of cells which regulate the antibody response of type III pneumococcal polysaccharide, J. Immunol., 105, 1581, 10.4049/jimmunol.105.6.1581 Bash, 1975, The suppressive effect of immunization on the proliferative responses of rat T cells in vitro, J. Immunol., 114, 782, 10.4049/jimmunol.114.2_Part_2.782 Basten, 1973, Thymus independence, Contemp. Top. Immunobiol., 2, 265, 10.1007/978-1-4684-0919-2_17 Basten, 1975, T cell-dependent suppression of an anti-hapten antibody response, Transplant. Rev., 26, 130 Basten, 1974, Cell-to-cell interaction in the immune response. X. T-cell-dependent suppression in tolerant mice, J. exp. Med., 140, 199, 10.1084/jem.140.1.199 Benacerraf, 1976, The nature and function of specific H-linked immune response genes and immune suppression genes, 225 Benacerraf, 1975, The stimulation of specific suppressor T cells in genetic nonresponder mice by linear random copolymers of L-amino acid, Transplant. Rev., 26, 21 Beverley, 1976, Separation of suppressor and killer T cells by surface phenotype, Nature, 262, 495, 10.1038/262495a0 Binz, 1975, Shared idiotypic determinants on B and T lymphocytes reactive against the same antigenic determinants. I. Demonstration of similar or identical idiotypes on IgG molecules and T-cell receptors with specificity for the same alloantigens, J. exp. Med., 142, 197, 10.1084/jem.142.1.197 Bloom, 1971, In vitro approaches to the mechanism of cell-mediated immune reactions, Adv. Immunol., 13, 102 Boyse, 1971, Ly-C: A third locus specifying alloantigens expressed only on thymocytes and lymphocytes, Transplantation, 11, 351, 10.1097/00007890-197103000-00021 Boyse, 1968, Ly-A and Ly-B: Two systems of lymphocyte isoantigens in the mouse, 170, 175 Bretscher, 1975, The two signal model for B cell induction, Transplant. Rev., 23, 37 Bretscher, 1970, A theory of non-self discrimination, Science, 169, 1042, 10.1126/science.169.3950.1042 Bullock, 1975, Induction of T-lymphocyte responses to a small molecular weight antigen. III. T-T cell interations to determinants linked together: suppression vs. enhancement, J. exp. Med., 142, 275, 10.1084/jem.142.2.275 Burnet, 1959 Burnet, 1974, Autoimmunity and aging, Prog. Immunol. II, 5, 27 Cantor, 1970, Synergy among lymphoid cells mediating the graft-vs.-host (GVH) response. II. Synergy and GVH reactions produced by BALB/c lymphoid cells of differing anatomic origin, J. exp. Med., 131, 235, 10.1084/jem.131.2.235 Cantor, 1972, Synergy among lymphoid cells mediating the graft-vs-host response. III. Evidence for interaction between two types of thymus derived cells, J. exp. Med., 135, 764, 10.1084/jem.135.4.764 Cantor, 1975, Functional subclasses of T lymphocytes bearing different Ly antigens. I. The generation of functionally distinct T-cell subclasses is a differentiative process independent of antigen, J. exp. Med., 141, 1376, 10.1084/jem.141.6.1376 Cantor, 1975, Functional subclasses of T lymphocytes bearing different Ly antigens. II. cooperation between subclasses of Ly+ cells in the generation of killer activity, J. exp. Med., 141, 1390, 10.1084/jem.141.6.1390 Cantor, 1976, Separation of helper T cells from suppressor T cells expressing different Ly components. II. Activation by antigen: after immunization, antigen-specific suppressor and helper activities are mediated by distinct T-cell subclasses, J. exp. Med., 143, 1391, 10.1084/jem.143.6.1391 Cantor, 1975, Characterization of subpopulations of T lymphocytes. I. Separation and functional studies of peripheral T-cells binding different amounts of fluorescent anti-Thy-1.2 (Theta) antibody using a fluorescence-activated cell sorter (FACS), Cell. Immunol., 15, 180, 10.1016/0008-8749(75)90174-4 Cantor, 1976, Development and function of subpopulations of thymocytes and T lymphocytes, Prog. Allergy, 20, 2 Cerottini, 1974, Cell-mediated cytotoxicity, allograft rejection, and tumor immunity, Adv. Immunol., 18, 67, 10.1016/S0065-2776(08)60308-9 Cinader, 1974, The role of accessory and thymus-derived cells in resistance to tolerance induction, 67 Claman, 1966, Thymus-marrow