Modern extraction techniques and their impact on the pharmacological profile of Serenoa repens extracts for the treatment of lower urinary tract symptoms

Springer Science and Business Media LLC - Tập 14 - Trang 1-11 - 2014
Celeste De Monte1, Simone Carradori1, Arianna Granese1, Giovanni Battista Di Pierro2, Costantino Leonardo2, Cosimo De Nunzio3
1Department of Drug Chemistry and Technologies, “Sapienza” University of Rome, Rome, Italy
2Department of Obstetrics, Gynecology and Urology, Sapienza University of Rome, Rome, Italy
3Department of Urology, Ospedale Sant’Andrea, Sapienza University of Rome, Rome, Italy

Tóm tắt

Bioactive compounds from plants (i.e., Serenoa repens) are often used in medicine in the treatment of several pathologies, among which benign prostatic hyperplasia (BPH) associated to lower urinary tract symptoms (LUTS). There are different techniques of extraction, also used in combination, with the aim of enhancing the amount of the target molecules, gaining time and reducing waste of solvents. However, the qualitative and quantitative composition of the bioactives depends on the extractive process, and so the brands of the recovered products from the same plant are different in terms of clinical efficacy (no product interchangeability among different commercial brands). In this review, we report on several and recent extraction techniques and their impact on the composition/biological activity of S. repens-based available products.

Tài liệu tham khảo

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