Modeling gene–environment interactions in malignant melanoma

Trends in Molecular Medicine - Tập 9 - Trang 102-108 - 2003
Glenn Merlino1, Frances P. Noonan2
1Laboratory of Molecular Biology, National Cancer Institute, Building 37, Room 5002, Bethesda, MD 20892-4264, USA
2Dept of Environmental and Occupational Health, School of Public Health and Health Services, George Washington University Medical Center, Washington DC 20037, USA

Tài liệu tham khảo

Howe, 2001, Annual report to the nation on the status of cancer (1973 through 1998), featuring cancers with recent increasing trends, J. Natl. Cancer Inst., 93, 824, 10.1093/jnci/93.11.824 Jemal, 2001, Recent trends in cutaneous melanoma incidence among whites in the United States, J. Natl. Cancer Inst., 93, 678, 10.1093/jnci/93.9.678 Armstrong, 1997, Sun exposure and skin cancer, Australas. J. Dermatol., 38, S1, 10.1111/j.1440-0960.1997.tb01000.x Marks, 2000, Epidemiology of melanoma, Clin. Exp. Dermatol., 25, 459, 10.1046/j.1365-2230.2000.00693.x Kusewitt, 1996, Animal models of melanoma, Cancer Surv., 26, 35 Tietze, 2000, Murine models of malignant melanoma, Mol. Med. Today, 6, 408, 10.1016/S1357-4310(00)01781-0 Haluska, 1998, Molecular genetics of familial cutaneous melanoma, J. Clin. Oncol., 16, 670, 10.1200/JCO.1998.16.2.670 Goldstein, 2001, Genetic epidemiology of cutaneous melanoma: a global perspective, Arch. Dermatol., 137, 1493, 10.1001/archderm.137.11.1493 Chin, 1998, Malignant melanoma: modern black plague and genetic black box, Genes Dev., 12, 3467, 10.1101/gad.12.22.3467 Pollock, 2000, The genetics of cutaneous melanoma, Clin. Lab. Med., 20, 667 Chin, 1998, The INK4a/ARF tumor suppressor: one gene–two products–two pathways, Trends Biochem. Sci., 23, 291, 10.1016/S0968-0004(98)01236-5 Klein-Szanto, 1994, Ultraviolet radiation-induced malignant skin melanoma in melanoma-susceptible transgenic mice, Cancer Res., 54, 4569 Ali, 2001, Cellular transformation by SV40 large T antigen: interaction with host proteins, Semin. Cancer Biol., 11, 15, 10.1006/scbi.2000.0342 Chin, 1997, Cooperative effects of INK4a and ras in melanoma susceptibility in vivo, Genes Dev., 11, 2822, 10.1101/gad.11.21.2822 Bardeesy, 2001, Dual inactivation of RB and p53 pathways in RAS-induced melanomas, Mol. Cell. Biol., 21, 2144, 10.1128/MCB.21.6.2144-2153.2001 Krimpenfort, 2001, Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice, Nature, 413, 83, 10.1038/35092584 Sharpless, 2001, Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis, Nature, 413, 86, 10.1038/35092592 Sotillo, 2001, Invasive melanoma in Cdk4-targeted mice, Proc. Natl. Acad. Sci. U. S. A., 98, 13312, 10.1073/pnas.241338598 Rane, 2002, Germ line transmission of the Cdk4R24C mutation facilitates tumorigenesis and escape from cellular senescence, Mol. Cell. Biol., 22, 644, 10.1128/MCB.22.2.644-656.2002 Gilchrest, 1999, The pathogenesis of melanoma induced by ultraviolet radiation, N. Engl. J. Med., 340, 1341, 10.1056/NEJM199904293401707 Hersey, 2001, How melanoma cells evade trail-induced apoptosis, Nat. Rev. Cancer, 1, 142, 10.1038/35101078 Soengas, 2001, Inactivation of the apoptosis effector Apaf-1 in malignant melanoma, Nature, 409, 207, 10.1038/35051606 Griffith, 2000, Adenoviral-mediated transfer of the TNF-related apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosis, J. Immunol., 165, 2886, 10.4049/jimmunol.165.5.2886 Simpson, 2001, PTEN: life as a tumor suppressor, Exp. Cell Res., 264, 29, 10.1006/excr.2000.5130 You, 2002, Genetic analysis of Pten and Ink4a/Arf interactions in the suppression of tumorigenesis in mice, Proc. Natl. Acad. Sci. U. S. A., 99, 1455, 10.1073/pnas.022632099 Bennett, 1993, Genetics, development, and malignancy of melanocytes, Int. Rev. Cytol., 146, 191, 10.1016/S0074-7696(08)60383-6 Halaban, 1996, Growth factors and melanomas, Semin. Oncol., 23, 673 Shih, 1994, Autocrine and paracrine roles for growth factors in melanoma, In Vivo, 8, 113 Scott, 