cell combinations. Synergism in antibody production, 122, 1167 Claman, 1974, Tolerance to contact sensitivity—a role for suppressor T cells?, 123 Cohen, 1973, Synergism between subpopulations of thymus-derived cells mediating the proliferative and effector phases of the mixed lymphocyte reaction, 70, 2707 Cowing, 1974, The cellular basis for establishing tolerance or immunity to bovine γ-globulin in mice, 61 David, 1975, Macrophage activation by lymphocyte mediators, 34, 1730 David, 1972, Cellular hypersensitivity and immunity. Inhibition of macrophage migration and the lymphocyte mediators, Prog. Allergy, 16, 300, 10.1159/000313176 Davie, 1974, Role of T lymphocytes in the humoral immune response. I. Proliferation of B lymphocytes in thymus-deprived mice, J. Immunol., 113, 1445, 10.4049/jimmunol.113.5.1438 Davies, 1969, The thymus and the cellular basis of immunity, Transplant. Rev., 1, 43 Dresser, 1968, The mechanism of immunological paralysis, Adv. Immunol., 8, 129, 10.1016/S0065-2776(08)60466-6 Droege, 1971, Amplifying and suppressive effects of thymus cells, Nature, 234, 549, 10.1038/234549a0 Droege, 1972, Cellular heterogeneity in the thymus. I. Electrophoretic analysis of lymphoid cell populations from chickens, Eur. J. Immunol., 2, 156, 10.1002/eji.1830020212 Durkin, 1975, Separation of T cell subpopulations capable of DNA synthesis, lymphotoxin release, and regulation of antigen and phytohemagglutinin response on the basis of density and adherence properties, 72, 5090 Dutton, 1972, Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. I. Characterization of the inhibitory cell activity, J. exp. Med., 136, 1445, 10.1084/jem.136.6.1445 Dutton, 1973, Inhibitory and stimulatory effects of concanavalin A on the response of mouse spleen cell suspensions to antigen. II. Evidence for separate stimulatory and inhibitory cells, J. exp. Med., 138, 1496, 10.1084/jem.138.6.1496 Dutton, 1975, Suppressor T cells, Transplant. Rev., 26, 39 Dutton, 1971, Is there evidence for a non-antigen specific diffusable chemical mediator in the initiation of the immune response?, Prog. Immunol., 1, 355, 10.1016/B978-0-12-057550-3.50033-8 Eardley, 1975, Feedback inhibitors of suppressor T-cell activity, J. exp. Med., 142, 524, 10.1084/jem.142.2.524 Eardley, 1976, Induction of specific suppressor T cells in vitro, J. Immunol., 117, 313, 10.4049/jimmunol.117.1.313 Eardley, 1976, Modulation of help and suppression in a hapten-carrier system, J. Immunol., 116, 600, 10.4049/jimmunol.116.3.600 Edelman, 1976, Surface modulation in cell recognition and cell growth, Science, 192, 218, 10.1126/science.769162 Eichmann, 1975, Idiotype suppression. II. Amplification of a suppressor T cell with anti-idiotypic activity, Eur. J. Immunol., 5, 511, 10.1002/eji.1830050802 Eichmann, 1975, Induction of T and B cell immunity by anti-idiotypic antibody, Eur. J. Immunol., 5, 661, 10.1002/eji.1830051002 Eijsvoogel, 1973, The specificity and activation mechanism of cell-mediated lympholysis (CML) in man, 5, 1675 Engers, 1976, Generation of cytolytic T lymphocytes in vitro, Contemp. Top. Immunobiol., 5, 145 Erb, 1975, The role of macrophages in the generation of T-helper cells. II. The genetic control of the macrophage-T-cell interaction for helper cell induction with soluble antigens, J. exp. Med., 142, 460, 10.1084/jem.142.2.460 Erb, 1976, Role of macrophages in the generation of T helper cells. IV. Nature of genetically related factor derived from macrophages incubated with soluble antigens, Eur. J. Immunol., 6, 365, 10.1002/eji.1830060512 Erb, 1976, Two-gene control of T-helper cell induction, Nature, 263, 601, 10.1038/263601a0 Feldmann, 1972, Cell interactions in the immune response in vitro. V. Specific collaboration via complexes of antigen and thymus-derived cell immunoglobulin, J. exp. Med., 136, 737, 10.1084/jem.136.4.737 Feldmann, 1974, T cell suppression in vitro. I. Role in regulation of antibody response, Eur. J. Immunol., 4, 660, 10.1002/eji.1830041005 Feldmann, 1976, Lymphoid cell interactions in Japan, Nature, 269, 12, 