Modification of C2 functional group on asiatic acid and the evaluation of hepatoprotective effects

Archives of Pharmacal Research - Tập 30 Số 3 - Trang 282-289 - 2007
Jeong, Byeong-Seon1, Lee, Mi Kyeong2, Kim, Young Choong2, Lee, Eung-Seok1
1College of Pharmacy, Yeungnam University, Kyongsan, Korea
2College of Pharmacy, Seoul National University, Seoul, Korea

Tóm tắt

For the development of novel hepatoprotective agents, C2 functional group on asiatic acid was modified, and evaluated for their hepatoprotective effects. Among prepared compounds, com-pounds10 and14 showed better hepatoprotective effects compared to Silymarin.

Tài liệu tham khảo

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