Mismatch-CRISPRi Reveals the Co-varying Expression-Fitness Relationships of Essential Genes in Escherichia coli and Bacillus subtilis

Cell Systems - Tập 11 - Trang 523-535.e9 - 2020
John S. Hawkins1, Melanie R. Silvis1, Byoung-Mo Koo1, Jason M. Peters1, Hendrik Osadnik1, Marco Jost1,2,3,4, Cameron C. Hearne1, Jonathan S. Weissman2,3,4, Horia Todor1, Carol A. Gross1,5,6
1Department of Microbiology and Immunology, University of California, San Francisco, San Francisco, CA 94158, USA
2Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158, USA
3Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA
4California Institute for Quantitative Biosciences, University of California, San Francisco, San Francisco, CA 94158, USA
5Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94158, USA
6California Institute of Quantitative Biology, University of California, San Francisco, San Francisco, CA 94158, USA

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