10.1038/264012a0 Feldmann, 1972, Cell interactions in the immune response in vitro. III. Specific collaboration across a cell impermeable membrane, J. exp. Med., 136, 49, 10.1084/jem.136.1.49 Feldmann, 1975, Different Ly antigen phenotypes of in vitro induced helper and suppressor cells, Nature, 258, 614, 10.1038/258614a0 Feldmann, 1975, T-T interaction in the generation of helper cells in vitro, Nature, 256, 741, 10.1038/256741a0 Feldmann, 1976, Suppressor cell induction in vitro. II. Cellular requirements of suppressor cell induction, Eur. J. Immunol., 6, 302, 10.1002/eji.1830060413 Fitch, 1975, Generation of cytotoxic T lymphocytes in vitro. VI. Effect of cell density on response in mixed leukocyte cultures, J. Immunol., 115, 1688, 10.4049/jimmunol.115.6.1688 Folch, 1974, The splenic suppressor cell. I. Activity of thymus-dependent adherent cells: changes with age and stress, J. Immunol., 113, 127, 10.4049/jimmunol.113.1.127 Folch, 1974, The splenic suppressor cell. II. Suppression of the mixed lymphocyte reaction by thymus-dependent adherent cells, J. Immunol., 113, 140, 10.4049/jimmunol.113.1.140 Gelfand, 1975, Prolongation of allograft survival in mice by administration of anti-Thy-1 serum. I. Mediation by in vivo activation of regulatory T cells, J. Immunol., 115, 1, 10.4049/jimmunol.115.1.1 Gerbase-DeLima, 1975, Age related changes, including synergy and suppression in the mixed lymphocyte reaction in long-lived mice, 34, 159 Gershon, 1974, T cell control of antibody production, Contemp. Top. Immunobiol., 3, 1, 10.1007/978-1-4684-3045-5_1 Gershon, 1975, A disquisition on suppressor T cells, Transplant. Rev., 26, 170 Gershon, 1974, Suppressive effects of in vivo immunization on PHA responses in vitro, J. Immunol., 112, 215, 10.4049/jimmunol.112.1.215 Gershon, 1971, The DNA synthetic response of adoptively transferred thymocytes in the spleens of lethally irradiated mice. I. Effects of varying antigen and thymocyte dose, J. Immunol., 107, 1723, 10.4049/jimmunol.107.6.1723 Gershon, 1974, Immunoregulatory role of spleen localizing thymocytes, J. Immunol., 112, 546, 10.4049/jimmunol.112.2.546 Gershon, 1972, The response of T cells to histocompatibility-2 antigens. Dose-response kinetics, J. exp. Med., 136, 112, 10.1084/jem.136.1.112 Good, 1974, Association of autoimmunity, immunodeficiency and aging in man, rabbits and mice, 33, 2040 Gorczynski, 1975, B-cell heterogeneity: difference in the size of B lymphocytes responding to T-dependent and T-independent antigens, Cell. Immunol., 18, 88, 10.1016/0008-8749(75)90039-8 Gronowicz, 1975, Functional analysis of B-cell heterogeneity, Transplant. Rev., 24, 3 Ha, 1973, Role of the thymus in tolerance. X. Suppressor activity of antigen-stimulated rat thymocytes transferred to normal recipients, J. Immunol., 110, 1290, 10.4049/jimmunol.110.5.1290 Harwell, 1977, Suppressor T-cell inactivation of a helper T-cell factor, Nature, 265, 57, 10.1038/265057a0 Heber-Katz, 1975, Collaboration of allogeneic T and B lymphocytes in the primary antibody response to sheep erythrocytes in vitro, J. exp. Med., 142, 928, 10.1084/jem.142.4.928 Herzenberg, 1976, T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells, J. exp. Med., 144, 330, 10.1084/jem.144.2.330 Herzenberg, 1976, Regulation of immunoglobulin and antibody production by allotype suppressor T cells in mice, Transplant. Rev., 27, 57 Hirano, 1976, Cell-mediated immune response in vitro. I. The development of suppressor cells and cytotoxic lymphocytes in mixed lymphocyte cultures, J. Immunol., 116, 1115, 10.4049/jimmunol.116.4.1115 Hirano, 1976, Cell-mediated immune response in vitro. II. The mechanism(s) involved in the suppression of the development of cytotoxic lymphocytes, J. Immunol., 117, 2226, 10.4049/jimmunol.117.6.2226 Hoffman, 1977, Suppression of erythroid-colony formation by lymphocytes from patients with aplastic anemia, New Engl. J. Med., 296, 10, 10.1056/NEJM197701062960103 Howard, 1973, Biological effects of Corynebacterium parvum. IV. Adjuvant and inhibitory activities on B lymphocytes, Cell. Immunol., 