1991, Localization of basic fibroblast growth factor mRNA in melanocytic lesions by in situ hybridization, J. Invest. Dermatol., 96, 318, 10.1111/1523-1747.ep12465203 Wiltshire, 1995, Direct visualization of the clonal progression of primary cutaneous melanoma: application of tissue microdissection and comparative genomic hybridization, Cancer Res., 55, 3954 Bastian, 1998, Chromosomal gains and losses in primary cutaneous melanomas detected by comparative genomic hybridization, Cancer Res., 58, 2170 Kato, 1998, Transgenic mouse model for skin malignant melanoma, Oncogene, 17, 1885, 10.1038/sj.onc.1202077 Otsuka, 1998, c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype, Cancer Res., 58, 5157 Davies, 2002, Mutations of the BRAF gene in human cancer, Nature, 417, 949, 10.1038/nature00766 Pollock, 2003, High frequency of BRAF mutations in nevi, Nat. Genet., 33, 19, 10.1038/ng1054 Clark, 2000, Genomic analysis of metastasis reveals an essential role for RhoC, Nature, 406, 532, 10.1038/35020106 Cadet, 1997, Effects of UV and visible radiation on DNA-final base damage, Biol. Chem., 378, 1275 Hoeijmakers, 2001, Genome maintenance mechanisms for preventing cancer, Nature, 411, 366, 10.1038/35077232 Maestro, 1995, Sunlight and melanoma: an answer from MTS1 (p16), Science, 267, 15, 10.1126/science.7809600 Pollock, 1995, Evidence for UV induction of CDKN2 mutations in melanoma cell lines, Oncogene, 11, 663 Brash, 1991, A role for sunlight in skin cancer: UV-induced p53 mutations in squamous cell carcinoma, Proc. Natl. Acad. Sci. U. S. A., 88, 10124, 10.1073/pnas.88.22.10124 Tyrrell, 1996, Activation of mammalian gene expression by the UV component of sunlight – from models to reality, Bioessays, 18, 139, 10.1002/bies.950180210 Krutmann, 2000, Ultraviolet A radiation-induced biological effects in human skin: relevance for photoaging and photodermatosis, J. Dermatol. Sci., 23, S22, 10.1016/S0923-1811(99)00077-8 De Fabo, 1983, Mechanism of immune suppression by ultraviolet irradiation in vivo. Evidence for the existence of a unique photoreceptor in skin and its role in photoimmunology, J. Exp. Med., 158, 84, 10.1084/jem.158.1.84 Cleaver, 2000, Common pathways for ultraviolet skin carcinogenesis in the repair and replication defective groups of xeroderma pigmentosum, J. Dermatol. Sci., 23, 1, 10.1016/S0923-1811(99)00088-2 Kraemer, 1994, The role of sunlight and DNA repair in melanoma and nonmelanoma skin cancer. The xeroderma pigmentosum paradigm, Arch. Dermatol., 130, 1018, 10.1001/archderm.130.8.1018 Smith, 2002, p53 regulation of DNA excision repair pathways, Mutagenesis, 17, 149, 10.1093/mutage/17.2.149 Berg, 2000, Impact of global genome repair versus transcription-coupled repair on ultraviolet carcinogenesis in hairless mice, Cancer Res., 60, 2858 Meira, 2001, Cancer predisposition in mutant mice defective in multiple genetic pathways: uncovering important genetic interactions, Mutat. Res., 477, 51, 10.1016/S0027-5107(01)00097-5 van Steeg, 2001, DNA repair-deficient Xpa and Xpa/p53+/− knock-out mice: nature of the models, Toxicol. Pathol., 29, 109, 10.1080/019262301753178519 Matsumura, 2002, Molecular mechanisms of photocarcinogenesis, Front. Biosci., 7, D765, 10.2741/matsumur Herrlich, 1997, Nuclear and non-nuclear targets of genotoxic agents in the induction of gene expression. Shared principles in yeast, rodents, man and plants, Biol. Chem., 378, 1217 Shaulian, 2000, The mammalian UV response: c-Jun induction is required for exit from p53-imposed growth arrest, Cell, 103, 897, 10.1016/S0092-8674(00)00193-8 Herold, 2002, Negative regulation of the mammalian UV response by Myc through association with Miz-1, Mol. Cell, 10, 509, 10.1016/S1097-2765(02)00633-0 Teng, 2000, Protooncogenes as mediators of apoptosis, Int. Rev. Cytol., 197, 137, 10.1016/S0074-7696(00)97004-9 Shiloh, 2001, ATM and ATR: networking cellular responses to DNA damage, Curr. Opin. Genet. Dev., 11, 71, 