Mitochondrial function in Parkinson’s disease cybrids containing an nt2 neuron-like nuclear background

Barroso, 1993, Respiratory chain enzyme activities in lymphocytes from untreated patients with Parkinson disease, Clin. Chem., 39, 667, 10.1093/clinchem/39.4.667 Beal, 2001, Experimental models of Parkinson’s disease, Nat. Rev. Neurosci., 2, 325, 10.1038/35072550 Benecke, 1993, Electron transfer complexes I and IV of platelets are abnormal in Parkinson’s disease but normal in Parkinson plus syndrome, Brain, 116, 1451, 10.1093/brain/116.6.1451 Bergmeyer, 1974, UV assay with pyruvate and NADH, 574 Binder, 2005, Molecular characterization of mtDNA depleted and replated NT2 cell lines, Mitochondrion, 5, 255, 10.1016/j.mito.2005.04.003 Blandini, 1998, Quantitative study of mitochondrial complex I in platelets of Parkinsonian patients, Movement Disord., 13, 11, 10.1002/mds.870130106 Bradford, 1976, A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein–dye binding, Anal. Biochem., 72, 248, 10.1016/0003-2697(76)90527-3 Cardoso, 2005, Neurodegenerative pathways in Parkinson’s disease: therapeutic strategies, Curr. Drug Targets CNS Neurol. Disord., 4, 405, 10.2174/1568007054546072 Cassarino, 1997, Elevated reactive oxygen species and antioxidant enzyme activities in animal and cellular models of Parkinson’s disease, Biochim. Biophys., 1362, 77, 10.1016/S0925-4439(97)00070-7 Coore, 1971, Regulation of adipose tissue pyruvate dehydrogenase by insulin and others hormones, Biochem. J., 125, 115, 10.1042/bj1250115 Cortopassi, 1995, Modelling the effects of age-related mtDNA mutation accumulation; Complex I deficiency; superoxide and cell death, Biochem. Biophys. Acta, 1271, 171 Cregan, 1999, Bax-dependent caspase-3 activation is a key determinant in p53-induced apoptosis in neurons, J. Neurosci., 19, 7860, 10.1523/JNEUROSCI.19-18-07860.1999 Gelb, 1999, Diagnostic criteria for Parkinson disease, Arch. Neurol., 56, 33, 10.1001/archneur.56.1.33 Ghosh, 1999, Use of cytoplasmatic hybrid cell lines for elucidating the role of mitochondrial dysfunction in Alzheimer’s disease and Parkinson’s disease, Ann. N. Y. Acad. Sci., 893, 176, 10.1111/j.1749-6632.1999.tb07825.x Gu, 1998, Mitochondrial DNA transmission of the mitochondrial defect in Parkinson’s disease, Ann. Neurol., 44, 177, 10.1002/ana.410440207 Haas, 1995, Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson’s disease, Ann. Neurol., 37, 714, 10.1002/ana.410370604 Ibeke, 1995, Point mutations of mitochondrial genome in Parkinson’s disease, Mol. Brain Res., 28, 281, 10.1016/0169-328X(94)00209-W Janetzky, 1994, Unaltered aconitase activity; but decreased complex I activity in substantia nigra pars compacta of patients with Parkinson’s disease, Neurosci. Lett., 169, 126, 10.1016/0304-3940(94)90372-7 Keeney, 2006, Parkinson’s disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled, J. Neurosci., 26, 5226, 10.1523/JNEUROSCI.0984-06.2006 King, 1967, Preparations of succinate-cytochrome c reductase and the cytochrome b–c1 particle and reconstitution of succinate-cytochrome c reductase, Methods Enzymol., 10, 216, 10.1016/0076-6879(67)10043-8 Kraytsberg, 2006, Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons, Nat. Genet., 38, 518, 10.1038/ng1778 Krige, 1992, Platelet mitochondrial function in Parkinson’s disease: the