7, 290, 10.1016/0008-8749(73)90251-7 Howe, 1975, Lymphoid cell subpopulations. I. Synergy between lymph node cells and thymocytes in response to alloantigens and mitogens, J. Immunol., 115, 1227, 10.4049/jimmunol.115.5.1227 Howe, 1975, Lymphoid cell subpopulations. II. Characterization of cell populations responsible for synergy in the mixed lymphocyte interaction, J. Immunol., 115, 1233, 10.4049/jimmunol.115.5.1233 Huber, 1976, Independent differentiative pathways of Ly 1 and Ly 23 subclasses of T cells. Experimental production of mice deprived of selected T-cell subclasses, J. exp. Med., 144, 1128, 10.1084/jem.144.4.1128 Huber, 1976, Cell-mediated immunity: delayed-type hypersensitivity and cytotoxic responses are mediated by different T-cell subclasses, J. exp. Med., 143, 1534, 10.1084/jem.143.6.1534 Ishizaka, 1976, Generation of specific helper cells and suppressor cells in vitro for the IgE and IgG antibody response, J. Immunol., 117, 40, 10.4049/jimmunol.117.1.40 Jacobsson, 1974, Enhancement of the mixed lymphocyte response in the mouse by the addition of thymocytes, Cell. Immunol., 10, 294, 10.1016/0008-8749(74)90121-X Jandinski, 1976, Separation of helper T cells from suppressor T cells expressing different Ly components. I. Polyclonal activation: Suppressor and helper activities are inherent properties of distinct T-cell subclasses, J. exp. Med., 143, 1382, 10.1084/jem.143.6.1382 Janossy, 1975, Functional analysis of murine and human B lymphocyte subsets, Transplant. Rev., 24, 177 Kapp, 1974, Genetic control of immune responses in vitro. III. Tolerogeneic properties of the terpolymer L-glutamic acid60-alanine30-L-tyrosine10 (GAT) for spleen cells from nonresponder (H-2s and H-2q) mice, J. exp. Med., 140, 172, 10.1084/jem.140.1.172 Kapp, 1975, Role of suppressor T cells in an IR gene controlled immune response, 84 Kapp, 1977, Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT) II. Cellular source and effect on responder and nonresponder mice, J. exp. Med., 10.1084/jem.145.4.828 Kapp, 1974, Genetic control of immune responses in vitro. V. Stimulation of suppressor T cells in nonresponder mice by the terpolymer L-glutamic acid60-L-alanine30-L-tyrosine10 (GAT), J. exp. Med., 140, 648, 10.1084/jem.140.3.648 Kappler, 1974, Functional heterogeneity among the T-derived lymphocytes of the mouse. I. Analysis by adult thymectomy, J. Immunol., 113, 27, 10.4049/jimmunol.113.1.27 Katz, 1972, The regulatory influence of activated T cells on B cell responses to antigen, Adv. Immunol., 15, 1, 10.1016/S0065-2776(08)60683-5 1974 Katz, 1976, Cell interactions between histoincompatible T and B lymphocytes. IX. The failure of histoincompatible cells is not due to suppression and cannot be circumvented by carrier-priming T cells with allogeneic macrophages, J. Immunol., 117, 1853, 10.4049/jimmunol.117.5_Part_2.1853 Katz, 1975, Cell interactions between histoincompatible T and B lymphocyts. VIII. Cooperative responses between lymphocytes are controlled by genes in the I region of the H-2 complex, J. exp. Med., 141, 263, 10.1084/jem.141.1.263 Katz, 1970, Carrier functions in anti-hapten immune responses. I. Enhancement of primary and secondary anti-hapten antibody responses by carrier preimmunization, J. exp. Med., 132, 261, 10.1084/jem.132.2.261 Katz, 1971, Carrier function in anti-hapten antibody responses. III. Stimulation of antibody synthesis and facilitation of hapten-specific secondary antibody responses by graft-versus-host reactions, J. exp. Med., 133, 169, 10.1084/jem.133.2.169 Kerbel, 1971, Variable effects of antilymphocyte serum on humoral antibody formation. Role of thymus-dependency of antigen, J. Immunol., 106, 917, 10.4049/jimmunol.106.4.917 Kerbel, 1972, Enhanced immune responsiveness to a thymus independent antigen. Evidence for a short-lived subpopulation of inhibitory thymus-derived lymphocytes, Eur. J. Immunol., 2, 114, 10.1002/eji.1830020204 Kisielow, 1975, Ly antigens: markers for functionally distinct subsets of thymus-derived lymphocytes of the mouse, Nature, 253, 219, 