10.1016/S0959-437X(00)00159-3 Zhang, 2002, Requirement of ATM in UVA-induced signaling and apoptosis, J. Biol. Chem., 277, 3124, 10.1074/jbc.M110245200 Unsal-Kacmaz, 2002, Preferential binding of ATR protein to UV-damaged DNA, Proc. Natl. Acad. Sci. U. S. A., 99, 6673, 10.1073/pnas.102167799 Rosette, 1996, Ultraviolet light and osmotic stress: Activation of the JNK cascade through multiple growth factor and cytokine receptors, Science, 274, 1194, 10.1126/science.274.5290.1194 Gross, 1999, Inactivation of protein-tyrosine phosphatases as mechanism of UV-induced signal transduction, J. Biol. Chem., 274, 26378, 10.1074/jbc.274.37.26378 Abdel-Malek, 1999, The melanocortin-1 receptor and human pigmentation, Ann. New York Acad. Sci., 885, 117, 10.1111/j.1749-6632.1999.tb08669.x Atillasoy, 1998, UVB induces atypical melanocytic lesions and melanoma in human skin, Am. J. Pathol., 152, 1179 Berking, 2001, Human skin reconstruct models: a new application for studies of melanocyte and melanoma biology, Histol. Histopathol., 16, 669 Kelsall, 1998, Metastatic cutaneous melanoma promoted by ultraviolet radiation in mice with transgene-initiated low melanoma susceptibility, Cancer Res., 58, 4061 Broome-Powell, 1999, Induction of melanoma in TPras transgenic mice, Carcinogenesis, 20, 1747, 10.1093/carcin/20.9.1747 Noonan, 2000, Accelerated ultraviolet radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice, Cancer Res., 60, 3738 Takayama, 1997, Diverse tumorigenesis associated with aberrant development in mice overexpressing hepatocyte growth factor/scatter factor, Proc. Natl. Acad. Sci. U. S. A., 94, 701, 10.1073/pnas.94.2.701 Noonan, 2001, Neonatal sunburn and melanoma in mice, Nature, 413, 271, 10.1038/35095108 Recio, 2002, Ink4a/Arf deficiency promotes ultraviolet radiation-induced melanomagenesis, Cancer Res., 62, 6724 Hirobe, 1984, Histochemical survey of the distribution of the epidermal melanoblasts and melanocytes in the mouse during fetal and postnatal periods, Anat. Rec., 208, 589, 10.1002/ar.1092080414 Holman, 1983, A theory of the etiology and pathogenesis of human cutaneous malignant melanoma, J. Natl. Cancer Inst., 71, 651 Whiteman, 2001, Childhood sun exposure as a risk factor for melanoma: a systematic review of epidemiologic studies, Cancer Causes Control, 12, 69, 10.1023/A:1008980919928 Berking, 2001, Basic fibroblast growth factor and ultraviolet B transform melanocytes in human skin, Am. J. Pathol., 158, 943, 10.1016/S0002-9440(10)64041-2 Berking, 2002, Photocarcinogenesis in human adult skin grafts, Carcinogenesis, 23, 181, 10.1093/carcin/23.1.181 Gabrielli, 1999, A cyclin D–Cdk4 activity required for G2 phase cell cycle progression is inhibited in ultraviolet radiation-induced G2 phase delay, J. Biol. Chem., 274, 13961, 10.1074/jbc.274.20.13961 Bishop, 2002, Geographical variation in the penetrance of CDKN2A mutations for melanoma, J. Natl. Cancer Inst., 94, 894, 10.1093/jnci/94.12.894 Kannan, K. et al. Components of the Rb pathway are critical targets of UV mutagenesis in melanoma. Proc. Natl. Acad. Sci. U. S. A. (in press). Serrano, 1996, Role of the INK4a locus in tumor suppression and cell mortality, Cell, 85, 27, 10.1016/S0092-8674(00)81079-X Chin, 1999, Essential role for oncogenic Ras in tumour maintenance, Nature, 400, 468, 10.1038/22788 Bradl, 1991, Malignant melanoma in transgenic mice, Proc. Natl. Acad. Sci. U. S. A., 88, 164, 10.1073/pnas.88.1.164 Kato, 2000, Ultraviolet radiation induces both full activation of ret kinase and malignant melanocytic tumor promotion in RFP-RET-transgenic mice, J. Invest. Dermatol., 115, 1157, 10.1046/j.1523-1747.2000.0202a-2.x Yang, 2001, Induction of melanoma in murine macrophage inflammatory protein 2 transgenic mice heterozygous for inhibitor of kinase/alternate reading frame, Cancer Res., 61, 8150 Zhu, 1998, Development of heritable melanoma in transgenic mice, J. Invest. Dermatol., 110, 247, 10.1046/j.1523-1747.1998.00133.x