Royal Kings and Queens Parkinson Disease Research Group, Ann. Neurol., 32, 782, 10.1002/ana.410320612 Langston, 1983, Chronic Parkinsonism in humans due to a produce of meperidine-analog synthesis, Science, 219, 979, 10.1126/science.6823561 Manfredi, 2006, mtDNA clock runs out for dopaminergic neurons, Nat. Genet., 38, 507, 10.1038/ng0506-507 Miller, 1996, Creation and characterization of mitochondrial DNA-depleted cell lines with “neuronal-like” properties, J. Neurochem., 67, 1897, 10.1046/j.1471-4159.1996.67051897.x Mizuno, 1989, Deficiencies in complex I subunits of the respiratory chain in Parkinson’s disease, Biochem. Biophys. Res. Commun., 163, 1450, 10.1016/0006-291X(89)91141-8 Mochizuki, 1996, Histochemical detection of apoptosis in Parkinson’s disease, J. Neurol. Sci., 137, 120, 10.1016/0022-510X(95)00336-Z Mosmann, 1983, Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays, J. Immunol. Methods, 65, 55, 10.1016/0022-1759(83)90303-4 Parker, 1989, Electron transport chain abnormalities in idiopathic Parkinson’s disease, Ann. Neurol., 26, 719, 10.1002/ana.410260606 Parker, 2005, Mitochondrial ND5 mutations in idiopathic Parkinson’s disease, Biochem. Biophys. Res. Commun., 326, 667, 10.1016/j.bbrc.2004.11.093 Przedborski, 2004, MPTP as a mitochondrial neurotoxin model of Parkinson’s disease, J. Bioener. Biomembr., 36, 375, 10.1023/B:JOBB.0000041771.66775.d5 Ragan, 1987 Schapira, 1994, Platelet mitochondrial DNA in Parkinson’s disease, Movement Disord., 9, 119 Shapira, 1989, Mitochondrial complex I deficiency in Parkinson’s disease, Lancet, 1, 1289 Shapira, 1990, Mitochondrial complex I deficiency in Parkinson’s disease, J. Neurochem., 54, 823, 10.1111/j.1471-4159.1990.tb02325.x Shults, 2004, Mitochondrial dysfunction and possible treatments in Parkinson’s disease – a review, Mitochondrion, 4, 641, 10.1016/j.mito.2004.07.028 Shults, 1998, Reduced complex I activity in Parkinsonian cybrids, Movement Disord., 13, 217 Smigrodzki, 2004, High frequency of mitochondrial complex I mutations in Parkinson’s disease and aging, Neurobiol. Aging, 25, 1273, 10.1016/j.neurobiolaging.2004.02.020 Soong, 1992, Mosaicism for a specific somatic mitochondrial DNA mutation in adult human brain, Nat. Genet., 2, 318, 10.1038/ng1292-318 Stocchi, 1985, Simultaneous extraction and reverse-phase high-performance liquid chromatographic determination of adenine and pyridine nucleotides in human red blood cells, Anal. Biochem., 146, 118, 10.1016/0003-2697(85)90405-1 Swerdlow, 2004, A “mitochondrial cascade hypothesis” for sporadic Alzheimer’s disease, Med. Hypothesis, 63, 8, 10.1016/j.mehy.2003.12.045 Swerdlow, 1997, Cybrids in Alzheimer’s disease: a cellular model of the disease?, Neurology, 49, 918, 10.1212/WNL.49.4.918 Swerdlow, 1998, Matrilineal inheritance of complex I dysfunction in a multigenerational Parkinson’s disease family, Ann. Neurol., 44, 873, 10.1002/ana.410440605 Swerdlow, 1996, Origin and functional consequences of the complex I defect in Parkinson’s disease, Ann. Neurol., 40, 663, 10.1002/ana.410400417 Wharton, 1967, Cytochrome oxidase from beef heart mitochondria, Methods Enzymol., 10, 245, 10.1016/0076-6879(67)10048-7 Yoshino, 1992, Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson’s disease, J. Neural Transm. Park Dis. Dement. Sect., 4, 27, 10.1007/BF02257619