10.1038/253219a0 Klein, 1975 Kontiainen, 1976, Suppressor cell induction in vitro. I. Kinetics of induction of antigen-specific suppressor cells, Eur. J. Immunol., 6, 296, 10.1002/eji.1830060412 Krakauer, 1976, Loss of suppressor T cells in adult NZB/NZW mice, J. exp. Med., 144, 662, 10.1084/jem.144.3.662 1969 Liacopoulos, 1975, Antigenic competition, Prog. Allergy, 18, 97 Makinodan, 1975, Effects of aging on the differentiation and proliferation potentials of cells of the immune system, 34, 153 Marbrook, 1967, Primary immune response in cultures of spleen cells, Lancet, ii, 1279, 10.1016/S0140-6736(67)90393-5 McDevitt, 1976, Genetic and functional analysis of the Ia antigens, their possible role in regulating the immune response, Transplant. Rev., 30, 197 McGregor, 1976, Role of lymphocytes in cellular resistance to infection, Contemp. Top. Immunobiol., 5, 237 Miller, 1968, Cell to cell interaction in the immune response. I. Hemolysin-forming cells in neonatally thymectomized mice reconstituted with thymus or thoracic duct lymphocyte, J. exp. Med., 128, 801, 10.1084/jem.128.4.801 Miller, 1969, Thymus and antigen-reactive cells, Transplant. Rev., 1, 3 Miller, 1971, Cell to cell interaction in the immune response. VII Requirement for differentiation of thymus derived cells, J. exp. Med., 134, 1266, 10.1084/jem.134.5.1266 Miller, 1975, H-2 gene complex restricts transfer of delayed type hypersensitivity in mice, 72, 5095 Mishell, 1967, Immunization of normal mouse spleen cell suspensions in vitro, Science, 153, 1004, 10.1126/science.153.3739.1004 Mitchell, 1968, Cell to cell interaction in the immune response. II. The source of hemolysin-forming cells in irradiated mice given bone marrow and thymus or thoracic duct lymphocytes, J. exp. Med., 128, 821, 10.1084/jem.128.4.821 Mitchison, 1969, Cell populations involved in immune responses, 149 Mitchison, 1971, Carrier effects in secondary responses to hapten protein conjugates. I. Measurement of the effect with transferred cells and objection to the local environment hypothesis, Eur. J. Immunol., 1, 10, 10.1002/eji.1830010103 Mitchison, 1971, Carrier effects on the secondary immune response. II. Cellular cooperation, Eur. J. Immunol., 1, 18, 10.1002/eji.1830010104 Mitchison, 1970, Cooperation of antigenic determinants and of cells in the induction of antibodies, 547 1975, 26, 1 Möller, 1971, Frequency of antigen-sensitive cells to thymus independent antigens, Cell. Immunol., 2, 309, 10.1016/0008-8749(71)90065-7 Mosier, 1971, Functional maturation of mouse thymic lymphocytes, Eur. J. Immunol., 1, 459, 10.1002/eji.1830010610 Mosier, 1975, Ontogeny of mouse function, 34, 137 Mosier, 1975, Ontogeny of mouse lymphocyte functions. II. Development of the ability to produce antibody is modulated by T lymphocytes, J. exp. Med., 139, 1354, 10.1084/jem.139.5.1354 Munro, 1975, Two genes in the major histocompatibility complex control immune response, Nature, 256, 103, 10.1038/256103a0 1976 Okumura, 1976, Selective expression of H-2 (I-region) loci controlling determinants on helper and suppressor T lymphocytes, J. exp. Med., 144, 685, 10.1084/jem.144.3.685 Okumura, 1971, Regulation of homocytotropic antibody formation in the rat. VI. Inhibitory effect of thymocytes on the homocytotropic antibody response, J. Immunol., 107, 1682, 10.4049/jimmunol.107.6.1682 Okumura, 1973, Suppression of hapten-specific antibody response by carrier specific T cells, Nature New Biol., 245, 180, 10.1038/newbio245180a0 Paul, 1976, In general discussion of Session IV, Genetic control of cell interactions, 433 Paul, 1970, Carrier function in anti-hapten immune responses. II. Specific properties of carrier cells capable of enhancing antihapten antibody responses, J. exp. Med., 132, 283, 10.1084/jem.132.2.283 Peavy, 1974, Cell-mediated immune responses in vitro. I. Suppression of the generation of cytotoxic lymphocytes by concanavalin A and concanavalin A-activated spleen cells, J. exp. Med., 140, 356, 10.1084/jem.140.2.356 Pierce, 1976, Cellular basis of immune responses, 3 Pierce, 