Mitochondrial leader sequence-plasmid DNA conjugates delivered into mammalian cells by DQAsomes co-localize with mitochondria
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Chinnery, 1999, Peptide nucleic acid delivery to human mitochondria, Gene Ther., 6, 1919, 10.1038/sj.gt.3301061
D'Souza, 2004, Approaches to mitochondrial gene therapy, Curr. Gene Ther., 4, 317, 10.2174/1566523043346200
D'Souza, 2003, DQAsome-mediated delivery of plasmid DNA toward mitochondria in living cells, J. Control Release, 92, 189, 10.1016/S0168-3659(03)00297-9
Flierl, 2003, Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid, Mol. Ther., 7, 550, 10.1016/S1525-0016(03)00037-6
Geromel, 2001, Mitochondria transfection by oligonucleotides containing a signal peptide and vectorized by cationic liposomes, Antisense Nucleic Acid Drug Dev., 11, 175, 10.1089/108729001300338708
Larson, 1999, Revolution in mitochondrial medicine, FEBS Lett., 455, 199, 10.1016/S0014-5793(99)00854-6
Lasch, 1999, Dequalinium vesicles form stable complexes with plasmid DNA which are protected from DNase attack, Biol. Chem., 380, 647, 10.1515/BC.1999.080
Morin, 2001, Mitochondria as target for antiischemic drugs, Adv. Drug Deliv. Rev., 49, 151, 10.1016/S0169-409X(01)00132-6
Murphy, 2000, Drug delivery to mitochondria: the key to mitochondrial medicine, Adv. Drug Deliv. Rev., 41, 235, 10.1016/S0169-409X(99)00069-1
Schon, 2003, Medicinal and genetic approaches to the treatment of mitochondrial disease, Curr. Med. Chem., 10, 2523, 10.2174/0929867033456503
Singh, 2000, Mitochondrial me and the Mitochondrion journal, Mitochondrion, 1, 1, 10.1016/S1567-7249(00)00003-9
Weissig, 1998, DQAsomes: a novel potential drug and gene delivery system made from Dequalinium, Pharm. Res., 15, 334, 10.1023/A:1011991307631
Weissig, 2000, Selective DNA release from DQAsome/DNA complexes at mitochondria-like membranes, Drug Deliv., 7, 1, 10.1080/107175400266722
Weissig, 2001, DQAsome/DNA complexes release DNA upon contact with isolated mouse liver mitochondria, J. Control Release, 75, 401, 10.1016/S0168-3659(01)00392-3
Weissig, 2001, DNA binding cationic bolasomes with delocalized charge center. A structure-activity relationship study, S.T.P. Pharma. Sci., 11, 91
Zelphati, 1999, Gene chemistry: functionally and conformationally intact fluorescent plasmid DNA, Hum. Gene Ther., 10, 15, 10.1089/10430349950019156