Mild hyperhomocysteinemia, C677T polymorphism on methylenetetrahydrofolate reductase gene and the risk of macroangiopathy in type 2 diabetes: a prospective study

Giuseppina T. Russo1, A. Di Benedetto1, Domenico Magazzù2, Annalisa Giandalia1, Carlo Giorda3, Riccardo Ientile4, M. Previti1, E. Di Cesare1, Domenico Cucinotta1
1Department of Internal Medicine, Policlinico Universitario “G. Martino” Via C. Valeria, University of Messina, Messina, Italy
2Department of Health Sciences, Unit of Medical Statistics and Epidemiology, University of Pavia, Pavia, Italy
3Metabolism and Diabetes Unit, Chieri, Italy
4Department of Biochemical Sciences, University of Messina, Messina, Italy

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