1976, Regulation of immune responses by suppressor T cells, Contemp. Top. Immunobiol., 5, 91 Pierce, 1976, Regulation by the H-2 complex of macrophagelymphoid cell interactions in secondary antibody responses in vitro, J. exp. Med., 144, 371, 10.1084/jem.144.2.371 Pierce, 1975, Suppressor T cells as regulators of lymphocyte functions, Ann. N. Y. Acad. Sci., 256, 365, 10.1111/j.1749-6632.1975.tb36063.x Pierce, 1975, Characterization of a soluble immune response suppressor (SIRS) produced by concanavalin A-activated spleen cells, 583 Piquet, 1975, Synergistic and suppressive interactions among mouse T lymphocytes in the response to phytohemagglutinin, J. exp. Med., 142, 1591, 10.1084/jem.142.6.1591 Pross, 1974, Antigenic competition: A review of nonspecific antigen-induced suppression, Adv. Immunol., 18, 133, 10.1016/S0065-2776(08)60309-0 Raff, 1970, Role of thymus-derived lymphocytes in the secondary humoral response in mice, Nature, Lond., 226, 1257, 10.1038/2261257a0 Raff, 1976, T cell recognition at Cold Spring Harbor, Nature, 263, 10, 10.1038/263010a0 Raff, 1971, Subpopulations of thymus cells and thymus-derived lymphocytes, Prog. Immunol., 1, 83, 10.1016/B978-0-12-057550-3.50013-2 Rich, 1975, Antibody synthesis and immunological memory in concanavalin A-treated mice, Clin. Immunol. Immunopath., 3, 482, 10.1016/0090-1229(75)90073-2 Rich, 1973, Biological expressions of lymphocyte activation. I. Effect of phytomitogens on antibody synthesis in vitro, J. exp. Med., 137, 205, 10.1084/jem.137.2.205 Rich, 1973, Biological expressions of lymphocyte activation. II. Generation of a population of thymus-derived suppressor lymphocytes, J. exp. Med., 137, 649, 10.1084/jem.137.3.649 Rich, 1974, Biological expressions of lymphocyte activation. III. Suppression of plaque-forming cell responses in vitro by supernatant fluids from concanavalin A-activated spleen cell cultures, J. Immunol., 112, 1360, 10.4049/jimmunol.112.4.1360 Rich, 1975, Biological expressions of lymphocyte activation. IV. Concanavalin A-activated suppressor cells in mouse mixed lymphocyte reactions, J. Immunol., 114, 1112, 10.4049/jimmunol.114.3.1112 Rich, 1976, Suppression of mixed lymphocyte reactions by alloantigen-activated spleen-localizing thymocytes, Cell. Immunol., 22, 358, 10.1016/0008-8749(76)90037-X Rich, 1974, Regulatory mechanisms in cell-mediated immune responses. I. Regulation of mixed lymphocyte reactions by alloantigen-activated thymus-derived lymphocytes, J. exp. Med., 140, 1588, 10.1084/jem.140.6.1588 Rich, 1975, Regulatory mechanisms in cell-mediated immune responses. II. A genetically restricted suppressor of mixed lymphocyte reactions released by alloantigen-activated spleen cells, J. exp. Med., 142, 1391, 10.1084/jem.142.6.1391 Rich, 1976, Regulatory mechanisms in cell-mediated immune responses. III. I-region control of suppressor cell interactions with responder cells in mixed lymphocyte reactions, J. exp. Med., 143, 672, 10.1084/jem.143.3.672 Rich, 1976, Regulatory mechanisms in cell-mediated immune responses. IV. Expression of a receptor for MLR suppressor factor on activated T lymphocytes, J. exp. Med., 144, 1214, 10.1084/jem.144.5.1214 Rich, 1977, H-2 and non H-2 gene control of T cell suppression of MLR Rosenthal, 1973, Function of macrophages in antigen recognition by guinea pig T lymphocytes. I. Requirement for histocompatible macrophages and lymphocytes, J. exp. Med., 138, 1194, 10.1084/jem.138.5.1194 Rosenthal, 1976, The function of macrophages in T-lymphocyte antigen recognition, Contemp. Top. Immunobiol., 5, 47 Rotter, 1974, Thymus cell population exerting a regulatory function in the immune response of mice to polyvinylpyrrolidone, Cell. Immunol., 13, 76, 10.1016/0008-8749(74)90228-7 Schendel, 1973, The involvement of LD- and SD-region differences in MLR and CML: A three-cell experiment, 5, 1651 Scher, 1976, B-lymphocyte heterogeneity: ontogenetic development and organ distribution of B-lymphocyte populations defined by their density of surface immunoglobulin, J. exp. Med., 144, 494, 10.1084/jem.144.2.494 Schimpl, 