Minimal residual disease based on patient specific Flt3-ITD and -ITT mutations in acute myeloid leukemia

Leukemia Research - Tập 29 - Trang 849-853 - 2005
Sebastian Scholl1, Ivan F. Loncarevic2, Claudia Krause1, Christa Kunert1, Joachim H. Clement1, Klaus Höffken1
1Department of Internal Medicine II (Oncology and Hematology), Friedrich Schiller University, Erlanger Allee 101, 07740 Jena, Germany
2Institute of Human Genetics, Friedrich Schiller University, Jena, Germany

Tài liệu tham khảo

Nakao, 1996, Internal tandem duplication of the flt3 gene found in acute myeloid leukemia, Leukemia, 10, 1911 Kiyoi, 1997, Internal tandem duplication of FLT3 associated with leucocytosis in acute promyelocytic leukemia, Leukemia, 11, 1447, 10.1038/sj.leu.2400756 Thiede, 2002, Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis, Blood, 99, 4326, 10.1182/blood.V99.12.4326 Kottaridis, 2001, Blood, 98, 1752, 10.1182/blood.V98.6.1752 Campana, 2003, Determination of minimal residual disease in leukaemia patients, Br J Haematol, 121, 823, 10.1046/j.1365-2141.2003.04393.x Stirewalt, 2001, Quantitative, real-time polymerase chain reactions for FLT3 internal tandem duplications are highly sensitive and specific, Leuk Res, 25, 1085, 10.1016/S0145-2126(01)00087-X Slavin, 1998, Nonmyeloablative stem cell transplantation and cell therapy as an alternative to conventional bone marrow transplantation with lethal cytoreduction for the treatment of malignant and nonmalignant hematologic diseases, Blood, 91, 756, 10.1182/blood.V91.3.756 Schnittger, 2004, Flt3 length mutations as marker for follow-up studies in acute myeloid leukaemia, Acta Haematol, 112, 68, 10.1159/000077561