Modeling colorectal tumorigenesis using the organoids derived from conditionally immortalized mouse intestinal crypt cells (ciMICs)

Genes and Diseases - Tập 8 - Trang 814-826 - 2021
Xiaoxing Wu1,2, Zhaoxia Li3, Hongyu Zhang1,2, Fang He1,2, Min Qiao1,2, Huaxiu Luo2,4, Jing Zhang1,2, Meng Zhang2,5, Yukun Mao2,6, William Wagstaff2, Yongtao Zhang2,7, Changchun Niu2,8, Xia Zhao2,7, Hao Wang2,9, Linjuan Huang1,2, Deyao Shi2,10, Qing Liu2,11, Na Ni2,9, Kai Fu2,6, Rex C. Haydon2
1Departments of Gastrointestinal Surgery, Medicine/Gastroenterology, and Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China
2Molecular Oncology Laboratory, Department of Orthopaedic Surgery and Rehabilitation Medicine, The University of Chicago Medical Center, Chicago, IL 606037, USA
3Department of Oncology, The PLA Rocket Force Characteristic Medical Center, Beijing, 100088, PR China
4Departments of Burn & Plastic Surgery, West China Hospital of Sichuan University, Chengdu, Sichuan Province, 610041, PR China
5Department of Orthopaedic Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, 510405, PR China
6Departments of Orthopaedic Surgery, The Affiliated Zhongnan Hospital of Wuhan University, Wuhan, Hubei Province, 430071, PR China
7Department of Orthopaedic Surgery, The Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, 266000, PR China
8Department of Clinical Laboratory Medicine, Chongqing General Hospital Affiliated with the University of Chinese Academy of Sciences, Chongqing, 400013, PR China
9Ministry of Education Key Laboratory of Diagnostic Medicine, and the School of Laboratory Diagnostic Medicine, Chongqing Medical University, Chongqing, 400016, PR China
10Department of Orthopaedics, Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, 430022, PR China
11Department of Spine Surgery, Second Xiangya Hospital, Central South University, Changsha, Hunan Province, 410008, PR China

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