1971, Reconstitution of a thymus cell-deprived immune system by syngeneic and allogeneic thymocytes in vitro, Eur. J. Immunol., 1, 304, 10.1002/eji.1830010419 Schimpl, 1972, Replacement of T cell function by a T cell product, Nature New Biol., 237, 15, 10.1038/newbio237015a0 Schimpl, 1975, A third signal in B cell activation given by TRF, Transplant. Rev., 23, 176 Schreffler, 1976, The S region of the mouse major histocompatibility complex (H-2): Genetic variation and functional role in complement system, Transplant. Rev., 32, 140 Schreffler, 1975, The H-2 major histocompatibility complex and the I immune response region: genetic variation, function, and organization, Adv. Immunol., 20, 125, 10.1016/S0065-2776(08)60208-4 Schreffler, 1976, Genetic resolution of the products and functions of I and S region genes of the mouse H-2 complex, 3 Shiku, 1975, Expression of T-cell differentiation antigens on effector cells in cell-mediated cytotoxicity in vitro. Evidence for functional heterogeneity related to the surface phenotype of T-cells, J. exp. Med., 141, 227, 10.1084/jem.141.1.227 Shou, 1976, Suppressor cell activity after concanavalin A treatment of lymphocytes from normal donors, J. exp. Med., 143, 1100, 10.1084/jem.143.5.1100 Siegal, 1976, Suppression of B-cell differentiation by leukocytes from hypogammaglobulinemia patients, J. clin. Invest., 58, 109, 10.1172/JCI108439 Simpson, 1975, Regulation of the immune response by subclasses of T lymphocytes. II. The effect of adult thymectomy upon humoral and cellular responses in mice, Eur. J. Immunol., 5, 337, 10.1002/eji.1830050509 Sondel, 1975, Pre-emption of human cell-mediated lympholysis by a suppressive mechanism activated in mixed lymphocyte cultures, J. exp. Med., 142, 1606, 10.1084/jem.142.6.1606 Sprent, 1976, Helper function of T cells depleted of alloantigen-reactive lymphocytes by filtration through irradiated F1 hybrid recipients. I. Failure to collaborate with allogeneic B cells in a secondary response to sheep erythrocytes measured in vivo, J. exp. Med., 144, 617, 10.1084/jem.144.3.617 Steinberg, 1975, Role of suppressor T cells in autoimmunity in New Zealand mice, 174 Stobo, 1973, Functional heterogeneity of murine lymphoid cells. III. Differential responsiveness of T cells to phytohemagglutinin and concanavalin A as a probe for T cell subsets, J. Immunol., 110, 362, 10.4049/jimmunol.110.2.362 Stocker, 1976, Pathways to immunogical tolerance: An approach through the study of maturing B lymphocytes, Contemp. Top. Immunobiol., 5, 191 Strobël, 1972, The effect of thymectomy and thymocyte serum on the immunological competence of adult mice, Eur. J. Immunol., 2, 475, 10.1002/eji.1830020519 Stutman, 1974, Cell-mediated immunity and aging, 33, 2028 Tada, 1974, Selective roles of thymus-derived lymphocytes in the antibody response. I. Differential suppressive effect of carrier-primed T cells on hapten-specific IgM and IgG antibody responses, J. exp. Med., 140, 239, 10.1084/jem.140.1.239 Tada, 1976, Characterization of the antigen-specific suppressive T cell factor with special reference to the expression of I region genes, 513 Tada, 1976, Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response in the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex, J. exp. Med., 144, 713, 10.1084/jem.144.3.713 Tada, 1975, Properties of primed suppressor T cells and their products, Transplant Rev., 26, 106 Tadakuma, 1976, Biological expressions of lymphocyte activation. V. Characterization of a soluble immune response suppressor (SIRS) produced by concanavalin A-activated spleen cells, J. Immunol., 117, 323, 10.4049/jimmunol.117.1.323 Tadakuma, 1976, Site of action of a soluble immune response suppressor (SIRS) produced by concanavalin A-activated spleen cells, J. Immunol., 117, 967, 10.4049/jimmunol.117.3.967 Takemori, 1974, Selective role of thymus-derived lymphocytes in the antibody response. II. Preferential suppression of high-affinity antibody-forming cells by carrier-primed suppressor T cells, J. exp. Med., 140, 253, 10.1084/jem.140.1.253 