Mitochondrial and Nuclear Accumulation of the Transcription Factor ATFS-1 Promotes OXPHOS Recovery during the UPRmt

Bailey, 2009, MEME SUITE: tools for motif discovery and searching, Nucleic Acids Res., 37, W202, 10.1093/nar/gkp335 Baker, 2012, Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2, PLoS Genet., 8, e1002760, 10.1371/journal.pgen.1002760 Bestwick, 2013, Accessorizing the human mitochondrial transcription machinery, Trends Biochem. Sci., 38, 283, 10.1016/j.tibs.2013.03.006 Braeckman, 2002, Assessing metabolic activity in aging Caenorhabditis elegans: concepts and controversies, Aging Cell, 1, 82, 10.1046/j.1474-9728.2002.00021.x Bratic, 2009, Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development, Nucleic Acids Res., 37, 1817, 10.1093/nar/gkp018 Bratic, 2010, Caenorhabditis elegans as a model system for mtDNA replication defects, Methods, 51, 437, 10.1016/j.ymeth.2010.03.003 Buske, 2010, Assigning roles to DNA regulatory motifs using comparative genomics, Bioinformatics, 26, 860, 10.1093/bioinformatics/btq049 Chen, 2004, Binding of MCF-7 cell mitochondrial proteins and recombinant human estrogen receptors alpha and beta to human mitochondrial DNA estrogen response elements, J. Cell. Biochem., 93, 358, 10.1002/jcb.20178 Dennis, 2003, DAVID: Database for Annotation, Visualization, and Integrated Discovery, Genome Biol., 4, 3, 10.1186/gb-2003-4-5-p3 Falkenberg, 2007, DNA replication and transcription in mammalian mitochondria, Annu. Rev. Biochem., 76, 679, 10.1146/annurev.biochem.76.060305.152028 Ghezzi, 2012, Assembly factors of human mitochondrial respiratory chain complexes: physiology and pathophysiology, Adv. Exp. Med. Biol., 748, 65, 10.1007/978-1-4614-3573-0_4 Haynes, 2010, The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans, Mol. Cell, 37, 529, 10.1016/j.molcel.2010.01.015 Haynes, 2013, Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond, Trends Cell Biol., 23, 311, 10.1016/j.tcb.2013.02.002 Houtkooper, 2013, Mitonuclear protein imbalance as a conserved longevity mechanism, Nature, 497, 451, 10.1038/nature12188 Klinge, 2008, Estrogenic control of mitochondrial function and biogenesis, J. Cell. Biochem., 105, 1342, 10.1002/jcb.21936 Leonhard, 2000, Membrane protein degradation by AAA proteases in mitochondria: extraction of substrates from either membrane surface, Mol. Cell, 5, 629, 10.1016/S1097-2765(00)80242-7 Marinov, 2014, Evidence for site-specific occupancy of the mitochondrial genome by nuclear transcription factors, PloS One, 9, e84713, 10.1371/journal.pone.0084713 Mick, 2011, Inventory control: cytochrome c oxidase assembly regulates mitochondrial translation, Nat. Rev. Mol. Cell Biol., 12, 14, 10.1038/nrm3029 Mimaki, 2012, Understanding mitochondrial complex I assembly in health and disease, Biochim. Biophys. Acta, 1817, 851, 10.1016/j.bbabio.2011.08.010 Nargund, 2012, Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation, Science, 337, 587, 10.1126/science.1223560 Nolden, 2005, The m-AAA protease defective in hereditary spastic paraplegia controls ribosome assembly in mitochondria, Cell, 123, 277, 10.1016/j.cell.2005.08.003 Oliveira, 2009, Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf, Aging Cell, 8, 524, 10.1111/j.1474-9726.2009.00501.x Pagliarini, 2008, A mitochondrial protein compendium elucidates complex I disease biology, Cell, 134, 112, 10.1016/j.cell.2008.06.016 Park, 2011, Mitochondrial DNA mutations in disease and aging, J. Cell Biol., 193, 809, 10.1083/jcb.201010024 Pellegrino, 2014, Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection, Nature, 516, 414, 10.1038/nature13818 Pujol, 2013, Succinate dehydrogenase upregulation destabilize complex I and limits the lifespan of gas-1 mutant, PLoS ONE, 8, e59493, 10.1371/journal.pone.0059493 Rechtsteiner, 2010, The histone H3K36 methyltransferase MES-4 acts epigenetically to transmit the memory of germline gene expression to progeny, PLoS Genet., 6, e1001091, 10.1371/journal.pgen.1001091 Reinke, 2013, Networks of bZIP protein-protein interactions diversified over a billion years of evolution, Science, 340, 730, 10.1126/science.1233465 Rugarli, 2012, Mitochondrial quality control: a matter of life and death for neurons, EMBO J., 31, 1336, 10.1038/emboj.2012.38 Sano, 2001, Electrophoretic mobility shift scanning using an automated infrared DNA sequencer, Biotechniques, 31, 1056, 10.2144/01315st06 Scarpulla, 2012, Transcriptional integration of mitochondrial biogenesis, Trends Endocrinol. Metab., 23, 459, 10.1016/j.tem.2012.06.006 Schreiber, 2004, The estrogen-related receptor alpha (ERRalpha) functions in PPARgamma coactivator 1alpha (PGC-1alpha)-induced mitochondrial biogenesis, Proc. Natl. Acad. Sci. USA, 101, 6472, 10.1073/pnas.0308686101 Szczepanek, 2012, Multi-tasking: nuclear transcription factors with novel roles in the mitochondria, Trends Cell Biol., 22, 429, 10.1016/j.tcb.2012.05.001 Vafai, 2012, Mitochondrial disorders as windows into an ancient organelle, Nature, 491, 374, 10.1038/nature11707 van den Ecker, 2010, Blue native electrophoresis to study mitochondrial complex I in C. elegans, Anal. Biochem., 407, 287, 10.1016/j.ab.2010.08.009 Wu, 1999, Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1, Cell, 98, 115, 10.1016/S0092-8674(00)80611-X Yoneda, 2004, Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones, J. Cell Sci., 117, 4055, 10.1242/jcs.01275