Talal, 1976, Disordered immunologic regulation and autoimmunity, Transplant. Rev., 31, 240 Talal, 1974, The pathogenesis of autoimmunity in New Zealand black mice, Curr. Top. Microbiol. Immunol., 64, 79, 10.1007/978-3-642-65848-8_3 Taussig, 1973, Antigenic competition, Curr. Top. Microbiol. Immunol., 60, 125, 10.1007/978-3-642-65502-9_4 Taussig, 1973, Demonstration of suppressor T cells in a population of educated T cells, Nature, 248, 236, 10.1038/248236a0 Taussig, 1975, Antigen-specific T-cell factor in cell cooperation. Mapping within the I region of the H-2 complex and ability to cooperate across allogeneic barriers, J. exp. Med., 142, 694, 10.1084/jem.142.3.694 Theze, 1977, Immunosuppressive factor(s) extracted from lymphoid cells of nonresponder mice primed with L-glutamic acid60-L-alanine30-L-tyrosine10(GAT). III. Immunochemical properties of the GAT-specific suppressive factor, J. exp. Med., 10.1084/jem.145.4.839 Thomas, 1975, Regulation of the immune response: Production of soluble suppressor by immune spleen cells in vitro, J. Immunol., 114, 1616, 10.4049/jimmunol.114.5.1616 Thomas, 1976, Nature of the antigenic complex recognized by T lymphocytes. I. Analysis with an in vitro primary response to soluble protein antigens, J. exp. Med., 144, 1263, 10.1084/jem.144.5.1263 Tittor, 1974, Synergistic response between thymus and lymph node cells in the mixed lymphocyte culture, Nature, 247, 371, 10.1038/247371a0 Truitt, 1977, Suppression of cytotoxic lymphocyte generation in vitro by alloantigen-activated spleen cells, J. Immunol., 10.4049/jimmunol.119.1.31 Unanue, 1970, Thymus dependency of the immune response to hemocyanin: an evaluation of the role of macrophages in thymectomized mice, J. Immunol., 105, 1339, 10.4049/jimmunol.105.6.1339 Unanue, 1972, The regulatory role of macrophages in antigenic stimulation, Adv. Immunol., 15, 95, 10.1016/S0065-2776(08)60684-7 Unanue, 1976, Regulation of immunity and inflammation by mediators from macrophages, Am. J. Path., 85, 465 Vadas, 1976, Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression, J. exp. Med., 144, 10, 10.1084/jem.144.1.10 von Boehmer, 1975, Collaboration of histoincompatible T and B lymphocytes using cells from tetraparental bone marrow chimera, J. exp. Med., 142, 989, 10.1084/jem.142.4.989 Wagner, 1973, T-cell-mediated immune responses induced in vitro: A probe for allograft and tumor immunity, Transplant. Rev., 17, 3 Waksman, 1976, On soluble mediators of immunologic regulation, Cell. Immunol., 21, 161, 10.1016/0008-8749(76)90337-3 Waldmann, 1973, T cell dependent mediator in the immune response, Nature, Lond., 243, 356, 10.1038/243356a0 Waldmann, 1975, Cooperation across the allogeneic barrier, Nature, Lond., 258, 728, 10.1038/258728a0 Waldmann, 1974, Role of suppressor T cells in pathogenesis of common variable hypogammaglobulinemia, Lancet, ii, 609, 10.1016/S0140-6736(74)91940-0 Waldmann, 1977, Dysfunction of suppressor mechanisms associated with immunodeficiency and autoimmunity Waldmann, 1976, The role of suppressor cells in the pathogenesis of common variable hypogammaglobulinemia and the immunodeficiency associated with myeloma, 35, 2067 Warner, 1974, Membrane immunoglobulins and antigen receptors on B and T lymphocytes, Adv. Immunol., 19, 67, 10.1016/S0065-2776(08)60252-7 Wecker, 1974, A T cell produced mediator substance active in the humoral immune response, Ann. N. Y. Acad. Sci., 249, 258, 10.1111/j.1749-6632.1975.tb29073.x Weigle, 1973, Immunological unresponsiveness, Adv. Immunol., 16, 61, 10.1016/S0065-2776(08)60296-5 Whisler, 1976, Heterogeneity of murine regulatory T cells. I. Subpopulations of amplifier and suppressor T cells, J. exp. Med., 144, 398, 10.1084/jem.144.2.398 Zembala, 1973, Depression of the T cell phenomenon of contact sensitivity by T cells from unresponsive mice, Nature, 244, 227, 10.1038/244227a0 Zembala, 1974, T cell suppression of contact sensitivity in the mouse. II. The role of soluble suppressor factor and its interaction with macrophages, Eur. J. Immunol., 4, 799, 10.1002/eji.1830041206